Mitochondrial homeostasis
Kruppel like factor 4 is critical for transcriptional control of cardiac mitochondrial homeostasis
... governs mitochondrial biogenesis, metabolic function, dynamics, and autophagic ...in mitochondrial shape, size, ultrastructure, and ...impaired mitochondrial biogenesis, and altered ...
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Bax inhibitor 1 preserves mitochondrial homeostasis in acute kidney injury through promoting mitochondrial retention of PHB2
... intrinsic mitochondrial apoptosis cascade ...governing mitochondrial protection led to the identification of a protein with apparently anti-mitochondrial apoptosis activity which hence was termed Bax ...
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Ataxia telangiectasia mutated kinase regulates ribonucleotide reductase and mitochondrial homeostasis
... to mitochondrial DNA (mtDNA) depletion under normal growth ...high mitochondrial transcription factor A (mtTFA)/mtDNA ratios, and increased resistance to inhibitors of mitochondrial respiration and ...
13
SIRT3 Activation by Dihydromyricetin Suppresses Chondrocytes Degeneration via Maintaining Mitochondrial Homeostasis
... on mitochondrial dysfunction in ...(LV-Ctrl). Mitochondrial membrane potential is a indicator for mitochondrial ...p53 mitochondrial translocation is used for detecting mitochondrial ...
10
PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis
... compromise mitochondrial function and fusion/fission dynamics in AECIIs of WT ...in mitochondrial homeostasis of AECIIs, we analyzed intact primary AECIIs isolated from young (3 months) and old ...
19
The mitochondrial citrate transporter, CIC, is essential for mitochondrial homeostasis.
... inner mitochondrial membrane of the tricarboxylate citrate plus a proton for the dicarboxylate ...and mitochondrial membrane potential ...of mitochondrial activity and ...G. Mitochondrial (m) ...
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Promotion of mitochondrial fusion protects against developmental PBDE-47 neurotoxicity by restoring mitochondrial homeostasis and suppressing excessive apoptosis
... disrupted mitochondrial dynamics by inhibiting mitochondrial fusion and fission simultaneously, accompanied by mitochondrial fragmentation, membrane potential dissipation, ATP loss, and apoptosis ...
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Disruption of mitochondrial homeostasis with artemisinin unravels anti-angiogenesis effects via auto-paracrine mechanisms
... inhibited tumor growth (Figure 6B). Tumor volumes decreased significantly after intravenous (i.v.) injections of ART/NVB for 14 days, relative to those in mice administered the vehicle control (Figure 6C). Low-dose ...
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ATG5 is essential for ATG8 dependent autophagy and mitochondrial homeostasis in Leishmania major
... its homeostasis is vital and autophagy is thought to have some role in this ...of mitochondrial function being compromised in the absence of a functional autophagic pathway [24,25] and mitochondria ...
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ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major
... is mitochondrial (Gibellini, F & Smith ...phospholipid homeostasis in the mitochondrion would be disrupted and mitochondrial function thus ...as mitochondrial markers and mC-ATG5 showed ...
14
<p>Ginaton improves neurological function in ischemic stroke rats via inducing autophagy and maintaining mitochondrial homeostasis</p>
... Studies have suggested that Parkin, a ubiquitin ligase that mediates mitophagy, DRP1 and OPA1, the modulators pro- moting mitochondrial fi ssion and fusion, are all critical mole- cules to maintain the integrity of ...
10
N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting
... the mitochondrial marker Tom20 ...that mitochondrial targeting of N-Gsdma3 is not a cell type-specific ...confirm mitochondrial targeting of N-Gsdma3, we performed mitochondria/cytosol fractionations ...
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Radiation-induced heart disease: a review of classification, mechanism and prevention
... maintain mitochondrial homeostasis, improve energy metabolism of myocardial cells, and alleviate the reduction of cardiac function and cardiac structural changes ...
11
Regulation of mitochondrial dynamics in adipose tissue
... In Chapter 2, higher adiposity was shown to increase the expression of mitochondrial fission (Drp1 and Fis1) and fusion genes (Mfn2 and Opa1) in overweight and obese AbSc AT (Figures 2.4 and 2.5). Obesity is known ...
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Apocynin prevents mitochondrial burdens, microglial activation, and pro-apoptosis induced by a toxic dose of methamphetamine in the striatum of mice via inhibition of p47phox activation by ERK
... p47; mitochondrial translocation of cleaved cleaved form of protein kinase C delta type (PKCδ); mitochondrial membrane potential; intramitochondrial Ca 2+ level; ROS formation; phosphorylations of ERK, p38 ...
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A γ-Secretase Independent Role for Presenilin in Calcium Homeostasis Impacts Mitochondrial Function and Morphology in Caenorhabditis elegans
... to mitochondrial morphology defects as observed in SEL-12-deficient ...impacting mitochondrial function is independent of g-secretase ...the mitochondrial defects that we observe in SEL-12-deficient ...
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Manganese Homeostasis in Group A Streptococcus Is Critical for Resistance to Oxidative Stress and Virulence
... GAS is an obligate human pathogen responsible for a wide variety of diseases ranging from mild infections such as impetigo and pharyngitis to life-threatening invasive diseases such as strep- tococcal toxic shock ...
10
The conceptualisation of health and disease in veterinary medicine
... Homeopathic health definitions were stated to be 'holis- tic' and were mainly based on the idea that health is depending on homeostasis. However, as health definition of conventional veterinary textbooks also ...
6
Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis
... abnormal mitochondrial morphology, deteriorated mitochondrial functions, abnor- mal photoreceptor inner and outer segments, and reduced electroretinography (ERG) ...and homeostasis and provide new ...
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Impact of milk consumption on cardiometabolic risk in postmenopausal women with abdominal obesity
... Data from randomized clinical studies meta-analysed in [49] indicated that intake of high fat dairy, not low fat dairy, increases plasma glucose concentrations. This appar- ent hyperglycemic effect of high fat dairy was ...
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