Metabolic pathway
Metabolomics and metabolic pathway networks from human colorectal cancers, adjacent mucosa, and stool
... a pathway impact score of ...our pathway analysis revealed linkages to the glycolytic/gluconeogenic pathway and CRC tumorigenesis (pathway impact score of ...This metabolic ...
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Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer
... estrogen metabolic pathway has been a candidate pathway for the search of genetic var- iants related to mammographic ...estrogen metabolic pathway are generally investigated based on ...
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Utilising datasheets for the informed automated design and build of a synthetic metabolic pathway
... for metabolic genetic pathway de- sign, part information from a set of standard biological parts was uploaded to DoE software, ...the pathway design and analysis of a built heterologous ...
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Type IIs restriction based combinatory modulation technique for metabolic pathway optimization
... modulate gene expression one by one [5]. With this strat- egy, the possibility to achieve an optimized regulation pattern is very low. A better solution was to analyze all possible expression levels of pathway ...
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Linoleic acid metabolic pathway allows for an efficient increase of intramuscular fat content in pigs
... Over the last decades molecular markers have also raised interest as a tool to improve genetic analysis and selection. Several markers have been described to be as- sociated with IMF, BT and fatty acid composition, al- ...
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Amination, a Newly Discovered Metabolic Pathway of Myricetin and Baicalein
... There is a great diversity of the impact of our study. Amine is a reactive functional group, and the replacement of a hydroxyl group with an amino group may improve the bioactivities of dietary flavonoids. With this new ...
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Reconstruction of metabolic pathway for isobutanol production in Escherichia coli
... (EM) pathway as the central metabolism system to acquire energy from carbohydrates such as ...EM pathway, 1 mol of glucose is metabolized to 2 mol of pyruvate via 10-step ...alternative metabolic ...
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Metabolic distress in lipid & one carbon metabolic pathway through low vitamin B-12: a population based study from North India
... The present study does not support the complementing effect of “hcy-lipid”. Low vitamin B-12 was the main culprit, causing metabolic disturbance in both the metabolic pathways (lipid & one carbon ...
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Vitamin D and the promoter methylation of its metabolic pathway genes in association with the risk and prognosis of tuberculosis
... Methods: We performed a case-control study followed by a prospective cohort study. We recruited 122 patients with pulmonary tuberculosis and 118 healthy controls. The serum 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D ...
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Metabolic pathway analysis for in silico design of efficient autotrophic production of advanced biofuels
... by metabolic pathway analysis tools, specifically elementary mode analysis (EMA) and flux balance analysis ...cell’s metabolic flux profiles and its phenotypic spaces for the autotrophic production ...
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Metabolic pathway engineering for production of 1,2-propanediol and 1-propanol by Corynebacterium glutamicum
... Background: Production of the versatile bulk chemical 1,2-propanediol and the potential biofuel 1-propanol is still dependent on petroleum, but some approaches to establish bio-based production from renewable feed stocks ...
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The rabbit pulmonary cytochrome P450 arachidonic acid metabolic pathway: characterization and significance
... Microsomal fractions prepared from rabbit lung homogenates metabolized arachidonic acid through cytochrome P450 pathways, yielding cis-epoxyeicosatrienoic acids EETs and their hydration [r] ...
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Determination of key enzymes for threonine synthesis through in vitro metabolic pathway analysis
... Determination of the absolute enzyme concentrations The MS data were processed using Pioplite software with protein identification and quantification. APEX method was used to process the original label-free proteomics ...
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Metabolic pathway engineering of the toluene degradation pathway
... The program (or Virtual Instrument, in Lab View terminology) Carbon Fluxes uses lumped data (biomass, total carbon, CO 2) along with specific metabolite data (benzoate concentration) to [r] ...
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Metabolic Pathway Analysis for Nutrient Removal of the Consortium between C. vulgaris and P. aeruginosa
... genome-scale metabolic network for the consortium, the biochemical reactions were ordered in a matrix S with dimension m × n, whose rows (m) represent the mass balance for each metabolite (X), and n is the number ...
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Activation of the prostaglandin D2 metabolic pathway in Crohn’s disease: involvement of the enteric nervous system
... Results: In patients with active CD, inflamed colonic mucosa showed significantly higher COX2 and L-PGDS mRNA expression, and significantly higher PGD2 levels than healthy colonic mucosa[r] ...
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Synthetic metabolic pathway for the production of 1-alkenes from lignin-derived molecules
... Compared to the previous study [28], in which UndA was used for 1-undecene production, the titer obtained here was lower. This might be due to the difference of metabolism between E. coli and A. baylyi. In the afore- ...
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A novel approach for metabolic pathway optimization: Oligo-linker mediated assembly (OLMA) method
... Results: We reported a new DNA assembling method to vary all the above types of regulatory targets simultaneously, named oligo-linker mediated assembly (OLMA) method, which can incorporate up to 8 targets in a single ...
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Research and Application of Differential Equation System in Gene Regulation Network and Metabolic Pathway
... With the rapid increase in the number of organisms that complete sequencing and the wider understanding of gene functions, the study of biological networks has attracted more and more attention in bioinformatics. ...
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Synthetic metabolic engineering-a novel, simple technology for designing a chimeric metabolic pathway
... glycolytic pathway using individually purified yeast ...structed pathway is capable of converting 1 M (18% [w/v]) glucose to ethanol within 8 h with nearly 100% molar yield ...
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