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model organism

Similarity-based search of model organism, disease and drug effect phenotypes

Similarity-based search of model organism, disease and drug effect phenotypes

... There are several further related tools that use similar algorithms and perform similar analyses. In particular, the Phenomizer [34] is a tool for diagnosing patients based on semantic similarity searchers over OMIM dis- ...

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Model organism databases: essential resources that need the support of both funders and users

Model organism databases: essential resources that need the support of both funders and users

... In addition to fulfilling their original mandate to support specific model species, the experimental annotations that MODs create yield benefits that reach far beyond model organism research ...

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Effect of Dopamine on Alzheimer and Autism and Determination of Best Model Organism for Both

Effect of Dopamine on Alzheimer and Autism and Determination of Best Model Organism for Both

... Abstract- As medicinal science heading towards the new discoveries, butthe trap of psychological disorders, kept questioning about the capabilities of medicinal science. They sinisterly kill people through their slow ...

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The Alliance of Genome Resources: Building a Modern Data Ecosystem for Model Organism Databases

The Alliance of Genome Resources: Building a Modern Data Ecosystem for Model Organism Databases

... most organism-specific gene, phenotype, and disease annotations (Table ...(Model organism Aggregated Resources for Rare Variant ExpLoration) (Wang et ...

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The regenerative flatworm Macrostomum lignano, a model organism with high experimental potential

The regenerative flatworm Macrostomum lignano, a model organism with high experimental potential

... rising model organism for this type of research, and its power stems from a unique set of biological properties combined with amenability to experimental ...this model organism for different ...

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The Mouse Lemur, a Genetic Model Organism for Primate Biology, Behavior, and Health

The Mouse Lemur, a Genetic Model Organism for Primate Biology, Behavior, and Health

... ABSTRACT Systematic genetic studies of a handful of diverse organisms over the past 50 years have transformed our understanding of biology. However, many aspects of primate biology, behavior, and disease are absent or ...

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Influence of temperature on development, reproduction and regeneration in the flatworm model organism, Macrostomum lignano

Influence of temperature on development, reproduction and regeneration in the flatworm model organism, Macrostomum lignano

... Here we present how temperature affects development, growth, fertility, and regeneration capabilities of Macrosto- mum lignano. We tested the stress response to elevated temperatures by measuring the activity of the Heat ...

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Oxidative damage prevention of DNA using passion fruit extract in earthworm as model organism

Oxidative damage prevention of DNA using passion fruit extract in earthworm as model organism

... the organism´s capacity to manage those using endogenous and exogenous ...animal model organism to study the oxidative DNA damage, regeneration, stem cells, wound healing, soil toxicology, ...

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Drosophila melanogaster as an alternative model organism in nutrigenomics

Drosophila melanogaster as an alternative model organism in nutrigenomics

... well-suited model organism to unravel these interactions in the context of nutrigenomics as it combines several advantages including an affordable maintenance, a short generation time, a high fecundity, a ...

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Publication Trends in Model Organism Research

Publication Trends in Model Organism Research

... of model organisms within the laboratory, in fact, may render them insensitive to environmental variation and hence atypical in a problematic ...on model organisms for placing undue empha- sis on ...

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Drosophila melanogaster as a model organism for Alzheimer’s disease

Drosophila melanogaster as a model organism for Alzheimer’s disease

... ideal organism to study neurodegenerative diseases like AD ...reasonable organism to study specific aspects of AD ...powerful model to study the molecular basis of neuronal decline in the context of ...

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The vertebrate taxonomy ontology: a framework for reasoning across model organism and species phenotypes

The vertebrate taxonomy ontology: a framework for reasoning across model organism and species phenotypes

... This is a result of three factors: (1) the PaleoDB taxonomic data must be grafted at many differ- ent nodes otherwise represented by extant species from other sources because extinct tax[r] ...

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Genetic variation in neurodegenerative diseases and its accessibility in the model organism Caenorhabditis elegans

Genetic variation in neurodegenerative diseases and its accessibility in the model organism Caenorhabditis elegans

... reasons. Model organisms such as yeast, insects, worms, fish, and rodents are therefore critical to furthering our understanding of differences between individual in ...in model species with different gen- ...

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Developmental biology and potential use of Alboglossiphonia lata (Annelida: Hirudinea) as an “Evo-Devo” model organism

Developmental biology and potential use of Alboglossiphonia lata (Annelida: Hirudinea) as an “Evo-Devo” model organism

... The developmental process observed in A. lata em- bryos is overall similar to that observed in the model or- ganisms H. austinensis and other studied glossiphoniidae leech species. Aggregated groups of mature ...

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Computational and Statistical Analyses of Insertional Polymorphic Endogenous Retroviruses in a Non-Model Organism

Computational and Statistical Analyses of Insertional Polymorphic Endogenous Retroviruses in a Non-Model Organism

... evolutionary model to construct a population tree, has been shown to exhibit favorable statistical properties in situations for which the MrBayes approach taken here could fail ...evolutionary model based ...

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The influence of disease categories on gene candidate predictions from model organism phenotypes

The influence of disease categories on gene candidate predictions from model organism phenotypes

... The common urogenital and other types of clinical phenotypes all matched the expected mouse phenotypes in Mammalian Phenotype Ontology (MP) (and their more specific child terms when present) with the exception of ...

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Digital dissection of the model organism Xenopus laevis using contrast-enhanced computed tomography

Digital dissection of the model organism Xenopus laevis using contrast-enhanced computed tomography

... Dorsal aspect of proximal femur, between insertions of outer and extra middle layers of M. iliacus internus II Lateral, ventral and medial aspects of posterior iliac shaft. Anterodor[r] ...

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Bio-evaluation of functional date bars using rats as model organism against hypercholesterolemia

Bio-evaluation of functional date bars using rats as model organism against hypercholesterolemia

... obesity which is a major heath threatening risk factor [8]. It is the need of time to produce foods with high nutri- tional quality that could be useful in providing the ne- cessary nourishment and combating malnutrition ...

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Genetic transformation of Knufia Petricola A95 - a model organism for biofilm-material interactions

Genetic transformation of Knufia Petricola A95 - a model organism for biofilm-material interactions

... a model biofilm compris- ing the cyanobacterium Nostoc punctiforme and the MCF Knufia petricola (A95) as a new test system for the simulation of environment-biofilm interactions and their impact on ...experimental ...

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Drosophila as a new model organism for the neurobiology of
aggression?

Drosophila as a new model organism for the neurobiology of aggression?

... The experimental males were manipulated in one of various ways: by a classical mutation affecting βalanine levels, a P-element mutation affecting octopamine levels, or insertion of trans[r] ...

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