Metabolism, Cellular
Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress
... Tumor metabolism is essential to meet the various meta- bolic demands associated with the proliferation and expan- sion of tumor ...tumor metabolism is the in- creased glucose utilization and excessive ...
19
Autophagy in cellular metabolism and cancer
... of cellular lipid and iron metabolism ...the cellular dysfunctions that lead to the development of degenerative conditions such as cardiovascular disease and various forms of ...
9
ABCC6- a new player in cellular cholesterol and lipoprotein metabolism?
... lipoprotein metabolism, regulatory properties in the extracellular matrix and intracellular calcium homeostasis were also described for APOE ...protective cellular response [67,68], a characteristic ...
17
Viral hijacking of cellular metabolism
... alter metabolism at both the cellular and whole organism ...and metabolism, and induction of oxi- dative stress through mitochondrial dysfunction ...lipid metabolism rewiring that occurs at an ...
15
The regulation of cellular metabolism by tumor suppressor p53
... of cellular en- ergy metabolism, p53 also plays a fundamental role in reducing the intracellular ROS levels mainly resulted from mitochondrial oxidative phosphorylation and maintaining the redox ...
10
Sestrins orchestrate cellular metabolism to attenuate aging
... Through regulation of the AMPK-mTORC1 signaling axis, the Sestrins promote metabolic adaptation of cells in response to diverse stress insults. Sesn1 and Sesn2, as p53-inducible genes, mediate DNA damage-induced ...
10
Ceramides as modulators of cellular and whole body metabolism
... Nearly all stress stimuli (e.g., inflammatory cytokines, glucocorticoids, chemotherapeutics, etc.) induce sphingolipid synthesis, leading to the accumulation of ceramides and ceramide metabolites. While the role of these ...
10
Aging: Past, Present and Future
... include cellular and molecular biology, cell metabolism, cellular senescence, autophagy, oncogenes and tumor sup- pressor genes, carcinogenesis, stem cells, pharmacology and anti-aging agents, animal ...
6
Series Introduction: The expanding network of redox signaling: new observations, complexities, and perspectives
... oxidative metabolism is central to the biology and health of all humans, how we respond to conditions of low and high oxygen stress has become a critical con- sideration in biology and ...of cellular NADPH ...
5
<p>Metabolic reprogramming results in abnormal glycolysis in gastric cancer: a review</p>
... the metabolism of pyruvate to lactic acid rather than oxidative phos- phorylation to generate energy under aerobic ...glucose metabolism, but they also affect mitochondrial functions, cellular ...
10
Schisandra fructus extract ameliorates doxorubicin-induce cytotoxicity in cardiomyocytes: altered gene expression for detoxification enzymes
... and cellular functions, and included genes involved in glutathione metabolism and detoxification (such as GST theta 1, mu 1, and alpha type 2, and heme oxygenase 1), lipid, carbohydrate and energy ...
9
ADAPTIVE REACTIONS INVESTIGATION UNDER EXPERIMENTAL HYPOXIA CONDITIONS WITH THE PRIOR TREATMENT OF THE 4 THIAZOLIDINONE DERIVATIVE
... of cellular oxidative metabolism (level of lipoperoxidation products, activity superoxide dismutase and catalase, levels and ratio of lactic and pyruvic acids in the blood and liver tissue) of the ...
7
Effect of Phyllanthus amarus extract on antioxidant and lipid metabolism gene expression in HepG2 cells
... percent cellular oxidative stress was calculated according to the following formula: % cellular oxidative stress = [(fluorescence of treated sample - blank) / (fluorescence of control sample - blank)] x ...
8
Among The Plant Seeds, Oil Producing Seeds Can Be A Promising Source Of Lead Compounds For The Palliative Treatment Of Non- Communicable Diseases: A Review
... As metabolism can be thought of changes in molecular level, inflammation and repair can be thought of changes in cellular to tissue levels: where replacement of faulty cells with healthy cells, or exclusion ...
5
Continuous multiparametric monitoring of cell metabolism in response to transient overexpression of the sirtuin deacetylase SIRT3
... cell metabolism over a defined period of time, in a closely monitored environment that mimics to the best a predetermined physiological ...of cellular oxygen consumption with modified clark-type sensors and ...
6
Metabolomics Analysis of Mesenchymal Stem Cells
... At first, human genome project has led to the advancement of genome sequencing and study on DNA by analysis of single nucleotide polymorphisms (SNPs), variation copies, and mutations (34-36). Nowadays, genomics as the ...
11
Age-related changes in the transcriptome of antibody-secreting cells
... in cellular metabolism of T cells and is expressed higher on aged B cells, we tested splenic ASCs for metabolic parameters and found that they carry higher levels of cellular reactive oxygen species ...
14
Arenavirus Infection Induces Discrete Cytosolic Structures for RNA Replication
... into cellular processes to orchestrate productive viral replication, we have identified and characterized novel cytosolic structures involved in arenavirus replication and ...with cellular membranes and ...
11
Mitochondria in lung disease
... changing cellular location via cytoskeletal motors and altering size and shape in response to the metabolic needs of the ...or cellular stress ...OXPHOS metabolism, such as type II AECs, have more ...
13
Intrinsic Factor mediated Absorption of Cobalamin by Guinea Pig Ileal Cells
... block cellular metabolism, virtually all cellular radioactivity could be removed by washing the cell surface with EDTA or ...residual cellular radioactivity was extracted and analyzed by gel ...
10