Mitochondrial matrix
The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in Hominidae
... outer mitochondrial membrane was removed by hypo- osmotic swelling as indicated by the disappearance of the porin ...the matrix protein Mge1 were monitored in parallel samples using autoradiography for ...
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The PB2 Subunit of the Influenza A Virus RNA Polymerase Is Imported into the Mitochondrial Matrix
... the mitochondrial matrix affect MAVS function and innate immune responses? PB2 could inter- fere with MAVS function by affecting the MMP, in a way similar to that proposed for influenza A virus protein ...
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Original Article Cardiac Mitochondrial Membrane Stability after Deep Hypothermia using a Xenon Clathrate Cryostasis Protocol – an Electron Microscopy Study
... the mitochondrial matrix in a cardiomyocyte after incubation at high-pressure nitrogen-oxygen gas mixture and cooling in liquid nitrogen (scale bar — ...
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Mitochondrial Protein in the Nucleus
... the mitochondrial matrix in response to oxidative stress and triggers mitochondrial permeability transition and necrosis ...the mitochondrial sirtuin Sirt3 ...
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Procaspase-9 is attached to the mitochondrial outer membrane in the early stages of apoptosis
... the mitochondrial outer membrane (the TOM complex, translocase of the outer membrane) [24], which can function by itself for a small subset of outer membrane proteins or with other protein import complexes in the ...
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Evaluation of functioning of mitochondrial electron transport chain with NADH and FAD autofluorescence
... of mitochondrial electron transport chain function in isolated mitochondria of smooth muscle cells of rats from uterus using fluorescence of NADH and FAD ...of mitochondrial electron transport ...in ...
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Clinical Reasoning: A 45-year-old man with weakness and myalgia after orthopedic surgery
... DISCUSSION CPT2 deficiency is a disorder of long- chain fatty acid oxidation and is one of the most common metabolic myopathies. During times of increased metabolic demands, energy production in muscle cells transitions ...
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Mapa, Koyeli (2009): Conformational Dynamics of the Mitochondrial TIM23 Preprotein Translocase. Dissertation, LMU München: Medizinische Fakultät
... the matrix, Tim21 leaves the sorting module and the import motor joins the rest to make the matrix translocation ...the mitochondrial matrix (Popov-Celeketic et ...of matrix targeted ...
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Chlamydomonas Immunophilins and Parvulins: Survey and Critical Assessment of Gene Models
... or mitochondrial matrix, the N-terminal sequence of CYN51 has typical features of a dual targeting sequence, suggesting that the protein could end up in the thylakoid ...
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The mitochondrial calcium uniporter regulator 1 (MCUR1) matrix domain is a self-associated multimer sensitive to divalent cations
... Part of the reason MCUR1 is believed to act as a scaffolding factor stems from its ability to interact with multiple proteins in the heteromeric MCU complex assembly. Coimmunoprecipitation studies have identified MCU and ...
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“Mitochondrial remodeling” in coronary heart disease
... and mitochondrial energy production in cardiac ...of mitochondrial matrix calcium through the MCU, which is regulated by the MiCU1, activates matrix calcium-dependent dehydrogenases, and then ...
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Mitochondrial disorders: aetiologies, models systems, and candidate therapies
... the mitochondrial matrix, in a process involving membrane fusion [62]; inclusion of a mitochondri- al targeting signal (MTS) peptide with MITO-Porter en- hanced mitochondrial delivery ...the ...
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A role for taurine in mitochondrial function
... with mitochondrial dysfunction as unifying hypothesis ...presented mitochondrial matrix-buffering hypoth- esis, the association from hyperglycemia and lipid accu- mulation to mitochondrial ...
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Herpes Simplex Virus UL12.5 Targets Mitochondria through a Mitochondrial Localization Sequence Proximal to the N Terminus
... predominantly mitochondrial and acts to trigger degradation of the mitochondrial genome early during ...that mitochondrial localization of ...typical mitochondrial matrix localization ...
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The Mitochondrial Calcium Uniporter Is Autoregulated by Cation Binding to the β-Grasp-Like Matrix Domain
... swelling and treating the resulting mitoplasts with proteinase K (Baughman et al., 2011). Proteins such as the oxidase assembly 1 that are exposed to the IMS are digested by proteinase K, whereas cytochrome oxidase II, ...
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Global proteome of LonP1 mouse embryonal fibroblasts reveals impact on respiratory chain, but no interdependence between Eral1 and mitoribosomes
... main mitochondrial protease in these cells, there was no strong bias towards protein accumulations in the ...of mitochondrial biogenesis such as Ppargc1a, Nrf1, Nrf2, Tfam [49] or components of the ...
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Sex-associated differences in mitochondrial function in human peripheral blood mononuclear cells (PBMCs) and brain
... better mitochondrial respiration in females in reproductive ...the mitochondrial electron transport chain, including CI, CIV, and the F1 subunit of ATP syn- thase, which is consistent with our detected ...
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Inorganic Polyphosphates Regulate Hexokinase Activity and Reactive Oxygen Species Generation in Mitochondria of Rhipicephalus (Boophilus) microplus Embryo
... the mitochondrial fraction were activated during cellularization and embryo segmentation (Figure 5), while only CAT ac- tivity remained high after this phase of ...croplus, mitochondrial CAT activity was ...
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Mitochondrial Heat Shock Protein Machinery Hsp70/Hsp40 Is Indispensable for Proper Mitochondrial DNA Maintenance and Replication
... ABSTRACT Mitochondrial chaperones have multiple functions that are essential for proper functioning of ...of mitochondrial heat shock proteins 70 and 40 (mtHsp70/mtHsp40) and the ATP exchange factor ...The ...
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Blocking mitochondrial calcium release in Schwann cells prevents demyelinating neuropathies
... SC mitochondrial anom- alies and improve the phenotype of diabetic ...(A) Mitochondrial calcium, (B) cytoplasmic calcium, (C) mitochondrial pH, and (D) motility in mSCs of diabetic mice (db/db) in ...
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