miR-1
Suppression of the biological activity of neuroglioma cells by down-regulation of miR-1.
... Fetal bovine serum (FBS) was purchased from Hyclone (Logan, UT, USA). Opti Minimum Essential Medium (MEM) and Roswell Park Memorial Institute (RPMI) 1640 media were purchased from Gibco (Grand Island, NY, USA). ...
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miR-1 inhibits the proliferation of breast cancer stem cells by targeting EVI-1
... of miR-1 on EVI-1 expression, we evaluated the expression of EVI-1 in transfected ...in miR-1 overexpressing BCSCs. However, EVI-1 expression was increased upon ...
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Transcription factor NRF2 regulates miR 1 and miR 206 to drive tumorigenesis
... that miR-1 and miR-206 miRNAs target 3 key genes of the PPP and 1 gene associated with carbohydrate/lipid metabo- lism — glycerol-3-phosphate dehydrogenase (GPD2) (Figure ...phosphate. ...
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Original Article The potential value of miR-1 and miR-374b as biomarkers for colorectal cancer
... for miR-1 in colorectal cancer, controlling MET expression through a feedback ...of miR-1 and increase of MACC1 contributes to MET overexpression and the metastatic behavior of colon cancer ...
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MALAT1 silencing suppresses prostate cancer progression by upregulating miR-1 and downregulating KRAS
... and miR-1, wild-type MALAT1 reporter containing predicted binding sites of miR-1 and mutant- type MALAT1 reporter with mutant binding sites of miR-1 was ...in ...
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Three novel serum biomarkers, miR-1, miR-133a, and miR-206 for Limb-girdle muscular dystrophy, Facioscapulohumeral muscular dystrophy, and Becker muscular dystrophy
... of miR-1, miR- 133a, and miR-206 levels in serum of DMD patients resulted from inclusion of these miRNAs within exosome, we separated serums from patients and controls into exo- some and ...
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Original Article miR-1 and miR-145 act as tumor suppressor microRNAs in gallbladder cancer
... of miR-1 and miR-145 by transfecting cells with pre-miR miRNA precursor ...of miR-1 in transfected cells was monitored through the expression of twinfilin actin-binding protein ...
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miR-1/206 downregulates splicing factor Srsf9 to promote C2C12 differentiation
... either miR-206 (2x206) or miR-1 (2x1) (data not ...of miR-1/206 on the 2x206 and 2x1 con- structs as well as on the 3′ UTR of Ccnd1, previously identified as a miR-206 target in ...
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Role of miR-1 and miR-133a in myocardial ischemic postconditioning
... myocardial-specific miR-1 and miR-133a play an important role in IPost protection against myocardial IR injury by regulating apoptosis-related ...of miR-1 and miR-133a in IPost ...
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CirculatingMiR-10b, MiR-1 and MiR-30a Expression Profiles in Lung Cancer: Possible Correlation with Clinico-pathologic Characteristics and Lung Cancer Detection
... evaluate miR-10b, miR-1 and, miR-30a in the plasma samples of lung cancer patients to confirm any possible relevance in the early detection of lung ...smokers. ...
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miR 1 and miR 206 regulate angiogenesis by modulating VegfA expression in zebrafish
... that miR-1 and miR-206 negatively regulate angiogenesis during zebrafish ...that miR-1/206 directly regulate the levels of Vascular endothelial growth factor A (VegfA) in muscle, ...
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IL-10Rα expression is post-transcriptionally regulated by miR-15a, miR-185, and miR-211 in melanoma
... of miR-15α ( IL-10Rα 3′-UTR wild 1), miR- 185 (IL-10Rα 3′-UTR wild 2), miR-211 ( IL-10Rα 3′- UTR wild 3) or covering all the three miRNA side sites (IL-10Rα 3′-UTR ...of miR-15a (pGL3- ...
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MiR-344b-1-3p targets TLR2 and negatively regulates TLR2 signaling pathway
... of miR-344b-1-3p in COPD AMs was significantly enhanced compared to that in the control ...between miR-344b-1-3p and TLR2 was con- firmed as ...that miR-344- b-1-3p played an ...
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Original Article Circulating miR-665 and miR-30c-1-3p, the candidate markers of congestive heart failure with qi-deficiency-blood-stasis syndrome
... of miR-133 and miR-208b were elevated at acute phase of ACS and highly relat- ed to mortality over six months ...Increased miR-155 resulted in macrophage infiltration and enhanced atherogenesis in ...
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Circ_0027599/PHDLA1 suppresses gastric cancer progression by sponging miR-101-3p.1
... cancers. In oral cancer, PHLDA1 was overexpressed, which acted as an apoptosis suppressor and was associ- ated with advanced clinical stage of oral cancer [4]. How- ever, in oral squamous cell carcinoma, the expression ...
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Evaluation of miR-141, miR-200c, miR-30b Expression and Clinicopathological Features of Bladder Cancer
... Total RNA including miRNAs was isolated from about 50 mg tissue samples by applying TRIZOL reagent (Invitrogen, Germany) according to the manufacturer's protocol. The extracted RNA was dissolved in 20- 50 µ l RNase- free ...
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Associations between microRNA (miR-25, miR-32, miR-125, and miR-222) polymorphisms and recurrent implantation failure in Korean women
... Many miRNAs have important roles in diverse cellular processes [23], including the regulation of molecular pathways, adhesive junctions, and cell adhesion in pa- tients with RIF [5]. MicroRNA-181 inhibits embryo im- ...
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Original Article Role of polymorphisms in miR-146a, miR-149, miR-196a2 and miR-499 in the development of ovarian cancer in a Chinese population
... between miR-146a (rs2910164), miR-149 (rs2292832), miR-196a2 (rs11614913) and miR-499 (rs3746444) polymorphisms and development of ovarian cancer in a Chinese ...the miR-146a, ...
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Expression of miR-15b, miR-29b, miR-219 and miR-222 microRNAs in rats with focal cerebral ischemia submitted to physical exercise
... Little is known about the role of exercise in cerebrovascular diseases, especially in the process of cerebral ischemia and regulation of neurotransmitter receptors. Therefore, elucidating the role of microRNAs in the ...
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miR-376a inhibits breast cancer cell progression by targeting neuropilin-1 NR
... that miR-376a was enriched in RNAs retrieved from Luc-NRP-1-wt-overexpressed cells compared with Luc-NRP-1-mut-overexpressed or control cells (Figure 2F); these results supported that NRP-1 ...
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