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MMC, Mitomycin C

Compare the Safety and Efficacy of Sub-conjunctival
application of Sponges Soaked in Mitomycin-C (MMC:0.02%) to that of Direct Injection of Mitomycin-C (MMC:0.02%) into the Sub-conjunctival Space in Trabeculectomy or
Phacotrabeculectomy: A Randomized Co

Compare the Safety and Efficacy of Sub-conjunctival application of Sponges Soaked in Mitomycin-C (MMC:0.02%) to that of Direct Injection of Mitomycin-C (MMC:0.02%) into the Sub-conjunctival Space in Trabeculectomy or Phacotrabeculectomy: A Randomized Controlled Trial

... Glaucoma is an ocular condition with multi-factorial etiology. The condition is most often bilateral. Progressive optic nerve damage resulting in blindness is the hallmark of untreated glaucoma. Intraocular pressure ...

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Methods for direct determination of mitomycin C in aqueous solutions and in urine

Methods for direct determination of mitomycin C in aqueous solutions and in urine

... drug mitomycin C (MMC) alone and in mixtures with 5-fluorouracil and cisplatin, both of which are used in combined chemotherapy with ...of MMC reduction (-0.35 V vs. SCE), reduced MMC ...

7

Ocular surface disease in posttrabeculectomy/mitomycin C patients

Ocular surface disease in posttrabeculectomy/mitomycin C patients

... Results: Of the 15 eyes from 12 patients, 14 were treated with MMC and one with 5-fluorouracil. Mean age was 69.3±10.6 years and two-thirds were male. The median interval before onset of dry eye symptoms after ...

5

A review of the efficacy of mitomycin C in glaucoma filtration surgery

A review of the efficacy of mitomycin C in glaucoma filtration surgery

... of MMC, and they recommended that lower doses of MMC or placing MMC in the sub-Tenon’s space without scleral dissection could potentially avoid the complication of scleral ...with MMC, its use ...

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Collagen matrix vs mitomycin-C in trabeculectomy and combined phacoemulsification and trabeculectomy: a randomized controlled trial

Collagen matrix vs mitomycin-C in trabeculectomy and combined phacoemulsification and trabeculectomy: a randomized controlled trial

... adjunctive MMC are similar to those observed with adjunctive use of CM with respect to Kaplan-Meier complete success rates and mean IOP; however, there was a significantly lower incidence of sustained hypotony in ...

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Pulmonary toxicity after intraperitoneal mitomycin C: a case report of a rare complication of HIPEC

Pulmonary toxicity after intraperitoneal mitomycin C: a case report of a rare complication of HIPEC

... for MMC-related toxicity ...peritoneal MMC is neutropenia, for which female sex and MMC dose per body surface area have been implicated as risk factors ...

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Intravesical Treatment with Vorinostat Can Prevent Tumor Progression in MNU Induced Bladder Cancer

Intravesical Treatment with Vorinostat Can Prevent Tumor Progression in MNU Induced Bladder Cancer

... combining mitomycin c (MMC), Cis- platin (DDP) and Adriamycin (ADM) were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bro- mide (MTT) ...

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The histopathological effects of intracavernosal mitomycin C injection in a rat Peyronie's disease model

The histopathological effects of intracavernosal mitomycin C injection in a rat Peyronie's disease model

... When compared with group 3 (sham group), previously described semiquantitative scores evaluating fibrosis were higher in both group 1 and group 2, and this finding was statistically significant (Table 1) (Fig. ...

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Consequences of inadvertent intravitreal Mitomycin C injection

Consequences of inadvertent intravitreal Mitomycin C injection

... intravitreal MMC injection. MMC applica- tion in the ophthalmology have been evaluated mostly in the field of ocular surface and orbital ...of MMC. One year follow up also showed toxic effects of ...

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Collaborative study of thresholds for mutagens: proposal of a typical protocol for detection of hormetic responses in cytotoxicity tests

Collaborative study of thresholds for mutagens: proposal of a typical protocol for detection of hormetic responses in cytotoxicity tests

... with mitomycin C (MMC) or ethyl methanesulfonate (EMS) at various dose levels and optical density was measured after addition of a reagent to detect cellular ...with MMC or EMS were generally ...

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AS-OCT Guided Treatment Of Diffuse Conjunctival Squamous Cell Carcinoma With Resection, Amniotic Membrane Graft And Topical Mitomycin C

<p>AS-OCT Guided Treatment Of Diffuse Conjunctival Squamous Cell Carcinoma With Resection, Amniotic Membrane Graft And Topical Mitomycin C</p>

... In our cohort, AS-OCT showed a characteristic appear- ance of CSCC in all cases helping not only the diagnosis of primary and postoperative subclinical, persistent or recurrent cases, but also monitoring postoperative ...

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Single early instillation of mitomycin C and urinary alkalinization in low-risk non-muscle-invasive bladder cancer: a preliminary study

Single early instillation of mitomycin C and urinary alkalinization in low-risk non-muscle-invasive bladder cancer: a preliminary study

... intracavitary MMC diluted with 40 mL of sterile saline, given into a completely empty bladder in the first 6 hours postopera- tively via a Foley catheter inserted during the operation, and the solution was kept in ...

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Preoperative subconjunctival combined injection of bevacizumab and mitomycin C before the surgical excision of primary pterygium: clinical and histological results

Preoperative subconjunctival combined injection of bevacizumab and mitomycin C before the surgical excision of primary pterygium: clinical and histological results

... All the excised tissues were sent for histological and immunohistological analyses. The findings were compared with the histological features of pterygia of two patients who did not have preoperative injection of Avastin ...

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 PHYTOSOME LOADED NOVEL HERBAL DRUG DELIVERY SYSTEM: A REVIEW

 PHYTOSOME LOADED NOVEL HERBAL DRUG DELIVERY SYSTEM: A REVIEW

... Zhenqing Hou et al.24 developed phytosomes loaded with mitomycin C-Soybean phosphatidylcholine MMC−SPC complex MMC-loaded phytosomes by a solvent evaporation method combined with a nano [r] ...

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Pharmacokinetics of Mitomycin C Following Hepatic Arterial Chemoembolization With Gelfoam

Pharmacokinetics of Mitomycin C Following Hepatic Arterial Chemoembolization With Gelfoam

... In the first group, gelfoam supplemented with mitomycin C (MMC) was injected into the hepatic artery, whereas the second group received a hepatic arterial injection of MMC solution alone[r] ...

10

Risk factors for choroidal detachment after trabeculectomy with mitomycin C

Risk factors for choroidal detachment after trabeculectomy with mitomycin C

... junctival flap was created by a fornix-based incision; the creation of the scleral flap was a half-layer single flap. The concentration and the incubation of MMC were 0.4 mg/mL and 4 minutes, respectively. The ...

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Effects of Chinese herbal medicine in combination with mitomycin C on gastric cancer cells

Effects of Chinese herbal medicine in combination with mitomycin C on gastric cancer cells

... cell, MMC has been shown to induce apoptosis by a caspase-dependent mechanism ...to MMC further enhances MMC-induced apoptosis ...with MMC in human gastric cancer cell line, ...enhanced ...

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Chronification of Tympanic Perforation with Mitomycin C in a Rat Model

Chronification of Tympanic Perforation with Mitomycin C in a Rat Model

... or mitomycin C (4, 5), but laser equipment is not a common tool in research ...of mitomycin C alone or in combination with dexamethasone may produce a chronic tympanic perforation model in ...

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THE INDUCTION OF MITOTIC RECOMBINATION BY MITOMYCIN C IN USTILAGO AND SACCHAROMYCES

THE INDUCTION OF MITOTIC RECOMBINATION BY MITOMYCIN C IN USTILAGO AND SACCHAROMYCES

... cell is later than in the mitotic one (see HENDERSON 1962), it is suggested that this inhibition pushes the mitotic cell towards the meiotic condition, thus bring- ing a[r] ...

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EFFECTS OF MITOMYCIN C ON CROSSING OVER IN DROSOPHILA MELANOGASTER

EFFECTS OF MITOMYCIN C ON CROSSING OVER IN DROSOPHILA MELANOGASTER

... and HOLLIDAY (1964) find that treatment of Ustilago and Saccharomyces with agents that inhibit DNA replication (mitomycin C, 5-fluorodeoxyuridine) results in increased somat[r] ...

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