MMPs, matrix metalloproteinases
Effect of taurine chloramine on the production of matrix metalloproteinases (MMPs) in adiponectin- or IL-1β-stimulated fibroblast-like synoviocytes
... as matrix metalloproteinases (MMPs) and reactive oxygen inter- mediates such as nitric oxide (NO) and hypochlorous acid (HOCl) for intracellular digestion during phagoc- ytosis ...
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Role of matrix metalloproteinases (MMPs) and MMP inhibitors on intracranial aneurysms: a review article
... Most MMPs are not expressed at high or detectable levels in the adult central nerv- ous system ...whole, MMPs are mainly not detectable in the normal CNS and their excess has been observed in some neuro- ...
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The role and control of matrix metalloproteinases (MMPs) in equine cutaneous wounds: a focus on both endogenous and exogenous proteases
... 2001). MMPs may play a role in this fibrinolytic pathway, allowing the epidermal cells to migrate across the wound ...and MMPs in wound healing with the residual wound healing capacity observed in the ...
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An in silico based characterization and analysis of Human matrix metalloproteinases (MMPs)
... All MMPs Analysis of amino acid composition indicates that while the percentage of cysteine residues in majority of MMPs lies in the range of ...these MMPs in pathological ...these MMPs may be ...
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Serum prolidase activity is associated with non-diabetic metabolic syndrome
... syndrome; MMPs: Matrix metalloproteinases; OGTT: Oral glucose tolerance test; NCEP: National Cholesterol Education Program; BMI: Body mass index; SBP: Systolic blood pressures; DBP: Diastolic blood ...
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Essential role of mitogen activated protein kinases in IL 17A induced MMP 3 expression in human synovial sarcoma cells
... Abbreviations IL-17A: interleukin-17A; MMPs: matrix metalloproteinases; ECM: extracellular matrix; MAPK: mitogen-activated protein kinase; ERK1/2: extracellular signalregulated kinase ½;[r] ...
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Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathy
... Extracellular matrix; AGE: Advanced glycation end products; RAGE: Receptor for AGE; MMPs: Matrix metalloproteinases; RAS: Renin-angiotensin system; ACE: Angiotensin-converting enzyme; Ang II: ...
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Effect of serum-containing and serum-free culture medium-mediated activation of matrix metalloproteinases on embryonic developmental competence
... serum-free medium was lower than that in serum- containing medium. In particular, the expression of MMP-2 was increased in the cytoplasm after in vitro fertilization, and the activity of MMP-2 was higher than that in the ...
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MMP16 is a marker of poor prognosis in gastric cancer promoting proliferation and invasion
... Matrix metalloproteinases (MMPs) are closely associated with tumor proliferation, invasion and ...the MMPs expression and their clinical significances in gastric cancer ...studied MMPs ...
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Alterative effects of an oral alginate extract on experimental rabbit osteoarthritis
... proinflammatory matrix metalloproteinases (MMPs) including MMP1, MMP3 and MMP13 in a dose-dependent manner and increased the mRNA level of aggrecan, the major proteoglycan in articular cartilage, at ...
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Dietary red palm oil supplementation decreases infarct size in cholesterol fed rats
... Matrix metalloproteinases (MMPs) are calcium and zinc dependent endopeptidases. Under normal physiological conditions they facilitate cell migration and tissue remo- deling [13]. Recently it was ...
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Orthobiologic Treatment for Knee Osteoarthritis: A Cost Effectiveness Choice
... release Matrix Metalloproteinases (MMPs), known to be capable of degrading collagen type II ...extracellular matrix (collagen) allows the migration and invasion of endothelial cells during the ...
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Matrix metalloproteinases and their inhibitors in cardiovascular pathologies: current knowledge and clinical potential
... may be attributable to a myriad of factors, including an inadequate dosing regime and a poorly selected end point. Indeed, the plasma profiles achieved in patients receiving PG11680 were not reported, casting further ...
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Matrix metalloproteinase-9 in the pathophysiology and diagnosis of dry eye syndrome
... of matrix metalloproteinases (MMPs), particularly MMP-9, have been detected in the tears and ocular surface epithelial and inflammatory cells in dry ...eye. MMPs have been found to participate ...
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Effects of transcutaneous electrical nerve stimulation (TENS) on arterial stiffness and blood pressure in resistant hypertensive individuals: study protocol for a randomized controlled trial
... and matrix metalloproteinases (MMPs), resulting in increased inflammatory cell recruitment, the migration and proliferation of endothelial cells, platelet aggregation, and the release of free ...
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Short Link N promotes disc repair in a rabbit model of disc degeneration
... by matrix metalloproteinases (MMPs) during tissue turnover in vivo [29] and has been shown to enhance proteoglycan synthesis by IVD cells and intact human discs, and also to increase disc height in a ...
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RHEUMATOID ARTHRITIS : AN UNDERSTANDING IN THE LIGHT OF HERBAL MEDICINES
... of matrix metalloproteinases (MMPs), enzymes produced by activated macrophages and fibroblasts in response to pro-inflammatory cytokines such as IL-1 and ...
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Matrix metalloproteinases and epileptogenesis
... Transsynaptic activation of NMDA receptors in neurons leads to activation of the ERK1/2 and PI3 kinase pathways [18]. The hypothesis has been formulated that, in the con- text of evolving epilepsy, pathological ...
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Matrix metalloproteinases in the wound microenvironment: therapeutic perspectives
... Abstract: Matrix metalloproteinases (MMPs) are key effector molecules responsible for extracellular matrix (ECM) ...for MMPs are ECM components, they are also able to digest a variety ...
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Host Modulation Therapy - Restriction of Periodontal Destruction
... The use of modulating agents, including inhibition of matrix metalloproteinases (MMPs) with antiproteinases, blocking production of proinflammatory cytokines and prostaglandins with anti[r] ...
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