mesial temporal lobe
Relationship between remnant hippocampus and amygdala and memory outcomes after stereotactic surgery for mesial temporal lobe epilepsy
... that mesial temporal structures and particularly the hippocampus play an important role in human ...is mesial temporal lobe epilepsy (MTLE), seizure activity is gener- ated from the ...
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Time Shift Homotopic Connectivity in Mesial Temporal Lobe Epilepsy
... MATERIALS AND METHODS: Resting-state functional MR imaging data were acquired from patients with unilateral mesial temporal lobe epilepsy (n ⫽ 62) (31 left- and 31 right-side) and healthy controls (n ...
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Influence of Resting State Network on Lateralization of Functional Connectivity in Mesial Temporal Lobe Epilepsy
... that mesial temporal lobe epilepsy may be a network-level disease; however, few investigations have examined resting-state functional connectivity of the entire brain, particularly in patients with ...
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Mesial temporal lobe epilepsy with psychiatric comorbidities: a place for differential neuroinflammatory interplay
... Mesial temporal lobe epilepsy (MTLE) is the most common cause of intractable epilepsy in adults and is characterized by hippocampal sclerosis, neuronal loss, gliosis, and mossy fiber sprouting ...
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Rare variants and de novo variants in mesial temporal lobe epilepsy with hippocampal sclerosis
... Mesial temporal lobe epilepsy related to hippocampal sclerosis (MTLE-HS) is among the most drug-resistant types of focal ...surrounding mesial temporal structures can be an effective ...
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In Vivo Mapping of Hippocampal Subfields in Mesial Temporal Lobe Epilepsy: Relation to Histopathology
... The human hippocampus is composed of a complex and heterogeneous structure. However, the hippocampus is usually modelled as a single structure in neuroimaging research; this is particularly due to the insufficient ...
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Detection of Mesial Temporal Lobe Hypoperfusion in Patients with Temporal Lobe Epilepsy by Use of Arterial Spin Labeled Perfusion MR Imaging
... left mesial temporal lobe (mTL) regions of inter- est (ROI) were manually drawn on the continuous ASL per- fusion images by one investigator ...around mesial temporal structures based ...
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Neurotrophin receptors expression in mesial temporal lobe epilepsy with and without psychiatric comorbidities and their relation with seizure type and surgical outcome
... Epilepsy and psychiatric comorbidities are frequently associated, but their common biological substrate is unknown. We have previously reported altered structural elements and neurotrophins (NTs) expression in ...
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Carbamazepine reduces memory induced activation of mesial temporal lobe structures: a pharmacological fMRI-study
... Carbamazepine (CBZ) is a widely used drug in neurology and psychiatry. CBZ was originally introduced as an an- ticonvulsant and nowadays is used as a first-line drug in patients with localization-related epilepsies [5]. ...
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Hippocampal Atrophy Is Associated with Altered Hippocampus–Posterior Cingulate Cortex Connectivity in Mesial Temporal Lobe Epilepsy with Hippocampal Sclerosis
... MATERIALS AND METHODS: Fifteen patients with left mesial temporal lobe epilepsy with hippocampal sclerosis and 15 healthy controls were included in the study. Multicontrast MR imaging, including ...
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Brain region and epilepsy-associated differences in inflammatory mediator levels in medically refractory mesial temporal lobe epilepsy
... AED: Antiepileptic drug; ANOVA: Analysis of variance; BBB: Blood-brain barrier; CHI: Moderate-to-severe closed head injury; CNS: Central nervous system; CRP: C- reactive protein; CSF: Cerebral spinal fluid; EDTA: ...
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Original Article Differential long non-coding RNA (lncRNA) profiles associated with hippocampal sclerosis in human mesial temporal lobe epilepsy
... Abstract: Objective: The aim of this study was to analyze the expression profiles of long non-coding RNA (lncRNAs) in human mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis (HS) and to ...
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Resting-state Functional Network Disruptions in a Rodent Model of Mesial Temporal Lobe Epilepsy (TLE)
... after the treatment. Villers, Godaux, and Ris (2012) established that long-lasting LTP can be induced either by single or repeated stimulations. A single IED originating in the hippocampus can propagate via monosynaptic ...
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Correlation of neuropsychological and metabolic changes after epilepsy surgery in patients with left mesial temporal lobe epilepsy with hippocampal sclerosis
... epileptogenic temporal lobe ...resected temporal lobe is associ- ated with significantly better postoperative seizure control ...poral lobe, likely representing areas of seizure ...
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3T MRI Quantification of Hippocampal Volume and Signal in Mesial Temporal Lobe Epilepsy Improves Detection of Hippocampal Sclerosis
... Although FreeSurfer software is not approved for clinical use by the US Food and Drug Administration, as far as we know, there is at least 1 software approved for automated volumetric an[r] ...
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Multisection Proton MR Spectroscopy for Mesial Temporal Lobe Epilepsy
... with no significant differences between epileptogenic and nonepileptogenic hemispheres, whereas hip- pocampal volumes were lateralizing (37). Glucose metabolism was found to be reduced over all supra- tentorial areas on ...
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Temporal Cortex Morphology in Mesial Temporal Lobe Epilepsy Patients and Their Asymptomatic Siblings
... These temporal re- gions are anatomically connected to the hippocampus, and often they display a similar atrophy pattern to that identified within the hippocampus (Moran et ...
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Clinical spectrum of STX1B-related epileptic disorders
... with mesial temporal lobe epilepsy and FS (for which common polymorphisms in SCN1A have been described Figure 2 Mutational density and paralog conservation scores of STX1B missense ...
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NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model
... Temporal lobe epilepsy patients and control group We collected the hippocampus samples of mTLE pa- ...ipsilateral mesial temporal lobe identified by 18F-FDG PET, without other patho- ...
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Practice parameter: Temporal lobe and localized neocortical resections for epilepsyReport of the Quality Standards Subcommittee of the American Academy of Neurology, in Association with the American Epilepsy Society and the American Association of Neurological Surgeons
... as mesial temporal lobe epilepsy, are needed to determine when in the course of the epi- leptic disorder this alternative therapy should be ...
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