Metallothionein Gene
Metallothionein Gene Duplications and Metal Tolerance in Natural Populations of Drosophila melanogaster
... Metallothionein Gene Duplications and Metal Tolerance in Natural Populations of Drosophila melanogasterG. Otto.[r] ...
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Seasonal assessment of some heavy metal pollution and Metallothionein gene expression in cultured Oreochromis niloticus
... Metallothionein gene, as a biomarker for water pollution with heavy metals, and beta actin (β-Actin), as internal control, were used in the present study; primers were ob- tained from Macrogen (Grand ...
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MOLECULAR AND CYTOGENETIC CHARACTERIZATION OF A METALLOTHIONEIN GENE OF DROSOPHILA
... A chromosomal DNA segment containing the metallothionein gene was iso- lated from a genomic library of Drosophila melanogaster using a previously char- acterized cDNA [r] ...
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Accumulation of Cadmium by Transgenic Tobacco Plants (Nicotiana tabacum L.) Carrying Yeast Metallothionein Gene Revealed by Electrochemistry
... The growing knowledge of the factors important for the phytoremediation can provide a basis for targeted genetic modifications of plants for improving of phytoremediation potential [80]. The use of genetically engineered ...
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Bioinformatics analysis of metallothionein gene from Agaricus bisporus, Ganoderma lucidum, Taiwanofungus camphorates and Paxillus involutus
... Structures and properties of nucleotide and corre- sponding amino acid sequences of MT genes from A. bisporus, G. lucidum, T. camphoratus and P. involutus were obtained by ProtParam tool (Table 1). GlMT, TcMT and PiMT ...
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Molecular evolution of the metallothionein gene Mtn in the melanogaster species group: results from Drosophila ananassae.
... melunogasterand the other species revealed that 36 of the 45 introns available belonged either to the small size class (<90 bp) or to the large one in both species. In the remaini[r] ...
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Cadmium accumulation and metallothionein gene expression in the liver of swamp eel (Monopterus albus) collected from the Mae Sot District, Tak Province, Thailand.
... MT gene expression biomarker was probably more sensitive and suitable for acute (short- term) exposure but not for chronic (long-term) exposure to heavy metals (Quirós et ...
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Identification of metallothionein gene structure in sterlet (Acipenser ruthenus)
... The phylogenetic tree was done and the relationship of S-MT to MTs from other species of fishes, mammals, amphibians, and birds was shown. Alignments of the sequences for this gene region were analyzed in a ...
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Metallothionein messenger RNA regulation in the mottled mouse and Menkes kinky hair syndrome
... in metallothionein gene regulation. We show that metallothionein-I messenger RNA (mRNA) (mouse) and metallothionein-II mRNA (human) are elevated in mutant ...mouse metallothionein-I ...
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The evaluation of cadmium, zinc and nickel accumulation ability of transgenic tobacco bearing different transgenes
... yeast metallothionein gene alone did not significantly increase the accumulation compare to the average of the controlled ...lothionein gene may be useful in improving metal tolerance of ...of ...
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Metallothioneins of the South American opossum, Monodelphis domestica
... vertebrate metallothionein gene family indicates that the amplification of ancestral genes into multiple isoforms occurred independently in both mammalian lineages.. It can be inferred t[r] ...
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Effect of ZnO nanoparticle on cell viability, zinc uptake efficiency, and zinc transporters gene expression: a comparison with ZnO and ZnSO4
... include metallothionein (MT), divalent metal transporter (DMT-1), and transmembrane zinc transporters ...addition, metallothionein (MT) is a kind of low-molecular- weight proteins, which can maintain ...
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Metallothionein III (MT3) is a putative tumor suppressor gene that is frequently inactivated in pediatric acute myeloid leukemia by promoter hypermethylation
... Consistent with the cell line results, we found that the MT3 promoter was methylated in samples obtained from patients with pediatric AML. Aberrant methylation of MT3 was observed 39.0% (16/41) of pediatric AML sam- ples ...
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Towards an Understanding of Specific Response of Metallothionein (Sub)Isoforms to Exposure to Platinum-Based Anticancer Drugs
... that MT 1, 2 and 3 expression manifested the highest qPCR activity after CisPt treatment (both healthy and cancer cells). We can also conclude that in principle, the platinum drug-induced overexpression of all ...
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Reactions between Zinc Metallothionein and Carbonic Anhydrase
... The recombinant human MT1A genes were engineered in the laboratory of Dr. Peter Kille at Cardiff University, Wales. The MT genes were inserted into pET-29a plasmids that contain a kanamycin resistance marker, a ...
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Non-Traditional Metallation of Metallothioneins with Xenobiotic Therapeutic Metals
... on metallothionein and other low molecular weight metal-binding proteins, Vallee, one of the original discoverers of equine MT, describes metallothionein as a “sphinx’s ...
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Isolation and partial characterisation of a calcium dependent lectin like protein from the flat oyster, Ostrea chilensis : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Pathology at Massey University, Palmerston North, New Zealand
... by gene rearrangements, however, all animals have evolved some kind of response to recognise and eliminate non-self without destroying self Many studies have been undertaken to see if invertebrates are capable of ...
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Structural Motifs of Novel Metallothionein Proteins
... Metallothionein (MT) was first isolated from horse kidney cortex in 1957. This first isolation of MT relied upon retaining the cadmium content present in kidney homogenate following a series of purifications. In ...
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Genome-wide DNA methylation analysis reveals estrogen-mediated epigenetic repression of metallothionein-1 gene cluster in breast cancer
... hypermethylated gene clusters. Interestingly, we found five gene clusters, ZNF, PCDH, MT1, HOXD, and HOXA, which showed re- duced expression in cancer patients compared to normal ...other gene ...
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Zinc and low-dose of cadmium protect sertoli cells against toxic-dose of cadmium: The role of metallothionein
... Quantitative real-time RT PCR analysis Real-time RT PCR was carried out with Quantifast SYBR Green Kit (Roche Applied Science, UK) using 1 μl of cDNA (equivalent to 100 ng cDNA) in a 20 μl final volume and 0.4 μM of each ...
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