MiR-181b
LncRNA DLX6-AS1 promoted cancer cell proliferation and invasion by attenuating the endogenous function of miR-181b in pancreatic cancer
... targeted miR‑181b in pancreatic cancer cells We used the DIANA tools to predict the potential tar- gets of DLX6-AS1 and found that miR-181b contain the complementary binding site of ...with ...
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miR-181b as a therapeutic agent for chronic lymphocytic leukemia in the Eµ-TCL1 mouse model
... administration, miR-181b or negative control mimics (Axolabs, Germany) were assembled in a complex with in vivo jetPEI (Polyplus-Transfection SA, France), using a nitrogen-to-phosphate ratio of 8, as ...
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Assessment of miR-181b-5p, miR-23a-3p, BCL-2, and IL-6 in Peripheral Blood Mononuclear Cells of Autistic Patients; Likelihood of Reliable Biomarkers
... the miR expression profile of ASD patients; especially the miR-23a-3p and miR- 181b-5p which are mainly found in both circulation and brain ...22,23 miR-23a is upregulated in brain ...
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Association between MEG3/miR-181b polymorphisms and risk of ischemic stroke
... [26–28, 30]. Altered expression of cerebral MEG3 was observed both in vitro and in vivo, activating p53 to mediate ischemic neuronal death in stroke [27, 28]. Downregulation of MEG3 can protect against ischemic damage ...
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Effects of Panax notoginseng saponins on severe acute pancreatitis through the regulation of mTOR/Akt and caspase 3 signaling pathway by upregulating miR 181b expression in rats
... Methods: A rat model of severe acute pancreatitis (SAP) was established in rats induced with taurocholate. Panax notoginseng saponins was firstly administered in the treatment group via intravenous injection. After 2 h, ...
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Vascular miR-181b controls tissue factor-dependent thrombogenicity and inflammation in type 2 diabetes
... inflammation, miR-181b lev- els did not correlate with blood glucose or HbA1c in our ...that miR- 181b expression in HMEC-1 and human umbilical vein endothelial cells (HUVEC) is reduced by ...
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MiR-181b suppress glioblastoma multiforme growth through inhibition of SP1-mediated glucose metabolism
... by miR-181b ...of miR-181b on proliferation in GBM cells. Meanwhile, miR-181b inhibited the cell pro- liferation of U87 and U251 ...that miR-181b might regulate ...
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miR-181b/Notch2 overcome chemoresistance by regulating cancer stem cell-like properties in NSCLC
... of miR-181b remained relatively high in stage I and II tumours but decreased in stage III tumours ...relative miR-181b and Notch2 mRNA ex- pression in NSCLC tissues from patients (p = ...Lower ...
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<p>Triptolide Inhibits the Proliferation of HaCaT Cells Induced by IL22 via Upregulating miR-181b-5p</p>
... of miR-181b-5p (Figure ...that miR-181b-5p agomir sup- pressed the luciferase activity of psiCHECK-2-E2F5-WT (Figure ...of miR-181b-5p signi fi cantly increased the level of ...
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<p>LncRNA CCAT1 Promotes Colorectal Cancer Tumorigenesis Via A miR-181b-5p/TUSC3 Axis</p>
... of miR-181b-5p seed sequence frag- ment was cloned into ...and miR-181b-5p mimics or mimics control using Lipofectamine ® 2000 Reagent for 48 ...with miR- 181b-5p mimics or ...
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Original Article Overexpressed miR-181b promotes nerve cell damage via inhibiting cell proliferation but inducing cell apoptosis during ischemic cerebral stroke
... of miR-181b in nerve cells during ...that miR-181b was highly expressed in nerve cell under oxygen glucose deprivation (OGD) condition than that in normal cells; B: After cells were treated ...
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Osteocyte-derived exosomes induced by mechanical strain promote human periodontal ligament stem cell proliferation and osteogenic differentiation via the miR-181b-5p/PTEN/AKT signaling pathway
... study, miR-181b-5p was identified in Exosome-MS ...that miR-181 is mainly involved in the progression of cancer ...cancer, miR-181 regulated vascular cell adhesion molecule-1 (VCAM-1) ...
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MiR-181b: new perspective to evaluate disease progression in chronic lymphocytic leukemia
... hand, miR-181b was apparently worse predictor of the stable disease compared to the other 2 prognostic markers, in that, among sequential specimens from this patient category, the properties were observed ...
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Original Article Down-regulation of miR-181b promotes apoptosis by targeting CYLD in thyroid papillary cancer
... miR-181b was significantly higher in thyroid PTCs compared with normal thyroid tissue [12, 13] and our experiment of microRNA-array analysis also demonstrated that miR-181b was higher in ...
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MicroRNA-181b regulates endotoxin tolerance by targeting IL-6 in macrophage RAW264.7 cells
... whether miR-181b also up-regulated the expres- sion of IL-6 during LPS induced ...with miR-181b inhibitors, and then followed by secondary LPS ...with miR- 181b inhibitors ...
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Original Article MicroRNA-181b promotes osteosarcoma cell proliferation, invasion and migration in vitro via targeting RASSF8
... that miR-181b can promoted OS proliferation, invasion and migra- tion through down regulating ...whether miR-181b involved in these pathways in OS should be investigated in the ...suggested ...
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Original Article Role of peripheral blood microRNA-181b in acute vascular rejection after renal transplantation
... Peripheral blood (5 mL) of patients from differ- ent groups was extracted at different time points (preoperatively, at 1 week, 2, 3, and 4 weeks postoperatively). And miRNA extraction was performed following the ...
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Original Article MicroRNA 181b promotes vascular smooth muscle cells proliferation through activation of PI3K and MAPK pathways
... by the Institutional Animal Care and Use Committee of China Medical University. 250- 300 g male Sprague-Dawley rats were pur- chased from the Medical Experimental Animal Center of China Medical University and the common ...
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Taming endothelial activation with a microRNA
... Inflammation plays an essential role in vascular pathologies, including those associated with sepsis and atherosclerosis. Identifying negative regulators of inflammatory signaling pathways may provide novel therapeutic ...
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MicroRNA 181b regulates NF κB–mediated vascular inflammation
... whether miR-181b regulates NF-κB translocation in vivo, miR-181b was systemically administered by tail-vein injection, and mice were challenged with or without ...delivered ...
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