mesenchymal stromal/stem cell
The clinical application of mesenchymal stromal cells in hematopoietic stem cell transplantation
... hematopoietic stem cells; HSCT: hematopoietic stem cell transplantation; ICAM: intercellular cell adhesion molecule; IDO: indoleamine 2,3-dioxygenase; Ig: immunoglobulin; IL: interleukin; ...
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Mesenchymal stromal cells induce a permissive state in the bone marrow that enhances G-CSF-induced hematopoietic stem cell mobilization in mice
... MSCs have been reported to secrete EVs [20]. To investigate whether EVs are the supernatant-derived factor that enhanced G-CSF-induced HSPC mobiliza- tion, EVs derived from 2 £ 10 6 to 0.2 £ 10 6 MSCs were administered ...
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Chondrogenic induction of mesenchymal stromal/stem cells from Wharton’s jelly embedded in alginate hydrogel and without added growth factor: an alternative stem cell source for cartilage tissue engineering
... guide cell differenti- ation to chondrogenesis ...specific cell–material interactions play a role in this ...mediating cell–cell interactions during mes- enchymal condensation and ...
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A magic kick for regeneration: role of mesenchymal stromal cell secretome in spermatogonial stem cell niche recovery
... Sertoli cell pools might be restored via mechanisms other than prolifera- tion ...Sertoli cell progenitors were previously localized in specific transi- ent zones in adult testis and were considered a ...
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Age, atherosclerosis and type 2 diabetes reduce human mesenchymal stromal cell-mediated T-cell suppression
... The overall efficacy of stem cell transplantation relies on the activity of donor cells and tissue environment. Our co-culture model is limited to MSCs and PBMCs and does not fully simulate all the ...
5
Mesenchymal stromal cells in the development and therapy of bronchopulmonary dysplasia
... to stem cell antigen-1 (Sca-1)-positive/CD90-negative lung (myo-)fibroblasts, Sca-1 ...epithelial cell triggers this reaction by secretion of prostaglandin E2 and parathyroid hormone-related protein ...
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Umbilical cord as a long-term source of activatable mesenchymal stromal cells for immunomodulation
... , transcriptome, clonal develop- ment, and the immune modulatory capacity of MSC-EM after different induction time points. First, we markedly im- proved the transduction of UCPs by targeting the proposed stem ...
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The mesenchymal stem cells in multiple sclerosis (MSCIMS) trial protocol and baseline cohort characteristics: an open label pre test: post test study with blinded outcome assessments
... MSC: Mesenchymal Stem Cell / Multipotent mesenchymal stromal cell; MSCIMS: The mesenchymal stem cells in multiple sclerosis trial; MSFC: Multiple sclerosis ...
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Are mesenchymal stromal cells immune cells?
... haematopoietic stem cell marker ...haematopoietic stem cells in mice led to the generation of GFP-positive micro- glial and perivascular cells [55], cells that are members of the MSC ...to ...
7
Perinatal sources of mesenchymal stem cells: Wharton’s jelly, amnion and chorion
... of cell isolation from the stem cell niche reflect a great interest in the cells present in the amniotic ...as mesenchymal stem/stromal cells. Amniotic fluid mesenchymal ...
22
Assessment of safety and efficacy of mesenchymal stromal cell therapy in preclinical models of acute myocardial infarction: a systematic review protocol
... Several knowledge users of the results of this systematic review have been identified. These include the Canadian Perioperative Anesthesia Clinical Trials (PACT) Group, a network of academic perioperative medicine re- ...
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Regenerative medicine in the treatment of idiopathic pulmonary fibrosis: current position
... of stem cell therapy, specifically mesenchymal stem cells (MSCs), a multipotent stromal cell population, which have demonstrated promising data in multiple animal models of ...
5
Mesenchymal stem/stromal cell function in modulating cell death
... lung injury in vivo in a mouse model [73]. Moreover, miRNA transfer via EVs produced by human MSCs alle- viated in vivo renal tubular epithelial RCD that can be apoptosis and/or necroptosis induced in vivo by glycerol or ...
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Mesenchymal stem/stromal cells as a delivery platform in cell and gene therapies
... This review highlights that injured organs may benefit from MSC as regenerative tools able to differentiate ac- cordingly, secrete useful factors, or both, with the final ef- fect of counteracting damages. The reported ...
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Iberian pig mesenchymal stem/stromal cells from dermal skin, abdominal and subcutaneous adipose tissues, and peripheral blood: in vitro characterization and migratory properties in inflammation
... in cell therapy involves in vitro expansion to achieve a sufficient num- ber of cells, which implicitly carries the risk of propagat- ing cells with genetic abnormalities during cell ...for cell ...
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Finding a new therapeutic approach for no option Parkinsonisms: mesenchymal stromal cells for progressive supranuclear palsy
... neural cell replacement is the ideal objective of any curative therapy for PSP, as in many other neu- rodegenerative disorders, up to now no approach can efficiently achieve this ...neural cell loss and ...
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Stem cells labeled with superparamagnetic iron oxide nanoparticles in a preclinical model of cerebral ischemia: a systematic review with meta-analysis
... embryonic stem cell; FFE, fast field echo; fMSC, fetal mesenchymal stem cell; FOV, field of vision; FSE, fast spin echo; GE, gradient echo ; GFAP, glial fibrillary acidic protein; GFP, ...
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Cellular therapy with human autologous adipose-derived adult cells of stromal vascular fraction for alopecia areata
... the mesenchymal stem cells markers, but also the panhematopoietic/monocyte/macrophage/endothelial/ pericyte markers and particularly high levels of ...1). Cell viability, as assessed by Trypan blue ...
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Mechanisms of mesenchymal stem/stromal cell function
... induce cell protrusions de novo, some of which formed TNTs with adjacent ...the cell membrane, LST1 was shown to interact with M-Sec, myosin, and myoferlin and also to recruit RalA, promoting its ...
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Human endometrial mesenchymal stem cells restore ovarian function through improving the renewal of germline stem cells in a mouse model of premature ovarian failure
... novel stem cell source has the superiority to conventional ...mal stem cells (EnSCs) with mesenchymal stem/stromal cells (MSCs) characteristics have been isolated from menstrual ...
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