MiR-98
Targeted regulation of MiR-98 on E2F1 increases chemosensitivity of leukemia cells K562/A02
... tumors. miR-98 belongs to the let-7 family, and its overexpression can increase the sensitivity to drugs in solid cancer ...of miR-98 in leukemia is still ...of miR-98 on drug ...
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Downregulated miR-98-5p promotes PDAC proliferation and metastasis by reversely regulating MAP4K4
... 4b-c, miR-98-5p negatively regulated MAP4K4 expression at both mRNA and protein ...of miR-98-5p was proved by dual luciferase reporter ...and miR-98-5p-mimics in CFPAC-1 cells ...
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Original Article Over-expression of miR-98 in FFPE tissues might serve as a valuable source for biomarker discovery in breast cancer patients
... of miR-98 to discriminate between breast cancer patients and ...determined, miR-98 Figure 1. The miR-98 exhibited higher expression levels in breast cancer patients compared with ...
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Altered Expression of Circulating miR-377 and miR-98 in Relapsing-remitting Multiple Sclerosis
... of miR- 377 in both recurring patients and two months after relapse ...of miR-377 can be a potential therapeutic target to inhibit RRMS progression in future ...of miR-98 decreased ...
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MiR-98 modulates macrophage polarization and suppresses the effects of tumor-associated macrophages on promoting invasion and epithelial–mesenchymal transition of hepatocellular carcinoma
... that miR-98 has sup- pressive effects on several cancers, such as oral squa- mous cell carcinoma, non-small-cell lung cancer, glioma, melanoma and HCC [17, ...of miR-98 enhanced the EMT of ...
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miR-98 targets <em>ITGB3</em> to inhibit proliferation, migration, and invasion of non-small-cell lung cancer
... of miR-98 on ITGB3 expression, miR-98 target luciferase reporter assay aiming to the fragments of the 3 ′ -UTR of ITGB3 was applied (Figure ...the miR-98 mimics group com- pared ...
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<p>LncRNA HEIH Confers Cell Sorafenib Resistance in Hepatocellular Carcinoma by Regulating miR-98-5p/PI3K/AKT Pathway</p>
... example, miR-137 sensitized sorafenib-resistant HCC cells to sorafenib via inhibiting ANT2 ...22 MiR-21 contributed to sorafenib resistance in HCC cells through sup- pressing autophagy by the Akt/PTEN ...to ...
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Original Article miR-98 suppresses tumor cell growth and metastasis by targeting IGF1R in oral squamous cell carcinoma
... progression. miR-98 was an tumor sup- pressive miRNA and decreased in different human cancers [9, ...of miR-98 could contribute to the initiation and progression of ...that ...
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MicroRNA miR-98 inhibits tumor angiogenesis and invasion by targeting activin receptor-like kinase-4 and matrix metalloproteinase-11
... microRNA miR-98 in regulating tumor growth, invasion, and angiogenesis using a highly aggressive breast cancer model in vitro and in ...of miR-98 inhibited breast cancer cell proliferation, ...
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miR-98 functions as a tumor suppressor in salivary adenoid cystic carcinomas
... quantify miR-98 expression in SACC cell lines as well as in the primary tumors and adjacent ...of miR-98 on N-RAS expression was examined by Western blotting and immunofluorescence ...of ...
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microRNA-98 mediated microvascular hyperpermeability during burn shock phase via inhibiting FIH-1
... these, miR-98 was found expressed to the greatest extent during hypoxia in squamous cell carcinoma ...upregulated miR-98 in rat models of burn and burn serum- stimulated rat vascular ...
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MicroRNA-98 acts as a tumor suppressor in hepatocellular carcinoma via targeting SALL4
... the miR-98 expression and the clinicopathological features of ...high miR-98 expression group and low miR-98 expression group, according to the mean value of the ...
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MicroRNA-98 inhibits the cell proliferation of human hypertrophic scar fibroblasts via targeting Col1A1
... MicroRNA 98 is reported to be related with many ...between miR-98 and IGF-1 [19]. MiR-98 has been demonstrated to mediate the antihypertrophic effect of thioredoxin (Trx1) ...
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Aberrant plasma levels of circulating miR-16, miR-107, miR- 130a and miR-146a are associated with lymph node metastasis and receptor status of breast cancer patients
... of miR-107 and its down-regulation in estrogen treated MCF-7 cells ...of miR-107. Moreover, we found that inhibition of miR-107 may stimulate migration of MCF-7 cells and invasion of MCF-7 and ...
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MiR-21 and MiR-155 promote non-small cell lung cancer progression by downregulating SOCS1 SOCS6 , and PTEN
... of miR-21, miR-155 and miR-214 in different stages of NSCLC, we divided 80 paired human normal and NSCLC samples into three groups according to the disease ...of miR-21, miR-155 and ...
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The aberrant expression of microRNAs and correlations with T cell subsets in patients with immune thrombocytopenia
... of miR-146a on Th differentiation was evaluated after using ...of miR-146a, miR-326 or miR-142-3p in ITP patients was lower than that of ...of miR-142-3p and miR-146a were ...
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Interactions of miR 323/miR 326/miR 329 and miR 130a/miR 155/miR 210 as prognostic indicators for clinical outcome of glioblastoma patients
... on miR-130a, with ...of miR-326 and ...low miR-130a was ...low miR-323 and miR-130a was 30.9months, and that with both low miR-323 and high miR-130a was ...
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Analysis of tissue and circulating microRNA expression during metaplastic transformation of the esophagus
... these, miR-143, miR-145, miR-194, miR-203, miR-205, miR-215 appear to have a key role in metaplasia and neoplastic ...that miR-143, miR-145, miR-194 and ...
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A useful method of identifying of miRNAs which can down regulate Zeb 2
... To examine the effect of microRNAs to epithelial mesen- chymal transition, we performed morphological observa- tion and fluorescent staining of filamentous actin (F-actin) in transfected cells. Normal human kidney HK-2 ...
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Multiple microRNAs regulate human FOXP2 gene expression by targeting sequences in its 3' untranslated region
... let-7a, miR-9, and miR-129-5p in the human FOXP2 3 ′ ...let-7a, miR-9, and miR-129-5p in the FOXP2 3 ′ UTR abolished the repressive effects of these miRNAs in luciferase reporter ...
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