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Molecular Mechanism

Antiproliferative and molecular mechanism of eugenol-induced apoptosis in cancer cells

Antiproliferative and molecular mechanism of eugenol-induced apoptosis in cancer cells

... the molecular mechanism of eugenol-induced apoptosis in melanoma, skin tumors, osteosarcoma, leukemia, gastric and mast cells has been well ...and molecular mechanism of the eugenol-induced ...

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A molecular mechanism for diacylglycerol-mediated promotion of negative caloric balance

A molecular mechanism for diacylglycerol-mediated promotion of negative caloric balance

... Conclusions: Our study demonstrated that 1-monoacylglycerol, a digestive product of DAG, increases serotonin release from the Caco-2 cells, and enhances expression of genes associated with β-oxidation, FA metabolism, and ...

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Molecular Mechanism Study of Vitorgan Cell Molecular
Therapy

Molecular Mechanism Study of Vitorgan Cell Molecular Therapy

... In this study, we focused onunderstanding the cytokine composition of concentrated vitOrganinjection solutionby using cytokine antibody array. As a result, a list of 123 molecules was found in the concentrated injection ...

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Molecular Mechanism for LAMP1 Recognition by Lassa Virus

Molecular Mechanism for LAMP1 Recognition by Lassa Virus

... LAMP1 (250 nM versus 500 nM NaCl) (data not shown). This observation implies that polar interactions, as predicted for the histidine triad, are important for binding. Altogether, we can con- clude that the histidine ...

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Molecular mechanism of transcriptional activation by oestrogen receptor alpha

Molecular mechanism of transcriptional activation by oestrogen receptor alpha

... confers selective binding to E2 since it would not accommodate the hydrogen bond accepting 3-keto group at the A -ring o f other steorid horm ones, such as progesterone. Although the ER antagonists, Tamoxifen and ...

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Molecular mechanism of activated T cells in breast cancer

Molecular mechanism of activated T cells in breast cancer

... Activated T cells may play an important role in the defense response to other organism function and herpes simplex infection pathway by upregulating IL6 and STAT1, which further affect the progression of BC. Furthermore, ...

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The physiological and molecular mechanism of brassinosteroid in response to stress: a review

The physiological and molecular mechanism of brassinosteroid in response to stress: a review

... the enzymes CAT, POD, carbonic anhydrase, and NR are also enhanced by BR under nickel stress in mungbean [6, 83, 85]. BR enhance the enzyme activities of antioxidants [CAT, POD, SOD, GR (glutathione reductase)], increase ...

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Molecular mechanism of imprinting of the maize endosperm gene fie1

Molecular mechanism of imprinting of the maize endosperm gene fie1

... DUPLICATED FIE GENES IN MAIZE: EXPRESSION PATTERN AND IMPRINTING SUGGEST DISTINCT FUNCTIONS Abstract Introduction Results Genomic structure offie loci The maize fie genes have distinct p[r] ...

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The Fas Counterattack: A Molecular Mechanism of Tumor Immune Privilege

The Fas Counterattack: A Molecular Mechanism of Tumor Immune Privilege

... The possibility that FasL might be ex- pressed by nonlymphoid tumors as a mediator of immune escape was initially raised by the finding that some colon cancer cell lines expressed FasL ([r] ...

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Reovirus oncolysis: a brief insight on molecular mechanism and immunological aspect

Reovirus oncolysis: a brief insight on molecular mechanism and immunological aspect

... cytolytic effects on transformed in vitro, its implementation in vivo in animal models or in patient studies has encountered a mixed success. It is hypothesized that the main factor that determines the efficiency of ...

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The Molecular Mechanism of Autophagy

The Molecular Mechanism of Autophagy

... as organelle turnover. Although autophagy is primarily viewed as a nonspecific bulk degradation process, a related organelle degradation pathway involved in peroxisome degradation, pexo- phagy, appears to be a highly ...

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On the molecular mechanism of GC content variation among eubacterial genomes

On the molecular mechanism of GC content variation among eubacterial genomes

... the molecular basis of the GC-content variation in bac- ...the molecular mechanisms underlying the mutational bias and especially the selective factors that offset this bias are of major interest but I am ...

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STUDY THE MOLECULAR MECHANISM OF SALVIA SPECIES IN PREVENTION OF DIABETES

STUDY THE MOLECULAR MECHANISM OF SALVIA SPECIES IN PREVENTION OF DIABETES

... Flavonoids, in particular, have a positive effect on diabetes, by acting an inhibitory effect on the aldose reductase enzyme that may play a role in the complications of diabetes 7 . Quercetin reduces glucose and ...

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Metformin in colorectal cancer: molecular mechanism, preclinical and clinical aspects

Metformin in colorectal cancer: molecular mechanism, preclinical and clinical aspects

... the molecular mechanisms of metformin in CRC models (discussed in later ...its molecular mechanisms that justify its repurposed use as a pro- spective and potential medicament in the intervention of CRC ...

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Molecular mechanism of ligand recognition by membrane transport protein, Mhp1

Molecular mechanism of ligand recognition by membrane transport protein, Mhp1

... a mechanism described by the “alter- nating access” model of membrane transport (Jardetzky, 1966) with their similar structures implying commonalities of mechanism (Abramson & Wright, 2009; ...

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Study of the molecular mechanism of decreased liver synthesis of albumin in inflammation

Study of the molecular mechanism of decreased liver synthesis of albumin in inflammation

... decreased synthesis could not be related to a reduced amino acid supply, we have also examined the possible molecular mechanisms of reduced albumin synthesis during inflammation using in vivo and in vitro ...

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Molecular mechanism of transcriptional activation of angiotensinogen gene by proximal promoter

Molecular mechanism of transcriptional activation of angiotensinogen gene by proximal promoter

... the molecular relationship between the transcriptional regulation of the angiotensinogen gene and the pathogenesis of hypertension, we have analyzed the basal promoter of the angiotensinogen ...

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Beneficial Impact and Molecular Mechanism of Bacillus Coagulans on Piglets Intestine

Beneficial Impact and Molecular Mechanism of Bacillus Coagulans on Piglets Intestine

... The cellular response to viral infection includes the induction of genes for type I interferons, IFN-α and IFN-β, which are produced in most cell types and play a vital role in innate resistance to viral and bacterial ...

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Molecular mechanism of ligand recognition by membrane transport protein, Mhp1

Molecular mechanism of ligand recognition by membrane transport protein, Mhp1

... the molecular basis of the alternating access ...crystallography, molecular dynamics, site-directed mutagenesis, biochemical/biophysical assays, and the design and synthesis of novel ...the molecular ...

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Reaction intermediates and molecular mechanism of Peroxynitrite activation by NO synthases

Reaction intermediates and molecular mechanism of Peroxynitrite activation by NO synthases

... to the ferric state within seconds suggesting that I435 disappearance may be linked to other secondary reactions as well. How photoreduction of such a complex mixture may trap a Cpd-I state at relatively high-yield is ...

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