MIR-2
MiR-26a and miR-144 inhibit proliferation and metastasis of esophageal squamous cell cancer by inhibiting cyclooxygenase-2
... of miR-26a and miR-144 in ESCC clinical tissues and cell lines were investigated by ...in miR-26a and miR-144 expression in ESCC was found by a comparison between 30 pairs of ESCC tumor and ...
14
<em>MiR-203</em> is involved in the laryngeal carcinoma pathogenesis via targeting VEGFA and Cox-2
... with miR-203 mimic or inhibitor, with sequence scrambled single-strand or double-strand short rna as ...the miR-203 mimic or inhibitor with scramble rna as ...
9
Original Article Decreased expression of miR-218 is associated with poor prognosis in patients with colorectal cancer
... of miR- 218 from tissue sample was normalized to the endogenous reference gene RNU6, whereas the cel-miR-39 was used as the reference con- trol for serum samples ...
8
Original Article MiR-218 inhibits HMGB1-mediated autophagy in endometrial carcinoma cells during chemotherapy
... accumulation of LC3 puncta in EC cells was sig- nificantly higher in Tax treatment groups (Figure 3A) and significantly high levels of LC3-I to LC3- II conversion and Beclin1 expression were also observed in the EC cells ...
10
MicroRNA miR-21 Attenuates Human Cytomegalovirus Replication in Neural Cells by Targeting Cdc25a
... of miR-21 overexpression on HCMV gene expres- sion and genome replication manifest at early times of infection and are largely gone by 96 hpi ...ectopic miR-21 can in time be overcome by a counteracting ...
13
Kaposi's Sarcoma-Associated Herpesvirus Encodes a Mimic of Cellular miR-23
... miRNAs miR-155 and miR-142-3p. Two addi- tional KSHV miRNAs, miR-K3 ⴙ 1 and miR-K3, share perfect and offset 5= homology with cellular miR-23, ...causes miR-K3ⴙ1 expression in a ...
10
Original Article Screening for aberrantly-expressed microRNAs in peripheral blood leukocytes from silicosis patients
... including miR-181, miR-19a, miR-20a, and ...these, miR-181a and miR-19a in peripheral blood white cells were identified as potential biomarkers of sili- cosis, combined with microarray ...
10
Decrease expression of microRNA-20a promotes cancer cell proliferation and predicts poor survival of hepatocellular carcinoma
... while miR-20a were found to be significantly up-regulated in colon adenocarcinoma [8] and gliomas ...that miR-20a may be a tis- sue specific microRNA. On the other hand, miR-20a has been shown to ...
10
Micro-ribonucleic acid 29b inhibits cell proliferation and invasion and enhances cell apoptosis and chemotherapy effects of cisplatin via targeting of DNMT3b and AKT3 in prostate cancer
... was miR-29b-forward 5 ′ -GGGTAGCACCATTTGAAATC-3 ′ , miR-29b-reverse 5 ′ -TTTGGCACTAGCACATT-3 ′ , U6- forward 5 ′ -CTCGCTTCGGCAGCACA-3 ′ , and U6-reverse 5 ′ -AACGCTTCACGAATTTGCGT-3 ′ ...
9
MicroRNA-23a Participates in Estrogen Deficiency Induced Gap Junction Remodeling of Rats by Targeting GJA1
... NC, miR-23a, AMO-23a as well as miR-23a plus AMO-23a by X-treme GENE siRNA transfection reagent ...from miR-23a or AMO-23a sequence. miR-23a mimics (sense: 5’-AUCACAUUGCCAGGGAUUUCC-3’, an- ...
14
miR-34a promotes bone regeneration in irradiated bone defects by enhancing osteoblastic differentiation of mesenchymal stromal cells in rats
... conditions. miR-33-5p is a key factor in the development of osteopenia induced by mechanical unload- ing, and miR-33-5p-targeted treatment could alleviate the osteopenia ...[21]. miR-26a was ...
14
The roles of microRNA families in hepatic fibrosis
... that miR-200 family participates in fibrosis. A single injection of pre- miR-200b inhibits COLI expression level in renal fibrosis ...[46]. miR-200b inhibits the process of intestinal fibrosis ...
9
Prospective validation of microRNA signatures for detecting pancreatic malignant transformation in endoscopic-ultrasound guided fine-needle aspiration biopsies
... in miR-21, and miR-155 as biomarkers for pancreatic ...that miR-21 and miR-155 were up- regulated in ex vivo aspirates from surgical specimens of non-invasive IPMNs (n = 15), when compared to ...
14
Changes in microRNA expression profile in hippocampus during the acquisition and extinction of cocaine-induced conditioned place preference in rats
... and miR-26b is reported to negatively regulate brain-derived neurotrophic factor (BDNF) expression at post-transcriptional level ...as miR-181a, miR-124 and let-7b [7,8]. MiR-212 in the ...
10
Inhibition of miRNA-210 reverses nicotine-induced brain hypoxic-ischemic injury in neonatal rats
... underlying miR-210-mediated brain injury may be due to an alteration of its target ...that miR-210 has a potential binding site at 3’ UTR of gene encoding BDNF mRNA region (see the diagram in figure ...of ...
9
<p>Long Non-Coding RNA OIP5-AS1 Knockdown Enhances CDDP Sensitivity in Osteosarcoma via miR-377-3p/FOSL2 Axis</p>
... Recent studies uncovered that OIP5-AS1 played vital roles in tumor progression and chemoresistance. For exam- ple, Wang et al indicated that the high expression of OIP5- AS1 contributed to tumor progression in bladder ...
14
Temozolomide resistance in glioblastoma occurs by miRNA-9- targeted PTCH1, independent of sonic hedgehog level
... CCL64 cells were stably transfected with a reporter gene vector in which the 3′UTR was inserted downstream of luciferase (pPTCH-UTR-JM). Parallel cultures were transfected with vector alone. The stable transfectants were ...
12
The Role of miR-526b in COX-2 Mediated Human Breast Cancer Progression and Induction of Stem-Like Phenotype Via EP4 Receptor Signaling
... Previous work in our lab by Majumder et al. (2012) established that stable transfection and over-expression of the COX-2 gene in MCF-7 (ER+, HER2-, COX-2-) and SKBR-3 (ER-, HER2+, COX-2-) human ...
136
Comparing diagnostic and prognostic performance of two-gene promoter methylation panels in tissue biopsies and urines of prostate cancer patients
... of miR-34b/c and panel #2 genes associated with clinicopathological features of disease aggressiveness (prognostic grade group, CAPRA score, D’Amico’s risk classification), sug- gesting the ability to ...
11
Original Article MicroRNA-155 modulates the expression of pro-inflammatory cytokines in natural killer cells of rats exposed to chronic mild stress by regulation of ERK1/2 signaling pathway
... Twenty male Sprague-Dawley (SD) rats (45- days old) were obtained from Shanghai SLAC Laboratory Animal Co., Ltd., China. All the ani- mals were caged individually in an air-condi- tioned room with controlled temperature ...
8