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Microvascular permeability

Quantitative Measurement of Microvascular Permeability in Human Brain Tumors Achieved Using Dynamic Contrast enhanced MR Imaging: Correlation with Histologic Grade

Quantitative Measurement of Microvascular Permeability in Human Brain Tumors Achieved Using Dynamic Contrast enhanced MR Imaging: Correlation with Histologic Grade

... 13.7%. Permeability values ranged from 2 ...the permeability values of specific tumors from different grades, differences in the mean were statistically ...and microvascular permeability in ...

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Microvascular permeability during experimental human endotoxemia: an open intervention study

Microvascular permeability during experimental human endotoxemia: an open intervention study

... in microvascular per- meability, suggesting a causal relationship ...in microvascular permeability, sustained high cytokine levels are apparently not mandatory for the develop- ment of ...

8

Discordance between microvascular permeability and leukocyte dynamics in septic inducible nitric oxide synthase deficient mice

Discordance between microvascular permeability and leukocyte dynamics in septic inducible nitric oxide synthase deficient mice

... The vascular endothelium is one of the earliest targets of injury in inflammatory states, ultimately contributing to organ dys- function and failure. Endothelial-directed recruitment and acti- vation of neutrophils at ...

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Dynamic, Contrast Enhanced CT of Human Brain Tumors: Quantitative Assessment of Blood Volume, Blood Flow, and Microvascular Permeability: Report of Two Cases

Dynamic, Contrast Enhanced CT of Human Brain Tumors: Quantitative Assessment of Blood Volume, Blood Flow, and Microvascular Permeability: Report of Two Cases

... mapping. Permeability variations across the tu- mor, however, were less consistent, perhaps because of differences between ionic and non-ionic contrast ...for microvascular quantifications are its ...

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Evaluation of Microvascular Permeability with Dynamic Contrast Enhanced MRI for the Differentiation of Primary CNS Lymphoma and Glioblastoma: Radiologic Pathologic Correlation

Evaluation of Microvascular Permeability with Dynamic Contrast Enhanced MRI for the Differentiation of Primary CNS Lymphoma and Glioblastoma: Radiologic Pathologic Correlation

... cular permeability parameters may be affected by several factors, including blood flow; blood volume; endothelial permeability; endothelial permeability surface area; and hydrostatic, interstitial, ...

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Measuring Elevated Microvascular Permeability and Predicting Hemorrhagic Transformation in Acute Ischemic Stroke Using First Pass Dynamic Perfusion CT Imaging

Measuring Elevated Microvascular Permeability and Predicting Hemorrhagic Transformation in Acute Ischemic Stroke Using First Pass Dynamic Perfusion CT Imaging

... Fig 1. A map of microvascular PS acquired from first-pass dynamic contrast-enhanced images over 60 seconds. There was a region of PS elevation encompassing the right insula cortex and portions of the right frontal ...

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-adrenoreceptor modulated FAK pathway induced by dexmedetomidine attenuates pulmonary microvascular hyper- permeability following kidney injury

-adrenoreceptor modulated FAK pathway induced by dexmedetomidine attenuates pulmonary microvascular hyper- permeability following kidney injury

... [37]. However, their role on pulmonary microvascular permeability has not been explored in the present study and warrants further study. Secondly, toxic substances and water accumulation in the circulation ...

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Unfractionated heparin and enoxaparin reduce high stretch ventilation augmented lung injury: a prospective, controlled animal experiment

Unfractionated heparin and enoxaparin reduce high stretch ventilation augmented lung injury: a prospective, controlled animal experiment

... increased microvascular permeability, neutrophil influx, lung PAI-1 mRNA expression, production of active PAI-1, and the deleterious effects were attenuated by low-dose unfraction- ated heparin or ...

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Original Article Expression of vascular endothelial growth factor and hypoxia-inducible factor 1α in rat traumatic lung injury

Original Article Expression of vascular endothelial growth factor and hypoxia-inducible factor 1α in rat traumatic lung injury

... Pulmonary microvascular permeability was detected by fluorescence ...pulmonary microvascular permeability, VEGF, and HIF-1α protein expression were significantly higher at 6, 24, 48, 72, and ...

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Thromboxane mediated hypertension and vascular leakage evoked by low doses of Escherichia coli hemolysin in rabbit lungs

Thromboxane mediated hypertension and vascular leakage evoked by low doses of Escherichia coli hemolysin in rabbit lungs

... In these lungs, the same features of dose-dependent potassium release, pressor response, and delayed increase in microvascular permeability were evoked by toxin doses approximating 1/25 [r] ...

9

Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury

Cell-free hemoglobin promotes primary graft dysfunction through oxidative lung endothelial injury

... on microvascular endothelial permeability ...endothelial permeability in dermal microvascular endothelial cells ...mesenteric permeability through actin cytoskeletal rearrangements and ...

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Prediction of Disease Free Survival in Patients with Squamous Cell Carcinomas of the Head and Neck Using Dynamic Contrast Enhanced MR Imaging

Prediction of Disease Free Survival in Patients with Squamous Cell Carcinomas of the Head and Neck Using Dynamic Contrast Enhanced MR Imaging

... The Ktrans parameter reflects a combination of tumor blood flow and microvascular permeability.19 Several studies have reported the use of DCE-MRI in patients with HNSCC for assessment o[r] ...

7

Chemokine expression during hepatic ischemia/reperfusion induced lung injury in the rat  The role of epithelial neutrophil activating protein

Chemokine expression during hepatic ischemia/reperfusion induced lung injury in the rat The role of epithelial neutrophil activating protein

... pulmonary microvascular permeability, lung neutrophil sequestration, and production of pulmonary-derived ENA-78; (b) passive immunization with neutralizing TNF antiserum resulted in a significant ...

9

Every allograft needs a silver lining

Every allograft needs a silver lining

... The development of chronic allograft rejection is based on the hypothesis that cumulative, time-dependent tissue injury eventually leads to a fibrotic response. In this issue of the JCI, Babu and colleagues found that ...

5

Systemic Cyotkines/Chemokines Contribute To Microvascular Dysfunction And Tissue Injury in Compartment Syndrome

Systemic Cyotkines/Chemokines Contribute To Microvascular Dysfunction And Tissue Injury in Compartment Syndrome

... The results of our study confirm that CS induces a systemic inflammatory response. Elevation of ICP for 2 hours resulted in a significant increase in serum TNF-α, coupled with the recruitment of activated leukocytes, and ...

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adrenoceptor protects human pulmonary microvascular endothelial cells from TNF-α induced hyper-permeability

adrenoceptor protects human pulmonary microvascular endothelial cells from TNF-α induced hyper-permeability

... Taken together, to our best knowledge, this was the first study that investigated the con- flicting conclusions about the effects of α 2 AR on inflammation and organ injuries based on treatment with α 2 AR agonists and ...

9

Regulation of β-Adrenergic Receptor Trafficking and Lung Microvascular Endothelial Cell Permeability by Rab5 GTPase

Regulation of β-Adrenergic Receptor Trafficking and Lung Microvascular Endothelial Cell Permeability by Rab5 GTPase

... These values were significantly higher than those in the control group (78.1 ± 8.9 and 69.5 ± 9.6 ng/ml, respectively; P<0.01). The LPS-induced increase in the BSA diffusion coefficient was attenuated to 204.2 ± 17.8 ...

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Hantavirus Infection Induces the Expression of RANTES and IP-10 without Causing Increased Permeability in Human Lung Microvascular Endothelial Cells

Hantavirus Infection Induces the Expression of RANTES and IP-10 without Causing Increased Permeability in Human Lung Microvascular Endothelial Cells

... rus-infected microvascular endothelial cells, resulting in the enhanced expression of the chemokines RANTES and ...vascular permeability in HFRS and ...of microvascular endothelial cells results in ...

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Study on the Critical Production Calculation Method of the Water Flooding Reservoir with Gas Cap

Study on the Critical Production Calculation Method of the Water Flooding Reservoir with Gas Cap

... As shown in Figure 4, for horizontal wells, when the water cut is the same, the critical production increases with the increment of the horizontal permeability and the ratio of vertical permeability to ...

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Molecular Profile of Tumours with an Oligodendroglial Morphology: Clinical Relevance

Molecular Profile of Tumours with an Oligodendroglial Morphology: Clinical Relevance

... 20 Photomicrograph of anaplastic oligodendroglioma with microvascular proliferation - low power view 69 21 Photomicrograph of anaplastic oligodendroglioma with microvascular proliferatio[r] ...

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