miR-218
Original Article Decreased expression of miR-218 is associated with poor prognosis in patients with colorectal cancer
... of miR-218 expression in sera and tissues from CRC ...of miR-218, SLIT2 and SLIT3 were measured by quantitative reverse transcription PCR ...between miR-218 expression and ...
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<p>The Multifunction Of miR-218-5p-Cx43 Axis In Breast Cancer</p>
... that miR-218-5p enhanced chemore- sistance of gemcitabine in a breast cancer ...cell. miR-218-5p is down-regulated and acts as a tumor suppressor in various cancers such as nasopharyngeal ...
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<em>miR-218</em> overexpression suppresses tumorigenesis of papillary thyroid cancer via inactivation of PTEN /PI3K/AKT pathway by targeting Runx2
... of miR-218 in PTC progres- sion, K-1 and TPC-1 cells were transiently transfected with miR-218 mimic or ...of miR-218 expression was observed in K-1 and TPC-1 cells following ...
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Original Article MiR-218 suppresses osteosarcoma proliferation by down-regulating BMI1
... of miR-218 has been reported in human gliomas compared with normal brain tissue [18-20], and in this context miR-218 was shown to directly target IKK-beta [18], RTK [21] and CDK6 [22, 23], ...
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RETRACTED ARTICLE: Up-regulation of miR-130b expression level and down-regulation of miR-218 serve as potential biomarker in the early detection of human osteosarcoma
... of miR-130b and miR-218 expressions in OS patients and normal tissues and their relationship with clinicopathological features and survival in OS ...that miR-130b expression in tumor tissues ...
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MACC1 is post-transcriptionally regulated by miR-218 in colorectal cancer
... of miR-218 or the respective control-miR along with the SW480-empty vector ...of miR-218 expression and MACC1 expression was measured with qRT-PCR and Western blot analysis, ...
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MiR 218 produces anti tumor effects on cervical cancer cells in vitro
... of miR-218 in 3′-UTR frag- ment of IDO1 were predicted with reference to TargetScan website ...of miR-218 and IDO1 was verified by dual-luciferase reporter ...of miR-218 on the ...
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Original Article Co-regulation of miR-143, miR-218 and miR-338-3pin inhibits gastric cancer migration and invasion by targeting collagen type I
... that miR-143, miR-218, and miR-338-3p are all down-regulat- ed in gastric cancer, and the co-regulation of the three miRNAs may negatively regulate the metastasis and invasion of gastric ...
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MiR-218 regulates epithelial–mesenchymal transition and angiogenesis in colorectal cancer via targeting CTGF
... whether miR-218 is dysregulated in CRC cell lines, we evaluated its expression level by miRNA RT-PCR ...of miR-218 in several CRC cell lines, including SW480, SW620, HCT8, and HCT116 were ...
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A Slit/miR 218/Robo regulatory loop is required during heart tube formation in zebrafish
... of miR-218 morphants (n53) versus 8% of control embryos ...whole miR- 218 morphant embryos (data not shown), in situ hybridization suggested increased robo1 expression in the endocardium and ...
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Original Article MiR-218 suppresses cell progression by targeting APC in cervical cancer
... that miR-218 was abnormally expressed in several ...of miR-218 in the progression of cervical cancer ...of miR-218 in tissues and cells of CC; west- ern blot was used to detect ...
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Original Article Targeted regulation of miR-218 on BIRC5 for hepatocellular carcinoma apoptosis and proliferation
... Using HEK293 DNA as the template, full length fragment of 3’-UTR of BIRC5 gene was ampli- fied. PCR products were collected from agarose gel, and were ligated into pGL-3M luciferase reporter plasmid after enzymatic ...
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SMO ) gene as a functional target of miR-218, and found that SMO overexpression counteracts the chemosensitizing effects of miR-218. These findings suggest that miR-218
... of miR-218 in drug efflux from gastric cancer cells, we examined the ADM release index in SGC7901 cells transfect- ed with miR-218 mimic or negative ...with miR-218 mimic ...
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<p>MiR-218-5p Suppresses the Progression of Retinoblastoma Through Targeting NACC1 and Inhibiting the AKT/mTOR Signaling Pathway</p>
... that miR-218-5p can participate in tumor progression through multiple signaling ...pathways. MiR-218-5p was found to exert an anti-tumor effect through binding to EGFR in non-small cell lung ...
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Original Article miR-218 modulate hepatocellular carcinoma cell proliferation through PTEN/AKT/PI3K pathway and HoxA10
... with miR-218 mim- ics, miR-218 inhibitors or non-specific controls, cells were fixed by ice-cold methanol for 30 min and stained by Crystal violet for 10 ...
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Metastatic breast cancer cells overexpress and secrete miR 218 to regulate type I collagen deposition by osteoblasts
... secreted miR-218 in vivo, we injected EVs from MDA-231-miR-ctrl or MDA-231-miR-218 into NSG mice through the tail vein twice a week for 4 ...cancer-secreted miR-218 ...
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Antagonizing miR-218-5p attenuates Wnt signaling and reduces metastatic bone disease of triple negative breast cancer cells
... with miR-218-5p mimic, antimiR-218-5p inhibitor, or the non-targeting control and injected tumor cells into the tibiae of immunocompromised SCID ...when miR-218-5p mimic was delivered ...
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Review Article Expression of miR-218 in brain glioma and its relationship with AKT/mTOR signal pathway
... of miR-218 in tumor and adjacent tissues of all 41 brain glio- ma ...of miR-218 in tumor tissues was sig- nificantly lower than that of adjacent tissues ...1B, miR-218 expression ...
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Original Article MiR-218 inhibits HMGB1-mediated autophagy in endometrial carcinoma cells during chemotherapy
... ple, miR-449a was reported to regulate prolif- eration and chemosensitivity to cisplatin by tar- geting cyclin D1 and BCL2 in SGC7901 cells [30] and miR-125b inhibitor enhance the che- mosensitivity of ...
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Lost in translation: microRNAs mediate pathological cross-talk between motor neurons and astrocytes
... of miR-218 from dying neurons drives loss of the astrocytic glutamate transporter (EAAT2/Glt1), which contributes to excitotoxicity and exacerbates the inflammatory reaction of astrocytes surrounding the ...
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