miR-301a
Original Article miR-301a promotes cell proliferation by directly targeting TIMP2 in multiple myeloma
... of miR-301a in ...of miR-301a in MM cells. Results: MiR-301a is significantly up-regulated in MM clinical bone marrow samples and cell lines compared with normal ...that ...
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Original Article Suppression of miR-301a alleviates LPS-induced inflammatory injury in ATDC5 chondrogenic cells by targeting Sirt1
... of miR-301a ag- gravated the LPS-induced cell injury and in- creased the expression of inflammatory cyto- kines (IL-1β, IL-6, IL-8, and TNF-α), while sup- pression of miR-301a reversed these ...
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Infiltrated pre-adipocytes increase prostate cancer metastasis via modulation of the miR-301a/androgen receptor (AR)/ TGF-β1/Smad/MMP9 signals
... High fat dietary intake may increase the risk of prostate cancer (PCa). Pre-adipocytes, one of the basic components in the tumor microenvironment (TME), are capable of differentiating into adipose tissues and play key ...
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Long noncoding RNA EPB41L4A-AS2 inhibits hepatocellular carcinoma development by sponging miR-301a-5p and targeting FOXL1
... with miR-301a-5p via bioinformatics ana- lysis ...of miR-301a-5p in SMMC-7721 and QGY-7703 cells with EPB41L4A-AS2 over-expression ...of miR-301a-5p was nega- tively correlated ...
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<p>MiR-301a Promotes Cell Proliferation by Repressing PTEN in Renal Cell Carcinoma</p>
... endogenous miR-301a expression in all RCC cell lines tested was obviously higher than that in the normal human proximal tubule epithelial cell line ...of miR-301a in all kinds of RCC cells, ...
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Glycine confers neuroprotection through microRNA-301a/PTEN signaling
... of miR-130/ 301a family. miR-301a has been shown to involve in some biological and pathological processes, including cell devel- opment, cell differentiation, inflammation, apoptosis and ...
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MicroRNA-301a promotes migration and invasion by targeting TGFBR2 in human colorectal cancer
... of miR-301a and the luciferase reporter gene assay successfully identi- fied the binding site for miR-301a on the 3’-UTR of TGFBR2 ...of miR-301a in CRC cells upregulated the ...
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Advance in microRNA as a potential biomarker for early detection of pancreatic cancer
... [10]. MiR-21, for instance, is classified as an oncogene because whose over-expression is associated with the increased proliferation, invasion, and chemoresis- tance of pancreatic cancer cells to ...Like ...
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Original Article MicroRNA-301a promotes growth and migration by repressing TGFBR2 in non-small cell lung cancer
... of miR-301a mimics signifi- cantly decreased the mRNA levels of six genes (TGFBR2, SMAD4, RUNX3, PIAS3, NKRF, and FOXF2) whereas transfection with anti-miR- 301a caused significant increases ...
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MicroRNA-301a-3p promotes pancreatic cancer progression via negative regulation of SMAD4
... that miR- 301a-3p was overexpression [27] and Lu et ...between miR-301a-3p and NF-κB in which miR-301a-3p repressed NF-κB-repressing factor to elevate NF-κB activity that in turn ...
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Effects of hyperglycemia on the progression of tumor diseases
... There are conflicting views. Lee et al. [60] reported that the risk of prostate cancer was reduced in patients with diabetes. Some metabolic and hormonal factors, in- cluding blood glucose and insulin, may involve. How- ...
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Loss of has-miR-337-3p expression is associated with lymph node metastasis of human gastric cancer
... of miR-223, miR-21, miR-218, and miR-25 have been linked to gastric cancer metastasis ...elevated miR-21 expression is associated with lymph node metasta- sis of gastric cancer ...
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Investigating the mechanism of hepatocellular carcinoma progression by constructing genetic and epigenetic networks using NGS data identification and big database mining method
... (mir-148a, mir-374a and mir-494) in the MAPK and ErbB pathways cause cell proliferation, adhesions and migration and the immune cell infiltration to cancer cells during early ...and mir-590) ...
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The PTTG1-targeting miRNAs miR-329, miR-300, miR-381, and miR-655 inhibit pituitary tumor cell tumorigenesis and are involved in a p53/PTTG1 regulation feedback loop
... whether miR-329, miR-300, miR-381 and miR-655 affect cell motility in vitro, cell invasion and migration assays were performed using transwell chambers with or without ...with miR-329, ...
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Original Article A three-miRNA signature as a potential biomarker for the diagnosis of glioma
... of miR-17, miR-130a, and miR-10b were markedly increased in the plasma of gliomas compared to in healthy individuals (all ...of miR-17, miR-130a, and miR-10b was ...the ...
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A useful method of identifying of miRNAs which can down regulate Zeb 2
... To examine the effect of microRNAs to epithelial mesen- chymal transition, we performed morphological observa- tion and fluorescent staining of filamentous actin (F-actin) in transfected cells. Normal human kidney HK-2 ...
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Analysis of tissue and circulating microRNA expression during metaplastic transformation of the esophagus
... them, miR-143, miR-145, miR-194, miR-203, miR- 205, miR-215 appear to have a key role in the metaplasia and in neoplastic progression ...
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Expression of miR-15b, miR-29b, miR-219 and miR-222 microRNAs in rats with focal cerebral ischemia submitted to physical exercise
... miRNAs: miR-21, miR-34, 28a, miR-98a, miR -148b, miR-7a and miR-15b, and others with decreased expression levels: miR-105 and miR-133b (Fernandes et ...
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MiR-26a/miR-26b represses tongue squamous cell carcinoma progression by targeting PAK1
... of miR-494, functioned as an oncogenic factor in breast cancer via activating MAPK signaling pathway and remodeling cytoskeletal ...of miR-98 on growth and mobility of NSCLC cells ...of miR-26a and ...
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miR-495 inhibits proliferation, migration, and invasion and induces apoptosis via inhibiting PBX3 in melanoma cells
... of miR-495 in A375 and MeWo cells were ...that miR-495 expression was upregulated or downregulated in A375 and MeWo cells after transfection with miR-495 mimics or miR-495 inhibitors, ...
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