miR-133a
MiR-133a is downregulated in non-small cell lung cancer: a study of clinical significance
... of miR- 133a, including EGFR. Putative miR-133a binding sites of EGFR have also been identified by computational algorithms from several online miRNA-target gene predic- tion softwares, ...
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Methylation-mediated silencing of miR-133a-3p promotes breast cancer cell migration and stemness via miR-133a-3p/MAML1/DNMT3A positive feedback loop
... of miR-133a-3p expression and its tumor suppressor activity in various human cancers are gradually reported ...for miR-133a-3p dysregulation in breast cancer have not been ...suppressor-type ...
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Original Article Identification of miR-133a-3p-expression signature and probable mechanism in lung squamous cell carcinoma: Insights from integrated analysis
... USA). miR- 191 (Forward: 5’-CAACGGAAUCCCAAAAGCAG- CU) and miR-103 (Forward: 5’-AGCAGCAUUG- UACAGGGCUAUGA) were used as control miR- NAs for stable expression according to Norm- Finder and ...for ...
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Original Article Effects and mechanisms of miR-133a on invasion and migration of gastric cancer cells MKN28
... of miR-133a on the invasion and migration of gastric cancer cells and to explore the mechanisms contained within ...of miR-133a in gastric cancer cell lines with high metastatic BGC-823 lines, ...
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Role of downregulated miR-133a-3p expression in bladder cancer: a bioinformatics study
... A total of 14 online prediction software, miRWalk, Microt4, miRanda, mirbridge, miRDB, miRMap, miRNAMap, Pictar2, PITA, RNA22, RNAhybrid, Targetscan, mirTarbase and PolymiRTS, were employed to collect the target genes of ...
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<p>Tanshinone IIA Ameliorates Progression of CAD Through Regulating Cardiac H9c2 Cells Proliferation and Apoptosis by miR-133a-3p/EGFR Axis</p>
... assay, miR-133a-3p mimics or miR-NC mimics and repor- ter plasmids (pGL3-EGFR-WT or pGL3-EGFR-MUT) were co-transfected into 293T cells by lipofectamine 2000 (Life Technologies, Darmstadt, ...
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Original Article Long non-coding RNA UPAT promotes cell proliferation via regulating the miR-133a/ IGF1R axis in colorectal cancer
... to miR-133a expression in colorectal cancer tissues and ...endogenous miR-133a and inhibit its ...and miR-133a overexpression in CRC cell lines led to cell proliferation and cell ...
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Original Article Down-regulation of miR-133a-3p in hepatocellular carcinoma tissues and its potential regulatory molecular mechanism: a study of qRT-PCR and bioinformatics analysis
... of miR-133a-3p in hepatocellular carcinoma (HCC) and to explore the underlying regulatory molecular ...of miR-133a-3p was detected by RT-qPCR and its associations with clinicopathological ...
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Original Article Serum miR-133a is down-regulated and associated with the diagnosis of patients with gastric cancer
... of miR-133a and assess the diagnostic val- ue of it in gastric cancer ...serum miR-133a was examined by real-time quantitative reverse transcription polymerase chain reaction ...between ...
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Original Article Clinical significance of miR-133a and miR-206 in pregnant women with preeclampsia and correlation with pregnancy outcomes
... Moreover, miR-206 plays key roles in tumors and cardiovascular diseas- es by regulating cell apoptosis, proliferation, and differentiation, as well as angiogenesis ...of miR-133a and miR-206 ...
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RETRACTED ARTICLE: Down-regulation of miR-133a and miR-539 are associated with unfavorable prognosis in patients suffering from osteosarcoma
... the miR-133a expression was significantly decreased in clinical osteosarcoma tissues compared to adjacent normal bone ...of miR-539 was decreased in clinical osteo- sarcoma tissues as compared to ...
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Downregulation of miR-133a-3p promotes prostate cancer bone metastasis via activating PI3K/AKT signaling
... of miR-133a-3p, in which only EGFR, FGFR1, IGF1R and MET were targeted by miR-133a-3p in PCa ...silencing miR-133a-3p in PCa ...that miR-133a-3p represses AKT ...
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Original Article Short-term vagal nerve stimulation improves chronic heart failure via miR-133a-3p upregulation in a rat model
... 11 miR- NAs showed significantly al- tered ...rno- miR-350, rno-miR-138-1-3p, rno-miR-3571, rno-miR-129- 1-3p, rno-miR-133a-3p, and rno-miR-133b-3p) were sup- ...
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Novel role of miR-133a-3p in repressing gastric cancer growth and metastasis via blocking autophagy-mediated glutaminolysis
... the miR-133a-3p in- duced inhibition on GC cell proliferation,invasion and ...of miR-133a-3p on autophagy. Overexpression of miR-13 3a-3p successfully blocks the serum ...
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Role of miR-1 and miR-133a in myocardial ischemic postconditioning
... myocardial-specific miR-1 and miR-133a play an important role in IPost protection against myocardial IR injury by regulating apoptosis-related ...of miR-1 and miR-133a in IPost ...
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miR-133a Regulates Vitamin K 2,3-Epoxide Reductase Complex Subunit 1 (VKORC1), a Key Protein in the Vitamin K Cycle
... with miR-133a precursor or SCR, 3′UTR firefly luciferase reporter plasmid (500 ng/well) and 50 ng/well of renilla luciferase con- trol plasmid (pRL-TK; Promega, Madison, WI, ...
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A circular transcript of ncx1 gene mediates ischemic myocardial injury by targeting miR-133a-3p
... of miR-133a-3p. (C) Biotin-labeled miR-133a-3p mimics or control mimics were transfected into H9c2 ...pulled-down miR-133a-3p and U6 by circNCX1 probe or control probe were ...
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ZEB1-AS1/miR-133a-3p/LPAR3/EGFR axis promotes the progression of thyroid cancer by regulating PI3K/AKT/mTOR pathway
... sponges miR-133a-3p. a Potential lncRNAs targeting miR-133a-3p were ...with miR-133a-3p were ...and miR-133a-3p was predicted by ...
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miR-133a function in the pathogenesis of dedifferentiated liposarcoma
... RNA was isolated using a GeneJET RNA Purification Kit (Thermo Fisher Scientific, Waltham, MA, USA) and real-time PCR was performed using the StepOne Plus Detection System (Applied Biosystems). RNA concen- tration and ...
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CXCL12/CXCR4 promotes inflammation-driven colorectal cancer progression through activation of RhoA signaling by sponging miR-133a-3p
... Notably, miR-133a-3p was found to be significantly decreased in HCT116 cells overexpressing CXCR4 by miRNA ...sequencing. miR-133a-3p was proved to target RhoA, which is involved in ...
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