Mitochondrial Bioenergetics
Cycling Exercise Training Enhances Mitochondrial Bioenergetics of Platelets in Patients with Peripheral Arterial Disease: A Randomized Controlled Trial
... (PAD). Mitochondrial functionalities in platelets involve the cellular bioenergetics and ...platelet mitochondrial bioenergetics in PAD ...platelet mitochondrial bioenergetics ...
26
Mutant TDP-43 does not impair mitochondrial bioenergetics in vitro and in vivo
... that mitochondrial bioenergetics is essentially un- affected by mutant TDP-43, we conclude that the mitochondrial dynamics abnormalities are not the result of intrinsic mitochondrial ...
15
Long noncoding RNA Tug1 regulates mitochondrial bioenergetics in diabetic nephropathy
... of mitochondrial function in ...in mitochondrial bioenergetics in the podocytes of diabetic ...modulates mitochondrial bioenergetics in podocytes in the diabetic ...
15
Brain mitochondrial bioenergetics change with rapid and prolonged shifts in aggression in the honey bee, Apis mellifera
... brain mitochondrial function in the current study, we found that stable increases in aggression that typically accompany ageing are associated with increased whole- brain mitochondrial respiration, matching ...
10
<p>Relationships between expression of BCS1L, mitochondrial bioenergetics, and fatigue among patients with prostate cancer</p>
... With limited available options to manage CRF, strate- gies are needed to identify effective interventions. To guide the development of effective therapies for the management of CRF, identi fi cation of pathophysiological ...
15
<p>OGDH promotes the progression of gastric cancer by regulating mitochondrial bioenergetics and Wnt/β-catenin signal pathway</p>
... cycle to better utilization of available fuels for the high bioernergetic and biosynthetic requirements of cancer cells. OGDHC activity is essential for the forward TCA cycle and the ETC chain. Vatrient et al reported ...
12
Effect of antipsychotics on mitochondrial bioenergetics of rat ovarian theca cells
... on mitochondrial bioenergetics of rat ovarian theca cells as a possible mechanism of reproductive ...TICs bioenergetics (ATP content, mitochondrial complexes I and III activities, oxygen ...
22
Soluble Fms-like tyrosine kinase-1 alters cellular metabolism and mitochondrial bioenergetics in preeclampsia
... metabolism, mitochondrial bioenergetics and mitochondrial dysfunction, linked to oxidative stress in ECs and first trimester EVT (HTR-8/SVneo ...
13
Effects of hypoxia–cadmium interactions on rainbow trout (Oncorhynchus mykiss) mitochondrial bioenergetics: attenuation of hypoxia induced proton leak by low doses of cadmium
... coupling. Mitochondrial complex I activity was inhibited by hypoxia/reoxygenation, hence confirming the impairment of at least one component of the electron transport chain (ETC) in rainbow trout ...on ...
10
Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons
... the mitochondrial bioenergetics profile in sen- sory neurons derived from DRG of 3 – 5 month STZ- diabetic mice, the oxygen consumption rate (OCR) was measured in neurons cultured for 24 h using the ...
15
Mitochondrial Bioenergetics and Neuromuscular Weakness of Acute Organophosphate Poisoning.
... Complex IV (cytochrome c oxidase), the terminal enzyme of the electron transport chain, is a homo-dimer and each monomer is composed of 13 subunits of molecular weight of ~200 kDa (96). The complex receives two electrons ...
155
Skeletal muscle mitochondrial bioenergetics and associations with myostatin genotypes in the Thoroughbred horse
... However, protein levels, as measured by immunoblotting were not different among the genotypes suggesting that the transcript level is decreased without a coinciding decrease in protein level. Although seemingly unusual, ...
23
Skeletal muscle dysfunction is associated with derangements in mitochondrial bioenergetics (but not UCP3) in a rodent model of sepsis
... complex activity and lower oxygen consumption in tissues and cells taken from septic. 537[r] ...
42
Relationships between mitochondrial content and bioenergetics with obesity, body composition and fat distribution in healthy older adults
... muscle mitochondrial bio- energetics in middle aged adults, relatively little is known about the relationship of adiposity on mitochondrial func- tion in older adults, a population that has been shown to ...
11
Circadian control of DRP1 activity regulates mitochondrial dynamics and bioenergetics
... in mitochondrial bioenergetics, mitochondrial fission was abolished by selective inhibition of DRP1 using the inhibitor P110 (1 μM) or inhibition of complex I using the inhibitor Mdivi-1 (50 ...
53
Bioenergetics in fibroblasts of patients with Huntington disease are associated with age at onset
... lower mitochondrial respiration indices, including lower maximal respiration, spare capacity, and respiration de- pendent on complex II activity in an absolute sense, as well as relative to their basal respiration ...
13
Transcriptomic-metabolomic reprogramming in EGFR-mutant NSCLC early adaptive drug escape linking TGFβ2-bioenergetics- mitochondrial priming
... prosurvival mitochondrial marker BCL-xL as an important and necessary co-target in addition to BCL-2 itself, to achieve optimal therapeutic efficacy to eradicate the emergence of adaptive EGFR- TKI ...
15
Targeting the mitochondrial inner membrane to improve bioenergetics in the diseased heart
... The direct consequence of IR-induced structural alterations of the MRCs is inefficient electron transfer. The latter results in secondary electron leak leading to increased ROS generation [166-168]. Furthermore, IRI is ...
125
Pinin protects astrocytes from cell death after acute ischemic stroke via maintenance of mitochondrial anti-apoptotic and bioenergetics functions
... declined mitochondrial dehydrogenase activity and the increase in LDH re- leased into the medium indicative of mitochondrial malfunction; alongside the reduction in ATP levels amply ascertained that ...
14
Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients
... parameters: mitochondrial membrane potential, cellular ATP content, cell respiration, and ...of mitochondrial membrane potential, was significantly higher in all disease groups relative to controls (sALS ...
12