Mesenchymal stem/stromal cell
Mechanisms of mesenchymal stem/stromal cell function
... The role of MSCs in the protection of other damaged tissues has also been demonstrated. For example, intra- peritoneally and intravenously administered MSCs from murine bone marrow and adipose tissue had a protective ...
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Mesenchymal stem/stromal cell function in modulating cell death
... autophagy-related cell death in MSCs themselves and in the mouse neuron cell line Neuro2a in vitro when subjected to RCD cell sig- naling after deprivation of oxygen and glucose ...as cell ...
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The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open label pre test: post test study with blinded outcome assessments
... MSC: Mesenchymal Stem Cell / Multipotent mesenchymal stromal cell; MSCIMS: The mesenchymal stem cells in multiple sclerosis trial; MSFC: Multiple sclerosis ...
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Stem cells labeled with superparamagnetic iron oxide nanoparticles in a preclinical model of cerebral ischemia: a systematic review with meta-analysis
... embryonic stem cell; FFE, fast field echo; fMSC, fetal mesenchymal stem cell; FOV, field of vision; FSE, fast spin echo; GE, gradient echo ; GFAP, glial fibrillary acidic protein; GFP, ...
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Regenerative medicine in the treatment of idiopathic pulmonary fibrosis: current position
... of stem cell therapy, specifically mesenchymal stem cells (MSCs), a multipotent stromal cell population, which have demonstrated promising data in multiple animal models of ...
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Mesenchymal stromal cells in the development and therapy of bronchopulmonary dysplasia
... of stem/progenitor cell pop- ulations within the ...stalk mesenchymal cells into airway smooth muscle cells during epithelial budding and branching ...mature mesenchymal cells but also as ...
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Iberian pig mesenchymal stem/stromal cells from dermal skin, abdominal and subcutaneous adipose tissues, and peripheral blood: in vitro characterization and migratory properties in inflammation
... in cell therapy involves in vitro expansion to achieve a sufficient num- ber of cells, which implicitly carries the risk of propagat- ing cells with genetic abnormalities during cell ...for cell ...
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Chondrogenic induction of mesenchymal stromal/stem cells from Wharton’s jelly embedded in alginate hydrogel and without added growth factor: an alternative stem cell source for cartilage tissue engineering
... guide cell differenti- ation to chondrogenesis ...specific cell–material interactions play a role in this ...mediating cell–cell interactions during mes- enchymal condensation and ...
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Perinatal sources of mesenchymal stem cells: Wharton’s jelly, amnion and chorion
... of cell isolation from the stem cell niche reflect a great interest in the cells present in the amniotic ...as mesenchymal stem/stromal cells. Amniotic fluid mesenchymal ...
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Finding a new therapeutic approach for no option Parkinsonisms: mesenchymal stromal cells for progressive supranuclear palsy
... neural cell replacement is the ideal objective of any curative therapy for PSP, as in many other neu- rodegenerative disorders, up to now no approach can efficiently achieve this ...neural cell loss and ...
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Mesenchymal stem/stromal cells as a delivery platform in cell and gene therapies
... Failure of bone repair is often associated with a relevant morbidity. Therapies using recombinant BMP with or without biomaterials show promise of becoming a clinic- ally relevant procedure. However, the lack of optimal ...
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Mesenchymal stromal cells induce a permissive state in the bone marrow that enhances G-CSF-induced hematopoietic stem cell mobilization in mice
... determined and related to PBS controls (n = 4 6 per group). (C E) Relative RNA expression for (C) CXCL12, (D) VCAM, and (E) SCF was determined in bone-lining cells after MSC (M) or EV administration for 3 days to ...
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The clinical application of mesenchymal stromal cells in hematopoietic stem cell transplantation
... Mesenchymal stromal cells (MSCs), also called mesen- chymal stem cells, are multipotent progenitors which were first described by Caplan and colleagues in ...hematopoietic stem cell ...
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A magic kick for regeneration: role of mesenchymal stromal cell secretome in spermatogonial stem cell niche recovery
... Sertoli cell functions and contribute to the early stages of spermatogonial lineage expansions by supporting spermatogonia pools through secretions of GDNF, FGF2, and other paracrine factors that are im- portant ...
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Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol
... Several knowledge users of the results of this systematic review have been identified. These include the Canadian Perioperative Anesthesia Clinical Trials (PACT) Group, a network of academic perioperative medicine re- ...
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Are mesenchymal stromal cells immune cells?
... haematopoietic stem cell marker ...haematopoietic stem cells in mice led to the generation of GFP-positive micro- glial and perivascular cells [55], cells that are members of the MSC ...to ...
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Age, atherosclerosis and type 2 diabetes reduce human mesenchymal stromal cell-mediated T-cell suppression
... The overall efficacy of stem cell transplantation relies on the activity of donor cells and tissue environment. Our co-culture model is limited to MSCs and PBMCs and does not fully simulate all the ...
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Cellular therapy with human autologous adipose-derived adult cells of stromal vascular fraction for alopecia areata
... “stem cell” is given to a cell which has the ability to self-renew as well as to differentiate into defined cellular ...Multipotent stem cells are present in different adult tissues such as ...
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Umbilical cord as a long-term source of activatable mesenchymal stromal cells for immunomodulation
... for cell therapy, it is imperative to know whether early induced cultures are similar to those induced after prolonged culture ...higher stem cell potential (CD146+ cells) ...
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Human endometrial mesenchymal stem cells restore ovarian function through improving the renewal of germline stem cells in a mouse model of premature ovarian failure
... novel stem cell source has the superiority to conventional ...mal stem cells (EnSCs) with mesenchymal stem/stromal cells (MSCs) characteristics have been isolated from menstrual ...
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