Metastatic process
CXCR6 expression in non-small cell lung carcinoma supports metastatic process via modulating metalloproteinases
... and metastatic disease ...this process will be essential for reducing LuCa related mortality ...the metastatic process in many cancers [6–20], including LuCa [8, 21, ...
14
Dysregulation of macrophage polarization is associated with the metastatic process in osteosarcoma
... The pathogenesis of OS is closely related to the microenvironment in which the tumor grows. Even if the etiology of OS has not been clearly established, its development has the special feature of being strongly ...
12
Dysregulation of macrophage polarization is associated with the metastatic process in osteosarcoma
... The pathogenesis of OS is closely related to the microenvironment in which the tumor grows. Even if the etiology of OS has not been clearly established, its development has the special feature of being strongly ...
12
Effects of radiation on the metastatic process
... As for irradiation of putative sites of metastasis, contradictory results have been noted. On the one hand, Travis et al. observed that irradiation of the whole lung (14,5 or 20 Gy) after the subcutaneous growth of sar- ...
20
Interleukin-34 promotes tumor progression and metastatic process in osteosarcoma through induction of angiogenesis and macrophage recruitment
... Angiogenesis and vasculogenesis are central events during embryogenesis and growth [1, 2]. They are also strongly implicated in the pathogenesis of inflammation, by promoting immune cell extravasation, and of cancer, by ...
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Molecular profiling of circulating tumor cells links plasticity to the metastatic process in endometrial cancer
... the process of metastasis and a challenge in ...of metastatic tumor cells at a cellular level in lymph nodes, peripheral blood or bone marrow, prior to the manifestation of ...
10
Similarity between Some Biological Systems, Organotropism and Metastatic Process: Active Role Played By Secondary Organ?
... human metastatic tumors also contain neoplastic cells with macrophage ...consider metastatic cells themselves as derived from macrophages or other similar cells of myeloid ...
33
Micro-RNA in pancreatic adenocarcinoma: predictive/prognostic biomarkers or therapeutic targets?
... and its downregulation is associated with worse survival in PDAC patients. The role of miRNA-124 as a tumor suppressor has been recently investigated by Wang et al who identified Rac1, a putative tumor promoter in PDAC, ...
19
The Role of Ultrasonography and Fine Needle Aspiration Cytology in the Diagnosis of Neck Swellings - Our Experience
... inflammatory process or infiltration by metastatic malignant cells), thyroid gland (goitre, thyroiditis, benign and malignant tumours), salivary glands (sialadinitis, cysts, benign and malignant tumours) ...
5
Visualization of Tumor-Immune Interaction - Target-Specific Imaging of S100A8/A9 Reveals Pre-Metastatic Niche Establishment
... This study provides the first evidence that S100A8/A9 can be used as a non-invasive imaging marker, for the establishment of a tumor-permissive, immunosuppressive environment in target organs of metastasis. S100A8/A9 ...
10
Small RNAs in metastatic and non-metastatic oral squamous cell carcinoma
... between metastatic and non-metastatic ...the metastatic process, were over-expressed in non-metastatic samples and the expression of miR-130b was confirmed in plasma of patients showing ...
15
C-met inhibition blocks bone metastasis development induced by renal cancer stem cells
... microenvironment [27], we propose it as a suitable candidate to disrupt bone metastatic process. TK and more specific MET inhibitors have been tested and clinical trials are ongoing for the treatment of RCC ...
13
MDA-9/Syntenin (SDCBP) modulates small GTPases RhoA and Cdc42 via transforming growth factor β1 to enhance epithelial- mesenchymal transition in breast cancer
... and metastatic lesions was probed for MDA-9 expression by ...and metastatic lesions showed an increased expression of MDA-9 as compared to normal breast tissue (Figure ...and metastatic breast cancer ...
15
Bioprinting in Vascularization Strategies
... simultaneously. First, they optimized the composition of a biological bioink composed of gelatin methacryloyl (Gel-MA) and alginate. Subsequently, they developed a microfluidic printhead for bioprinting this ...
12
Profiling and targeting HER2-positive breast cancer using trastuzumab emtansine
... or Metastatic Breast Cancer; TH3RESA, A Study of Trastuzumab Emtansine in Comparison With Treatment of Physician’s Choice in Patients With HER2-positive Breast Cancer Who Have Received at Least Two Prior Regimens ...
10
Brain metastases in newly diagnosed colorectal cancer: a population-based study
... Table 4 displays the median survival by subtype as stratified by the extent of systemic disease in the cohort of extracranial systemic disease only and the cohort of extra- cranial systemic disease and BM. In addition, ...
10
Risk factors for the development of brain metastases in patients with HER2-positive breast cancer
... Out of 483 eligible patients identified using the hospital cancer registry, 108 patients (22.4%) were diagnosed with MBC (including BM) and 52 (10.8%) developed BM. Among the 52 BM, 7 patients (13.5%) had BM as first ...
9
18F-FDG PET/CT Optimizes Treatment in Staphylococcus Aureus Bacteremia and Is Associated with Reduced Mortality.
... for metastatic infection, a risk score previously described by Fowler et al (3) was used; community‐ acquisition, persistent fever >72 hours, and skin findings suggesting the presence of metastatic ...
24
Role of trastuzumab in the management of HER2-positive metastatic breast cancer
... for metastatic disease and evaluated genotypes for the Fc γ RIIIa-158 valine(V)/phenylalanine(F), Fc γ RIIa-131 histidine(H)/arginine(R), and Fc γ RIIb-232 isoleucine(I)/threonine(T) ...
17
The Role Of Calcineurin/nfat Signaling In Fibroblast Homeostasis And Activation
... The in vivo data presented in Chapter 2 suggest that the phenotypic changes observed in lung fibroblasts in vitro are relevant to in vivo models of metastasis, as the pro- tumorigenic changes observed in functional ...
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