Mitochondrial Proteins
Apolipoprotein E4 (1–272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells
... The proteins in the silver-stained bands were reduced with 10 mM dithiothreitol at room temperature for 2 h and alkylated with 40 mM iodoacetamide in the dark at room temperature for 30 ...
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Proteomic analysis of the postsynaptic density implicates synaptic function and energy pathways in bipolar disorder
... altered mitochondrial function at the level of the synapse that has an impact locally on protein translation and endocytosis, and so on altered synaptic ...of mitochondrial-traf fi cking proteins ...
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Mitochondrial impairment in the five-sixth nephrectomy model of chronic renal failure: proteomic approach
... Bcl-2 proteins. Two members of this family, BH3-only proteins Beclin 1 and BNIP3, were up-regulated in the PNx kidneys (Figure ...promotes mitochondrial autophagy and thus enhances kidney adaptation ...
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Renal manifestations of genetic mitochondrial disease
... the mitochondrial and the nuclear genomes have been identified in individuals with mitochondrial ...with mitochondrial disease have a negative impact on this ...function. Mitochondrial DNA ...
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Terziyska, Nadia (2008): Biogenesis of proteins of the mitochondrial intermembrane space: Identification and characterization of Mia40 in Saccharomyces cerevisiae. Dissertation, LMU München: Fakultät für Biologie
... of mitochondrial precursors is a challenging task as the organelle is bounded by two membranes of distinct lipid and protein ...many proteins regulating the mitochondrial morphology and mediating ...
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Mitochondrial biogenesis is required for the anchorage- independent survival and propagation of stem-like cancer cells
... >60 mitochondrial proteins are up-regulated in mammospheres derived from breast cancer cell lines (MCF7 and T47D), relative to cells grown in ...targeting mitochondrial ribosomes as a known ‘side ...
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Russo, Gianluca Luigi (2019): Unraveling and overcoming hurdles in direct neuronal reprogramming. Dissertation, LMU München: Graduate School of Systemic Neurosciences (GSN)
... neuronal mitochondrial protein expression during a time-course of astrocytes undergoing neuronal ...neuron-specific mitochondrial proteins indeed appear in reprogrammed neurons, but are induced late ...
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Sawyeria marylandensis (Heterolobosea) Has a Hydrogenosome with Novel Metabolic Properties
... Sawyeria marylandensis is an amoeba from anaerobic sedi- ments that belongs to the class Heterolobosea (24, 39, 48). Small subunit rRNA phylogenies (SSU rRNA) show Sawyeria branching in a robust clade with the two other ...
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Oxidative photoreceptor cell damage in autoimmune uveitis
... and mitochondrial proteins are the prime target for inactivation, further implicating photoreceptor mito- chondria as initiators of the proinflammatory response in early EAU ...photoreceptor ...
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Schreiner, Bernadette (2013): Role of the AAA protease Yme1 in folding of proteins in the mitochondrial intermembrane space. Dissertation, LMU München: Fakultät für Biologie
... of mitochondrial proteins regulate the morphological dynamics of the organelle (Shaw and Nunnari, ...the mitochondrial intermembrane space (Youle and van der Bliek, ...
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Suppression of a Defect in Mitochondrial Protein Import Identifies Cytosolic Proteins Required for Viability of Yeast Cells Lacking Mitochondrial DNA
... of proteins, the vast Yamamoto et ...of mitochondrial proteins are synthesized on act as a molecular motor to ensure unidirectional move- cytosolic ribosomes and imported post-translationally ment of ...
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Acute exercise alters skeletal muscle mitochondrial respiration and H 2emission in response to hyperinsulinemic-euglycemic clamp in middle-aged obese men
... with obesity could therefore be interpreted as the early signs of impaired metabolic flexibility which is observed in type-2 diabetes [62]. An alternative explanation is that the aforemen- tioned studies co-infused amino ...
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Synthesis and evaluation of frentizole based indolyl thiourea analogues as MAO/ABAD inhibitors for Alzheimer’s disease treatment
... Several mitochondrial proteins have been shown to interact directly with Aβ, possibly influencing mitochondrial ...and mitochondrial and synaptic ...Aβ-induced mitochondrial and ...
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SIRT3 and SIRT4 are mitochondrial tumor suppressor proteins that connect mitochondrial metabolism and carcinogenesis
... specific mitochondrial proteins ...acetylated proteins in the mitochondria, which contain reversible acetyl-lysines associated with energy homeostasis ...primary mitochondrial deacetylase, and ...
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Mitochondrial ATPase : biochemical and molecular genetic analysis
... the mitochondrial genome is a very expensive process in biochemical ...f mitochondrial proteins, but also for all the enzymes required for maintenance and replication o f mitochondrial DNA, ...
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Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins
... and mitochondrial inner membrane (IM)—that surround two distinct aqueous compartments: the intermembrane space (IMS) and the mitochondrial matrix [7, 9, ...of proteins. The best-characterized ...
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Mitochondrial Histone-Like DNA-Binding Proteins Are Essential for Normal Cell Growth and Mitochondrial Function in Crithidia fasciculata
... nucleus-encoded mitochondrial proteins suggests a possible direct effect of the loss of the KAP2 and KAP3 proteins on maxicircle gene ...KAP3 proteins were isolated initially based on chemical ...
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Baicalein antagonizes rotenone-induced apoptosis in dopaminergic SH-SY5Y cells related to Parkinsonism
... SH-SY5Y cells were pretreated with different concentra- tions of baicalein for 1 hour and then co-treated with rote- none (20 μ M) for another 6 hours in serum-free medium. According to the protocols described in our ...
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Unbiased metabolomic investigation of Alzheimer's disease brain points to dysregulation of mitochondrial aspartate metabolism
... in mitochondrial aspartate metabolism in the AD brain, which correlated with dementia and AD ...by mitochondrial aspartate metabolism in the etiology and progression of the cognitive impairment and ...
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Divergence of Erv1-Associated Mitochondrial Import and Export Pathways in Trypanosomes and Anaerobic Protists
... analyses of Erv1 function in the African sleeping sickness parasite T. brucei and (ii) a new in silico analysis aimed at clarifying the involvement of Erv1 in cytosolic Fe-S cluster assembly within evo- lutionarily ...
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