Mitochondrial ATP synthase (ATPase)
The ε-Subunit of Mitochondrial ATP Synthase Is Required for Normal Spindle Orientation During the Drosophila Embryonic Divisions
... of mitochondrial ATP synthase is markedly reduced in sun mutants: Mitochondrial ATP synthase both synthesizes and breaks down ...of mitochondrial ATP ...
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The potential role of mitochondrial ATP synthase inhibitory factor 1 (IF1) in coronary heart disease: a literature review
... cytosolic ATP and to the improvement of time-averaged energy state of the heart during subsequent episodes of prolonged ischemia ...that mitochondrial ATP synthase inhibitory factor 1 (IF1) is ...
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Mitochondrial ATP synthase disorders: Molecular mechanisms and the quest for curative therapeutic approaches
... of ATP and its release from the enzyme. The biogenesis of the mitochondrial ATP synthase is a sophisti- cated process, which depends on the coordinated expression of the nuclear and ...
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The peripheral stalk of the mitochondrial ATP synthase
... The mitochondrial peripheral stalk is an assembly of single copies of the oligomycin sensitivity conferral protein (the OSCP) and subunits b, d and F 6 ...the mitochondrial and bacterial ...of ATP ...
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The Oligomycin-Sensitivity Conferring Protein of Mitochondrial ATP Synthase: Emerging New Roles in Mitochondrial Pathophysiology
... for ATP synthesis, but also modulates the enzyme complex and is the target of inhibitors and interactors, including ...affects ATP synthase activity and, most importantly, decreases the threshold ...
24
Mutations in the mitochondrial ATP synthase gamma subunit suppress a slow-growth phenotype of yme1 yeast lacking mitochondrial DNA.
... Previous work has demonstrated that opl yeast strains rapidly become inviable when mtDNA is lost (KOVA- COVA et al. As shown in Figure 1, the loss of mtDNA as a r[r] ...
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Subunit Asa1 spans all the peripheral stalk of the mitochondrial ATP synthase of the chlorophycean alga Polytomella sp.
... Abstract: Mitochondrial F1FO-ATP synthase of chlorophycean algae is isolated as a dimer. Besides the eight orthodox subunits (alpha, beta, gamma, delta, epsilon, OSCP, a and c), the enzyme contains ...
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A functional mitochondrial ATP synthase proteolipid gene produced by recombination of parental genes in a petunia somatic hybrid.
... All transcript termini were located by electrophoresing the protected fragments next to sequence ladders or pBR322 size markers (data not shown) and are indicated i[r] ...
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Investigation Of Mutations In Nuclear Genes That Affect The Atp Synthase
... The ATP synthase is a multimeric enzyme that consists of nineteen different ...the ATP synthase is divided into three separate ...the mitochondrial F 1 - ATPase and therefore more ...
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A Nuclear restorer-of-fertility Mutation Disrupts Accumulation of Mitochondrial ATP Synthase Subunit α in Developing Pollen of S Male-Sterile Maize
... Grivell, L. A., M. Artal-Sanz, G. Hakkaart, L. de Jong, L. G. J. Shoubridge, E. A., 2001 Nuclear genetic defects of oxidative phos- Nijtmans et al., 1999 Mitochondrial assembly in yeast. FEBS phorylation. Hum. ...
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ATP Synthase Is Responsible for Maintaining Mitochondrial Membrane Potential in Bloodstream Form Trypanosoma brucei
... the ATP synthase ␣ and  subunits in order to study the function of the mitochondrial ATP synthase in the bloodstream stages of ...the ATP syn- thase  subunit was mediated by ...
9
Knockdown of F1 epsilon subunit decreases mitochondrial content of ATP synthase and leads to accumulation of subunit c
... The cell lines exerted normal viability under standard cultivation conditions. There was no signi ficant difference in cell growth rate between the silenced and control cell lines. The cell lines were analyzed for the ...
6
The essential oils component <em>p</em>-cymene induces proton leak through Fo-ATP synthase and uncoupling of mitochondrial respiration
... of ATP, their role in controlling pathways of intracellular Ca 2+ homeostasis, 18 apoptotic and necrotic cell death, 19 and the critical role of mitochondrial impairment in a vast number of disorders, 20,21 ...
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Suppression of a Nuclear aep2 Mutation in Saccharomyces cerevisiae by a Base Substitution in the 5′-Untranslated Region of the Mitochondrial oli1 Gene Encoding Subunit 9 of ATP Synthase
... of mitochondrial oli1 mRNA, encoding subunit 9 of mitochondrial ATP ...a mitochondrial suppressor: these lost the ability to suppress aep2-ts1 when their mitochondrial genome was ...
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ATP Synthase Diseases of Mitochondrial Genetic Origin
... in ATP synthase ...of ATP, defects in ATP synthase may have multiple secondary effects, such as increased production of ROS and changes in upstream metabolic processes (Korshunov et ...
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On the structural possibility of pore-forming mitochondrial FoF1 ATP synthase
... 1 ATP synthases in the last year [24 –26,72] , a high resolution structure that includes water, lipids and ligands does not seem to be around the ...1 ATP synthase in mito- chondria will always leave ...
6
Persistence of the mitochondrial permeability transition in the absence of subunit c of human ATP synthase.
... the mitochondrial genome (25); all the other subunits of the human complex are the products of single nuclear genes, except for subunit c which is encoded by three genes, ATP5G1, ATP5G2 and ATP5G3 (31, 32) ...
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New insights into S. cerevisiae F-ATP synthase and its role in the mitochondrial permeability transition
... F-ATP synthase 30 | P a g . multimicronucleatum. They observed that F-ATP synthase complexes formed a paired row around the outer curve of helical tubules 70 ...F-ATP synthase is ...
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Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology
... SUMMARY We determined the structure of a complete, dimeric F 1 F o -ATP synthase from yeast Yarrowia lipolytica mitochondria by a combination of cryo-EM and X-ray crystallography. The final structure ...
13
Molecular studies on the energy-transducing ATP synthase
... Most of the fusion protein was soluble, but only a small proportion bound to the glutathione agarose beads following exposure to the supernatant, and the majority remained in the u[r] ...
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