microdialysis probe
Plasma binding and transport of diazepam across the blood brain barrier No evidence for in vivo enhanced dissociation
... barrier. Microdialysis probes placed within the vena cava and brain cortex were used to directly compare steady-state, interstitial unbound diazepam levels in both Wistar and genetically analbuminemic ...
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Regional differences in the mechanisms underlying the modulation of noradrenaline efflux in the brain by the CNS stimulant, d-amphetamine: A dual-probe microdialysis study in the rat
... In 1966, Bito et a l published the first results obtained with a new method that would later become in vivo microdialysis. By placing a permeable sack, containing 6% dextran in saline, into the brain of dogs, they ...
242
Muscarinic and GABA A receptors modulate acetylcholine release in feline basal forebrain
... inferences about the subtype which functions as an autoreceptor in F IG . 7. Histological localization of one dialysis site. (A). Schematic of a coronal cat brain section at 15.6 mm anterior to stereotaxic zero (modi®ed ...
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Effect of triiodothyronine (T<sub>3</sub>) augmentation of acute milnacipran administration on monoamine levels: an in vivo microdialysis study in rats
... The animals were divided into two groups. Control group rats were given the vehicle subcutaneously once daily in the morn- ing for 7 days and the T 3 group rats were given T 3 0.1 mg/kg or 0.2 mg/kg subcutaneously once ...
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Is a positive intracutaneous test induced by penicillin mediated by histamine? A cutaneous microdialysis study in penicillin-allergic patients
... performed microdialysis as described by Petersen et al. [18]. The microdialysis probes (EP Medical Aps ® , Copenhagen, Denmark) were semipermeable, linear, and equipped with a guide ...to probe ...
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Enhanced transdermal delivery of evodiamine and rutaecarpine using microemulsion
... C. Probe insertion was accomplished with a hypodermic needle, which served as a guide ...The microdialysis probe was then inserted through the guide cannula, which was then retracted to expose the ...
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In vitro microdialysis membrane efficiency of broad-spectrum antibiotics in combination and alone
... Three microdialysis probes (CMA 60 microdialysis cath- eters; CMA Microdialysis AB, Solna, Sweden), with mem- brane lengths of 30 mm and a molecular mass cutoff of 20 kDa, were connected to a ...
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Bench to bedside review: Microdialysis in intensive care medicine
... a microdialysis probe into the intestinal wall is not feasible for clinical ...Using microdialysis, Ungerstedt and colleagues [39] investigated local and regional gastro- intestinal ischemia caused ...
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Evaluation of psoralen ethosomes for topical delivery in rats by using in vivo microdialysis
... A microdialysis probe was implanted in the dermis, and the active dialysis window was placed immediately below the site of topical drug ...The probe was continu- ously perfused with ethanol solution ...
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“APPLICATION OF MICRODIALYSIS IN PRE-CLINICAL DRUG RESEARCH AND DEVELOPMENT” by Shabnam N Sani, Alain Stricker-Krongrad, United States of America.
... of microdialysis sampling has been in the examination of blood-brain barrier (BBB) transport and brain distribution of ...a microdialysis probe into the ...during microdialysis experiments was ...
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The proteome of human brain microdialysate
... Flexible microdialysis probes with a formal cut-off level of 20 kDa (membrane diameter ...CMA Microdialysis, Solna, Sweden) and an intracranial pressure measuring device (Spiegelberg, Hamburg, Germany) were ...
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Roots eye view: using microdialysis and microCT to non destructively map root nutrient depletion and accumulation zones
... contrast, microdialysis provides a non ‐ invasive, continuous method for sampling available nutrients in the ...position microdialysis probes at known distances from the roots and then measured the ...
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Role of vascular alpha 2 adrenoceptors in regulating lipid mobilization from human adipose tissue
... The role of alpha-2 adrenoceptors in lipid mobilization and blood flow was investigated in situ using microdialysis of subcutaneous adipose tissue in nonobese healthy subjects.. The alph[r] ...
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Evaluation of the Effects of Corticosteroids on Histamine Release by ex Vivo Cutaneous Microdialysis
... lumen probe in proportion to a concentration gradient ...and microdialysis for the skin absorption of salicylic acid and showed that the permeation profiles of salicylic acid determined by the both methods ...
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Skin microdialysis: methods, applications and future opportunities—an EAACI position paper
... the probe to elicit a wheal that develops across the probe. Experimentally, the impact of treatment on mediator release can be studied and compared to placebo treat- ment. While SMD is well suited for ...
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Liquid Crystalline Nanoparticles as an Ophthalmic Delivery System for Tetrandrine: Development, Characterization, and In Vitro and In Vivo Evaluation
... The purpose of this study was to develop novel liquid crystalline nanoparticles (LCNPs) that display improved pre-ocular residence time and ocular bioavailability and that can be used as an ophthalmic delivery system for ...
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Intraperitoneal lactate/pyruvate ratio and the level of glucose and glycerol concentration differ between patients surgically treated for upper and lower perforations of the gastrointestinal tract: a pilot study
... a microdialysis catheter was placed into the peritoneal cavity by use of a splittable introducer (Flocare Jejunokath ® , Nutricia, Erlangen, ...The microdialysis catheter was fixated to the skin to avoid ...
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The feasibility study of transnasopharyngeal esophagus echocardiography in the ultrasonic diagnosis
... TNPEE is a new technique developed by referring to transnasogastric endoscopy technology. Hospitals that have reported the technology in China are few, and there is no relevant information and experience for reference. ...
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Demonstration of an in vivo functional beta 3 adrenoceptor in man
... With the microdialysis method we compared the effects of the selective adrenergic agonists dobutamine 13,-selective, terbutaline /32-selective, and CGP 12177 663-selective on lipolysis a[r] ...
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In situ microdialysis in bone tissue Stimulation of prostaglandin E2 release by weight bearing mechanical loading
... cannot be elucidated from this experiment. The duration of lo- cal analgesia limits the time span of microdialysis in human bone in vivo. None of the investigated females had any signifi- cant pain after the ...
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