Metallo Beta Lactamase
“Potential Threat of New Delhi Metallo-Beta-Lactamase-1 Enzyme, Multi Drug Resistant and Extensive Drug Resistant (XDR) to Achieve the Millennium Development Goals (MGD’S) in South East Asian Countries” by Taha Nazir, Saeed Ur Rashid Nazir, Azharul Islam, Misbah Sultana, Humayun Riaz, Nida Taha, Canada.
... Delhi Metallo-beta- lactamase-1 (NDM-1) enzyme resistant, Multi Drug Resistant (MDR) and Extensive Drug Resistant (XDR), Methicillin Resistant Staphylococcus Aureus (MRSA), Carbapenem-Resistant ...
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INSILICO MODELING AND DOCKING STUDIES OF NEW DELHI METALLO BETA LACTAMASE-1 (SUPER BUG)
... Delhi Metallo Beta Lactamase-1 (NDM-1) is a novel beta -lactamase enzyme that is ubiquitously found in Escherichia ...of Metallo Beta Lactamases and is known to induce ...
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A hospital based surveillance of metallo beta lactamase producing gram negative bacteria in Nepal by imipenem EDTA disk method
... The findings of our study demonstrated a higher preva- lence of MDR and MBL positive P. aeruginosa and Aci- netobacter spp., which have been globally incriminated with adverse clinical outcome including a higher mor- ...
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The prevalence of Metallo-beta-lactamase (MBL) in gram negative bacilli and their antimicrobial susceptibility pattern at tertiary care hospital, Surendranagar
... BACKGROUND AND OBJECTIVE: Antimicrobial resistance remains the major threat due to broad spectrum usage of antimicrobials in community practice. The present study is aimed to determine the prevalence of ...
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Detection of Metallo-Beta-lactamase Production in Rare Carbapenem-Resistant Non-fermentative Gram-Negative Bacilli Isolated in a Tertiary Care Hospital, Visakhapatnam, India
... Introduction: Non-fermentative Gram-negative bacilli (NFGNB) are occasionally involved in infectious diseases pathology, but have shown resistance to multiple antibiotics and the capability to gain new resistance factors ...
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Detection and Characterisation of Metallo Beta Lactamase Production in Pseudomonas Aeruginosa by Phenotypic and Molecular Methods from Clinical Isolates in a Tertiary Care Hospital
... the metallo beta lactamase producing ...the metallo beta lactamase using PCR is available only in the reference center is the limitation regarding the gene ...
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A Study on Detection and Characterisation of Metallo Beta Lactamase Producing Pseudomonas Aeruginosa.
... Pseudomonas aeruginosa is one of the leading causes of nosocomial infections giving rise to a wide range of life threatening conditions. The intrinsic resistance exhibited by Pseudomonas to a wide range of antibiotics ...
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Impact of the New Delhi metallo-beta-lactamase on beta-lactam antibiotics
... Delhi metallo-beta-lactamase (NDM) report in 2009, NDM has spread globally causing various types of ...and beta-lactamase inhibitor combinations, may retain utility against infections ...
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Arbekacin treatment of a patient infected with a Pseudomonas putida producing a metallo-beta-lactamase
... Treatment of infections caused by multidrug-resistant Pseudomonas species is difficult because few antibiotics active against such organisms are available. Arbekacin, a relatively new aminoglycoside, is effective against ...
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Extended spectrum beta-lactamase and metallo beta-lactamase production among Escherichia coli and Klebsiella pneumoniae isolated from different clinical samples in a tertiary care hospital in Kathmandu, Nepal
... spectrum beta-lactamase (ESBL) and metallo beta-lactamase (MBL) production in Klebsiella pneumoniae and Escherichia coli are the commonest modes of drug resistance among these commonly ...
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Extended spectrum and metallo-beta-lactamase Pseudomonas species from poultry and piggery waste
... ABSTRACT: Beta-lactamase producing bacteria have become a public health burden due to antibiotics usage in livestock ...spectrum beta-lactamase (ESBL) and ...
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Study on klebsiella pneumoniae carbapenemase and metallo beta lactamase enzymes in clinical isolates of gram negative bacilli
... various body fluids, CSF, endo-tracheal tube, vaginal swabs, conjunctival swab, ear discharge etc. Out of the 250 samples, majority of the isolates were from pus 86 (34.4%), followed by urine 72 (26.8%), sputum 40 (16%), ...
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Paramagnetism & structural biology : biochemical & biophysical analysis of imp-1 metallo-beta-lactamase
... Figure 2-1 The chemical structures of clinical β-lactam drugs. A) The penams consist of the β-lactam ring fused with a 5-membered thiazolidine ring. The ring further destabilises the strained C-N amide bond of the ...
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PCR detection of metallo beta lactamase gene (blaIMP) in gram negative rods resistant to broad spectrum beta lactams
... new metallo- b -lactamase, IMP-1, which efficiently hydrolyzes carbapenems as well as broad-spectrum b -lactams (3, 12, 15, ...the metallo- b -lactamase gene (bla IMP ) cassette of Serratia ...
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Burn Patients Infected With Metallo-Beta-Lactamase-Producing Pseudomonas aeruginosa: Multidrug-Resistant Strains
... embedded in the API-20E biochemical kit system (Bio-Mer- ieux, France) and manual biochemical tests were used in accordance with the manufacturer’s instructions. Strains were preserved at -20℃ on tryptic soy broth (TSB; ...
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Study of metallo beta lactamase production and biofilm formation of pseudomonas aeruginosa in clinical isolates
... Acquired metallo-β lactamases (MBL) have recently emerged as one of the most troublesome resistance mechanisms owing to their capacity to hydrolyze all β-lactams including carbapenems and also because their genes ...
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INCIDENCE AND DETECTION OF METALLO BETA LACTAMASE PRODUCING P MIRABILIS IN A TERTIARY CARE HOSPITAL AT CENTRAL INDIA
... other beta lactam group and to other classes of antibiotics was distributed as follows: TET (75%;R), SXT (77%;R), AMP(90%;R), AMC (87%;R), SAM (81;R), CRO (82%;R), ATM(81%;R), CTX(81%;R), CZ(82%;R), CPZ (80%;R), ...
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Sensitive and Rapid Detection of the New Delhi Metallo Beta Lactamase Gene by Loop Mediated Isothermal Amplification
... Delhi metallo-  -lactamase 1 (NDM-1) in Chennai, India; 26 in Haryana, India; 37 in the United Kingdom; and 73 in other sites in India and Pakistan ...
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Detection of P aeruginosa harboring bla CTX M 2, bla GES 1 and bla GES 5,bla IMP 1 and bla SPM 1causing infections in Brazilian tertiary care hospital
... to beta-lactam drugs are one of the most challenging targets for antimicrobial therapy, leading to substantial increase in mortality rates in hospitals ...of metallo-beta-lactamase (MBLs) and ...
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Physical Inactivity: A Social Burden
... A combined disc test was performed using two imipenem (10 µg) discs, one containing 10 μl of 0.1 M (292 μg) anhydrous EDTA (Sigma Chemicals, St. Louis, MO). Discs were placed 25 mm apart (centre to centre) on ...
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