miR-199a-3p
The hypoxia-related microRNA miR-199a-3p displays tumor suppressor functions in ovarian carcinoma
... disease. miR-199a- 3p is significantly down-regulated in ovarian cancer and its restoration has been reported to be linked with the inhibition of PAK4, CD44, and mTOR [14, 15, and 16], all of which ...
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miR-199a-3p targets stemness-related and mitogenic signaling pathways to suppress the expansion and tumorigenic capabilities of prostate cancer stem cells
... potential miR-199a-3p binding site in the c-MYC CDS (Supplementary Figure ...that miR-199a-3p partially targeted c-MYC in PC3 cells (Figure ...the ...
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Original Article MiR-100-5p, miR-199a-3p and miR-199b-5p induce autophagic death of endometrial carcinoma cell through targeting mTOR
... by miR- 100-5p, miR-199a-3p and miR-199b-5p mim- ...that miR-100-5p, miR-199a- 3p and miR-199b-5p may have influence on autophagy by targeting mTOR, ...
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The miR-199a-3p regulates the radioresistance of esophageal cancer cells via targeting the AK4 gene
... Esophageal cancer (EC) is the eighth most commonly occurred cancer worldwide. It has proven to be one of the most difficult malignancies to cure [14, 15]. To date, the chemotherapy or chemoradiotherapy are still the ...
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<p>Down-Regulation of ZEB1 by miR-199a-3p Overexpression Restrains Tumor Stem-Like Properties and Mitochondrial Function of Non-Small Cell Lung Cancer</p>
... is miR-199a-3p (or miR-199b-3p). miR199a-3p and miR-199b-3p are equiva- lent sequences of 22 ...including miR-199a-3p and other 4 microRNAs ...
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Downregulation of miR-199a-3p mediated by the CtBP2-HDAC1-FOXP3 transcriptional complex contributes to acute lung injury by targeting NLRP1
... of miR-199a-3p because we identified two potential sites (Figure ...of miR-199a-3p (-31 to -37 region instead of -960 to -966 region) was significantly increased in ...
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<p>LncRNA LINC01140 Inhibits Glioma Cell Migration and Invasion via Modulation of miR-199a-3p/ZHX1 Axis</p>
... that miR-199a-3p suppressed glioma cell proliferation through the regulation of the AKT/ mTOR signaling ...of miR-199a-3p were down- regulated in glioma cell ...sponge ...
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Demethylation by low-dose 5-aza-2′-deoxycytidine impairs 3D melanoma invasion partially through miR-199a-3p expression revealing the role of this miR in melanoma
... upon miR-199a-3p trans- fection were crossed with gene list of its predicted targets genes by five different softwares (DIANAmT, miRanda, miRDB, miRWalk and TargetScan) on the website: http:// ...of ...
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miR-199a-3p inhibits cell proliferation and induces apoptosis by targeting YAP1, suppressing Jagged1-Notch signaling in human hepatocellular carcinoma
... whether miR-199a-3p targets YAP1, and downregulates Jagged1 to inhibit proliferation and pro- mote apoptosis of HCC cells, we firstly upregulated miR-199a-3p and downregulated ...
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Suppressing miR-199a-3p by promoter methylation contributes to tumor aggressiveness and cisplatin resistance of ovarian cancer through promoting DDR1 expression
... of miR-199a-1 ...decreased miR-199a-3p and upregulation of DDR1 in the ovarian cancer specimens ...of miR-199a-3p significantly increased while DDR1 were ...
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Review Article Dysregulated microRNAs with prognostic significance in human hepatocellular carcinoma: a study based on high-throughput microarray
... of miR-199a-3p in HCC tissues was ...that miR-199a-3p could be a novel serum diagnostic biomarker for HCC ...low miR-199a-3p expression was related with the ...
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Polymeric nanoparticle-based delivery of microRNA-199a-3p inhibits proliferation and growth of osteosarcoma cells
... of miR-199a-3p into osteosarcoma cells using a dextran nanoparticle-based delivery ...The miR-199a-3p-encapsulated nanoparticles showed high miR transfection efficiency, ...
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MiR-199a-modified exosomes from adipose tissue-derived mesenchymal stem cells improve hepatocellular carcinoma chemosensitivity through mTOR pathway
... of miR- 199a-3p. MiR-199a-3p-mediated regulation of these genes has been shown to correlate with various types of cancer, including HCC ...with miR-199a-3p ...
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Altered expression of DLG1-AS1 distinguished papillary thyroid carcinoma from benign thyroid nodules
... Plasma miR-199a-3p was specifically downregulated in PTC and was positively correlated with DLG1-AS1 in ...of miR-199a-3p in plasma derived from 3 groups of participants (PTC, ...
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Characterization of miRNA-regulated networks, hubs of signaling, and biomarkers in obstruction-induced bladder dysfunction
... Testing the mRNA and miRNA signatures of bladder dysfunction states in a blinded study. The 3-mRNA and 3-miRNA signatures of urodynamically defined bladder states were tested in an independent blinded fol- low-up study ...
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Serum microRNA-199a/b-3p as a predictive biomarker for treatment response in patients with hepatocellular carcinoma undergoing transarterial chemoembolization
... Their miR PCR arrays, per- formed on cells from two ovarian cancer cell lines (CaOV3 and RMUG-S), revealed that miR-199a-3p was downregu- lated under ...presses miR-199a-5p ...
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Original Article miR-199a-5p regulates the expression of metastasis-associated genes in B16F10 melanoma cells
... Thus, miR-199a-5p exhibits mul- tiple biological functions and tissue ...The miR-199a is highly expressed in melanoma exhibiting high invasive ability ...of miR-199a is increased ...
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MicroRNA-214-3p inhibits proliferation and cell cycle progression by targeting MELK in hepatocellular carcinoma and correlates cancer prognosis
... that miR-214-3p is corre- lated with tumor onset and progression ...that miR-214-3p is downregulated in HCC tis- sues and closely related to fibrotic stages [11, 12]; how- ever, the biological ...
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mir-101-3p is a key regulator of tumor metabolism in triple negative breast cancer targeting AMPK
... of mir-101 was reported in several malignancies, including glioma [11], liver [12], prostate [13], and breast cancer ...implied mir-101 to be a tumor suppressor. Mir-101 directly targets enhancer of ...
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<p>Effect of LINC00657 on Apoptosis of Breast Cancer Cells by Regulating miR-590-3p</p>
... and miR-590-3p in each cell line were ...The miR-590-3p-inhibitor (inhibition sequence), miR-590-3p-mimics (over-expression sequence), miR-negative control ...
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