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Merkel cell carcinoma

Merkel cell carcinoma: Critical review with guidelines for multidisciplinary management

Merkel cell carcinoma: Critical review with guidelines for multidisciplinary management

... The majority of patients with MCC (70%) pres- ent with stage I or II disease, 25% have palpable re- gional lymphadenopathy at presentation (stage III), and 5% present with distant metastases (stage IV). 3,4,54 The ...

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Merkel cell carcinoma occurring in a black woman: a case report

Merkel cell carcinoma occurring in a black woman: a case report

... Merkel cell carcinoma (MCC) is a rare and very aggres- sive neuroendocrine tumor of the skin ...cells—the Merkel cells—are located ...stem cell that acquires neuroendocrine features ...

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Case Report Primary merkel cell carcinoma of the oral mucosa: a case report with review of literature

Case Report Primary merkel cell carcinoma of the oral mucosa: a case report with review of literature

... Merkel cell carcinoma (MCC) is a rare cutane- ous neuroendocrine carcinoma that predomi- nantly occurs in the sun-exposed skin of the elderly ...

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Extensive central nervous system involvement in Merkel cell carcinoma: a case report and review of the literature

Extensive central nervous system involvement in Merkel cell carcinoma: a case report and review of the literature

... Case presentation: A 65-year-old Caucasian man presented with a sudden onset of severe headache and a three- month history of balance disturbance. Magnetic resonance imaging revealed a large meningeal metastasis. The ...

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Merkel cell carcinoma of the upper extremity: Case report and an update

Merkel cell carcinoma of the upper extremity: Case report and an update

... The overall 5-year survival rate for patients with Merkel cell carcinoma is 50% to 68% [38]. Considering the high incidence of local recurrence (27%–60%) regional node involvement (45%–91%) or ...

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Pancreatic metastasis of Merkel cell carcinoma and concomitant insulinoma: Case report and literature review

Pancreatic metastasis of Merkel cell carcinoma and concomitant insulinoma: Case report and literature review

... as Merkel cell ...primary Merkel carcinoma ...of Merkel cell carcinoma approximately two years after resection of a Merkel cell carcinoma resected ...

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Budget impact model of avelumab in patients with metastatic merkel cell carcinoma in the US

<p>Budget impact model of avelumab in patients with metastatic merkel cell carcinoma in the US</p>

... This study was sponsored by Merck Healthcare KGaA, Darmstadt, Germany, and is part of an alliance between Merck Healthcare KGaA, Darmstadt, Germany and P fi zer Inc., New York, NY, USA. We would like to acknowledge Olga ...

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Immunotherapy for Merkel cell carcinoma: a turning point in patient care

Immunotherapy for Merkel cell carcinoma: a turning point in patient care

... Merkel cell carcinoma (MCC) is a neuroendocrine-like tumor of the skin. First described in 1972, it is a rare diag- nosis, with an annual incidence of approximately 0.6 out of 100,000 persons in the ...

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Giant Merkel cell carcinoma of the eyelid: a case report and review of the literature

Giant Merkel cell carcinoma of the eyelid: a case report and review of the literature

... Merkel cell carcinoma (MCC) is a rare cutaneous tumor and cases located in the eyelid have been described, but still its rarity may lead to difficulty in diagnosis and delay in ...

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Merkel cell carcinoma: case report and literature review, from a remote region of France

Merkel cell carcinoma: case report and literature review, from a remote region of France

... After informed consent and local anaesthesia with Xylocaine TM 2%, an elliptical incision was made that included the lesion, and the specimen was immediately placed in formalin. The skin was closed with an interrupted ...

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Latest update on the clinical features and management of Merkel Cell Carcinoma

Latest update on the clinical features and management of Merkel Cell Carcinoma

... Neck Surgery, Georgetown University Hospital, Washington DC conducted a retrospective study and literature review in order to compare the clinical and histopathological criteria including tumour size and depth of ...

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Ileocaecal recurrence of Merkel cell carcinoma of the skin: a case report

Ileocaecal recurrence of Merkel cell carcinoma of the skin: a case report

... Merkel cell carcinoma (MCC) is an uncommon and highly aggressive skin ...from Merkel cells at the dermo-epidermal junction, which are of neu- roendocrine ...basal cell carcinoma ...

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Merkel Cell Carcinoma of the Axilla and Adrenal Gland: A Case Report with Imaging and Pathologic Findings

Merkel Cell Carcinoma of the Axilla and Adrenal Gland: A Case Report with Imaging and Pathologic Findings

... Copyright © 2015 Soo Heui Baek et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...

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Merkel Cell Carcinoma: A Rare Cause of Hypervascular Nasal Tumor

Merkel Cell Carcinoma: A Rare Cause of Hypervascular Nasal Tumor

... neuroendocrine carcinoma, first de- scribed in 1972, is an aggressive disease usually occurring in sun-exposed ...of Merkel cell carcinoma involving the sinonasal region, suggestive of a ...

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A case of long-term survival following hepatectomy for liver metastasis of Merkel cell carcinoma

A case of long-term survival following hepatectomy for liver metastasis of Merkel cell carcinoma

... Merkel cell carcinoma (MCC) is a relatively rare neuro- endocrine cancer in the skin with an age-adjusted inci- dence of less than 0.5 per 100,000 person-years [1]. Patients with MCC tend to have a ...

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Original Article Immunohistochemical expression of PAX5 and TdT by Merkel cell carcinoma and pulmonary small cell carcinoma: a potential diagnostic pitfall but useful discriminatory marker

Original Article Immunohistochemical expression of PAX5 and TdT by Merkel cell carcinoma and pulmonary small cell carcinoma: a potential diagnostic pitfall but useful discriminatory marker

... of Merkel cell carcinoma (n=20) from Emory University were stained using TdT (poly- clonal antibody, 1:40 dilution, DAKO, Carpinteria, CA) and PAX5 (clone 24, Cell Marque, Rocklin, CA, ...

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Recent updates in the management of Merkel Cell Carcinoma

Recent updates in the management of Merkel Cell Carcinoma

... Jr. Merkel cell carcinoma: 30-year experience from a single ...DG. Merkel cell carcinoma: prognosis and treatment of patients from a single inst it ...

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Merkel cell carcinoma of the head and neck: pathogenesis, current and emerging treatment options

Merkel cell carcinoma of the head and neck: pathogenesis, current and emerging treatment options

... Abstract: Merkel cell carcinoma (MCC) is a relatively uncommon, neuroendocrine, cutaneous malignancy that often exhibits clinically aggressive features and is associated with a poor pro­ ...of ...

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Case Report Metastatic merkel cell carcinoma in the bone marrow of a patient with plasma cell myeloma and therapy-related myelodysplastic syndrome

Case Report Metastatic merkel cell carcinoma in the bone marrow of a patient with plasma cell myeloma and therapy-related myelodysplastic syndrome

... Merkel cell carcinoma is known to be an aggres- sive tumor with a high rate of metastasis and ...plasma cell myeloma, previ- ously treated with thalidomide, melphalan, dexamethasone, and ...

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Involvement of Merkel Cell Polyomavirus in the Etiology and Pathogenesis of Merkel Cell Carcinoma: A Systematic Review

Involvement of Merkel Cell Polyomavirus in the Etiology and Pathogenesis of Merkel Cell Carcinoma: A Systematic Review

... Abstract: Merkel Cell Polyomavirus (MCV) is a virus belonging to the human Polyomavirus ...of Merkel Cell Carcinoma (MCC) tumors, it has been associated with this rare and aggressive ...

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