miR-375
A microRNA profile of saliva and the role of miR 375 in Haemaphysalis longicornis (Ixodida: Ixodidae)
... The miR-375 is one of the 20 most highly expressed miRNAs in tick saliva and cur- rently there is no study on miR-375 in ...of miR-375 in different stages (egg, unfed larva, fed ...
9
Upregulated expression of serum exosomal miR-375 and miR-1307 enhance the diagnostic power of CA125 for ovarian cancer
... Tumor biomarker are now the focus of tumor re- search, recent studies have discovered various potentials of tumor biomarker in Gynecological Oncology in addition to the diagnostic. For example, p16 INK4a pro- tein has ...
9
Original Article The involvement of miR-375 in the adriamycin resistance of pancreatic carcinoma cells
... whether miR-375 medi- ates the YAP1 expression, proliferation, apoptosis, and Adriamycin (ADM) resistance of pancreatic carcinoma ...between miR-375 and ...an miR-375 mimic ...
10
Original Article miR-375 is downregulated by promoter hypermethylation in MIN6 insulinoma cells
... from cell cultures by the miRNeasy Mini Kit and cDNA was prepared from the miScript II RT Kit (Qiagen). qRT-PCR was carried out on an ABI Prism 7300 Fast Real-time PCR System (Applied Biosystems). SYRB-Green for the tar- ...
8
<p>A Chemotherapy-Driven Increase in Mcl-1 Mediates the Effect of miR-375 on Cisplatin Resistance in Osteosarcoma Cells</p>
... of miR-375 in OS cells. The knockdown of Mcl-1 phenocopied miR-375 downregulation, and the overexpression of miR-375 rescued the effects of cisplatin-induced DNA damage mediated ...
11
<p>Circ-PRKDC Contributes to 5-Fluorouracil Resistance of Colorectal Cancer Cells by Regulating miR-375/FOXM1 Axis and Wnt/β-Catenin Pathway</p>
... circ-PRKDC, miR-375 and ...); miR-375: (F: 5 ʹ -TTTGT TCGTTCGGCTCGC-3 ʹ and R: 5 ʹ -GCTGTCAACGATA CGCTACGT-3 ʹ ); FOXM1: (F: 5 ʹ -CGTCGGCCACTGATTC TCAAA-3 ʹ and R: 5 ʹ -GGCAGGGGATCTCTTAGGTTC ...
15
miR-93/miR-106b/miR-375-CIC-CRABP1: a novel regulatory axis in prostate cancer progression
... that miR-93, miR-106b, and miR-375 promote prostate cancer progression in part by down-regulation of CIC ...of miR-93, miR-106b, and miR-375 resulted in ...
15
Original Article Decreased serum miR-375 and miR-320a levels are useful in predicting liver cancer
... that miR-375 and miR- 320a are closely related to the differen- tiation and proliferation of hepatoma ...of miR-375 and ...of miR-375 combined with miR-320a in the ...
8
<p>Circular RNA circLPAR3 Facilitates Esophageal Squamous Cell Carcinoma Progression Through Upregulating HMGB1 via Sponging miR-375/miR-433</p>
... TA-3ʹ; miR-375, F 5ʹ-AGCCGTTTGTTCGTTCGGCT-3ʹ, R 5ʹ-GTGCAGGGTCCGAGGT-3ʹ; miR-433, F 5ʹ-TCGG CAATCATGATGGGCTCCTC-3ʹ, R 5ʹ-CTCAACTGGTGT CGTGGAGTC-3ʹ; U6, F 5ʹ-GCAGGAGGTCTTCACAGA GT-3ʹ, R ...
13
Original Article miR-375 enhances palmitate-induced lipoapoptosis in insulin-secreting NIT-1 cells by repressing myotrophin (V1) protein expression
... miRNA, mir-375, in the regulation of β- cell function and the maintenance of normal pancreatic α- and β-mass ...of mir- 375 in the regulation of palmitate-induced β-cell ...ectopic ...
11
Long noncoding RNA MLK7-AS1 promotes ovarian cancer cells progression by modulating miR-375/YAP1 axis
... Total RNA was extracted from human ovarian cancer tissues and ovarian cancer cells and reversely transcribed into cDNAs by using a Reverse Transcription Kit (Toyobo, Tokyo, Japan). SYBR Green Real time PCR Master Mix ...
18
MiR-375 Has Contrasting Effects on Newcastle Disease Virus Growth Depending on the Target Gene
... with miR-375 inhibit NDV ...miR375, miR-NC, sponge-375, or sponge-NC were used to culture the DF-1 cells after rLa Sota-GFP or F48E9 was incubated for 1 ...
14
Involvement of miR 214 and miR 375 in Malignant Features of Non Small Cell Lung Cancer by Down Regulating CADM1
... of miR-214 significantly enhanced the colony formation of A549 ...addition, miR-375 slightly promoted colony for- mation, although not in a statistically significant ...
9
Hsa-miR-375 is a predictor of local control in early stage breast cancer
... Ward et al. combined in vitro data with retrospective clinical results. Hsa-miR-375 was found to be down- regulated in Tamoxifen resistant cells. Its re-expression reverses both Tamoxifen resistance and ...
13
Delivery of miR-375 and doxorubicin hydrochloride by lipid-coated hollow mesoporous silica nanoparticles to overcome multiple drug resistance in hepatocellular carcinoma
... LH/ miR-375 in HepG2/ADR cells using a confocal microscope (Figure ...LH/ miR-375 were retained in late endosomes, whereas some LH/ miR-375 entered ...h, miR-375 ...
17
Original Article Enhanced expression of miR-375 increases chemotherapy sensitivity of prostate cancer to cisplatin
... of miR-375 in prostate cancer tissues and the adjacent nor- mal tissues were determined in 10 cases of prostate ...that miR-375 lev- els were significantly down-regulated in 10 cases of ...
7
Upregulation of miR-375 level ameliorates morphine analgesic tolerance in mouse dorsal root ganglia by inhibiting the JAK2/STAT3 pathway
... 5 μL) was delivered via intraganglionic (i.g.) injection into the right L4–L5 DRGs. For i.t. injection, intraspinal punc- ture was performed with a 30-gauge syringe needle between the L5 and L6 interspace to deliver the ...
9
Original Article Epigenetic regulation of miR-375 in human colorectal cancer cells: a key role of DNA methylation
... that miR-375 is a multifunctional miRNA participating in pancreatic islet develop- ment, glucose homeostasis, mucosal immuni- ty, lung surfactant secretion and more impor- tantly, tumorigenesis ...Recently, ...
12
Potential involvement of miR-375 in the premalignant progression of oral squamous cell carcinoma mediated via transcription factor KLF5
... that miR-375 is a suppressive miRNA involved in malignant ...that miR-375 can bind directly to the 3′-UTR of KLF5, encoding an important transcription ...that miR-375 expression ...
14
Original Article Mir-375 enhances ruthenium-derived compound Rawq01 induced cell death in human ovarian cancer
... that mir-375 down-regulation is a common phe- nomenon in pancreatic cancer, hepatocellular cancer, gastric cancer, head and neck cancer and esophageal cancer [3, 14, 15, 25, ...26]. Mir- 375 ...
8