MMP-7
Serum MMP-7 in the Diagnosis of Biliary Atresia
... that MMP- 7 was superior to all other potential biomarkers and had a signi fi cantly higher concentration in patients with BA when compared with non-BA using a high-throughput proteomic assay ...serum ...
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R) promotes colorectal cancer metastasis by regulating Axin1/β-catenin/MMP-7 signaling pathway
... of mice treated with GR127935 compared with that of the control group. Similar to the result in vitro, the levels of β-catenin, LEF1, TCF4 and MMP-7 increased after treatment with GR127935 compared with ...
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Protein Expression of STAT3, pSTAT3, MMP 7 and VEGF in Colorectal Adenocarcinoma: An Immunohistochemical Study
... In the present study we have examined the expression of STAT3, pSTAT3, MMP-7 and VEGF protein by im- munohistochemistry in a cohort of colorectal adenocarcinomas. There was overexpression of STAT3 in 26.7% ...
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Original Article miR-21 targets MMP-7 and promotes perineural invasion of cholangiocarcinoma
... bly MMP-7 and -9, are associated with tumor invasion and metastasis in malignant neopla- sms, including intrahepatic cholangiocarcino- ma ...Unlike MMP-9, which is expressed in both the carcinoma and ...
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Matrix metalloproteinase (MMP) 7 in Barrett’s esophagus and esophageal adenocarcinoma : expression, metabolism and functional significance
... how MMP-7 expression changes in the progression to esophageal adenocarcinoma (EAC), and have studied mechanisms regulating its expression and its functional ...that MMP-7 was weakly expressed ...
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Original Article Clinical impact and prognostic value of CD147 and MMP-7 expression in patients with pancreatic ductal adenocarcinoma
... of MMP-7 in pancreatic can- cer patients ...of MMP-7 is not significantly different in neoplastic and non- neoplastic ...of MMP-7 in cancer cell is significantly correlated with ...
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Plasma levels of MMP-7 and TIMP-1 in laboratory diagnostics and differentiation of selected histological types of epithelial ovarian cancers
... [18]. MMP-7 (matrilysin) is the smallest proteinase from the entire metalloproteinases family with broad proteolytic activity against proteogly- cans, elastin, laminin, collagens ...
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Original Article Associations of polymorphisms in MMP-7 and MMP-8 with osteoarthritis risk in a Han Chinese population
... of MMP-7 in human osteoarthritic synovial membrane and shown increased expression of MMP8 in human osteoarthritic ...of MMP-7 and MMP-8 polymorphisms with osteoarthritis susceptibility, ...
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Tubular injury triggers podocyte dysfunction by β-catenin–driven release of MMP-7
... exogenous MMP-7 in vivo induces ...for MMP-7 in mediating podocyte injury in vivo, we examined the effect of MMP-7 overexpression on the integrity of the glomerular filtration ...
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Detection of serum MMP-7 and MMP-9 in cholangiocarcinoma patients: evaluation of diagnostic accuracy
... eases. MMP-7 is the smallest of the MMPs and has been demonstrated to degrade or process a variety of matrix and nonmatrix ...cells, MMP-7 is principally expressed by epithelial cells ...serum ...
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TIMP-2 decreases the invasive potential of MCF-7 and MDAMB-231 cells independent of MMP inhibition
... of MMP-7 and MMP-21, all other MMPs contain a C-terminal hemopexin-like domain that dictates substrate specificity and mediates interactions with other ...(MT-1 MMP to MT-4 MMP) are ...
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Limited independent prognostic value of MMP-14 and MMP-2 expression in ovarian cancer
... as MMP-2, MMP-7, MMP-9, MMP-11 and MMP-14 has been reported and correlated with invasion and metasta- sis ...of MMP-14 has been demonstrated in ovarian clear-cell ...[9]. ...
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Expression of the metalloproteases MMP 1, MMP 2, MMP 3, MMP 9, MMP 11, TIMP 1 and TIMP 2 in angiocentric midfacial lymphomas
... of MMP-9 and MMP-2 ...of MMP-2, for a ternary complex with proMMP- 2 and MT1-MMP ...lines, MMP-9 is induced by the EBV latent membrane protein-1 (LMP-1), particu- larly in Burkitt's ...
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Expression of MMP-2, MMP-9 and TIMP-1 in the Wall of Abdominal Aortic Aneurysms
... This study analyzed the relationship between the development of AAAs and the expression of MMP-2, MMP-9 and TIMP-1 in the aortic walls. The AAAs were subclassified into 2 categories due to the diameter of ...
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The influence of MMP 14, TIMP 2 and MMP 2 expression on breast cancer prognosis
... of MMP-2 expression is not clear in the ...high MMP-2 mRNA or protein expression levels and a poor out- ...cases, MMP-2 overexpres- sion predicted a 15% greater risk of recurrence [15] but the ...
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MMP-1 ) in the normal human
... Skin aging is caused by external and internal factors [1, 2]. A common feature of aging process is the creation of wrinkles [3]. Wrinkling is mostly caused by destruction of the extracellular matrix (ECM) in the dermis. ...
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P> 0.05). Significantly higher levels of serum MMP-2, MMP-9, TIMP-1
... detect MMP and TIMP mRNA and protein levels in residual spleen samples and ...groups, MMP-2, MMP-9, TIMP-1 and TIMP-2 expression were densely distributed in ...for MMP-2, MMP-9, TIMP-1 ...
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Original Article MMP-2 and MMP-9 gene polymorphisms associated with cervical cancer risk
... the MMP-2 gene consists of 13 exons and 12 introns, and structural genes thereof have a total length of 27 kb ...of MMP-2 occurs in various different levels such as tran- scription, secretion, the ...
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Inhibition of MMP-2 and MMP-9 activities by solvent-partitioned Sargassum horneri extracts
... of MMP-2 and MMP-9 were determined by RT-PCR and im- munoblotting with the levels of TIMP-1 and ...of MMP-2 in some presented situations (Jiao et ...of MMP-2 and MMP-9 in terms of both ...
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Early and Late Changes of MMP 2 and MMP 9 in Bleomycin Induced Pulmonary Fibrosis
... active MMP did not necessarily correlate to total MMP ...only MMP-2, but not MMP-9, was detected in later phase of fibrosis is in accordance with an another study which showed similar result, ...
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