Mouse Colon
Mast cells and histamine contribute to bile acid stimulated secretion in the mouse colon
... Certain dihydroxy bile acids cause secretory diarrhea when present in the colonic lumen at inappropriately high concentrations. However, the mechanism underlying the secretagogue activity has not been fully elucidated. ...
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Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer
... different mouse models of CRC were compared for model-specific differences, then compared to mouse colon development stages, and then to human CRC samples (Figure ...The mouse tumor sample ...
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Ethanol extract of Chrysanthemum zawadskii Herbich induces autophagy and apoptosis in mouse colon cancer cells through the regulation of reactive oxygen species
... Fig. 4 Reactive oxygen species (ROS) regulated apoptosis and autophagy induced by ethanol extracts of Chrysanthemum zawadskii Herbich (ECZ) in mouse colon cancer CT-26 cells. a Representative histogram of ...
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A Crypt Specific Core Microbiota Resides in the Mouse Colon
... the mouse gastrointestinal tract, we targeted molecular microbial diagnostics of the crypts that contain the intestinal stem cells, which account for epithelial regener- ...the mouse and that regardless of ...
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Bestrophin 2 mediates bicarbonate transport by goblet cells in mouse colon
... MPO activity. Neutrophil infiltration was quantified by measuring MPO activity. Colon samples were homogenized in 1:20 (w/v) of 50 mM phosphate buffer (pH 6.0) containing 0.5% hexadecyltrimethyl ammo- nium bromide ...
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Extract of Ginkgo biloba exacerbates liver metastasis in a mouse colon cancer Xenograft model
... each mouse was anesthetized using isoflurane/oxygen gas from a vaporizer and placed face-up on a height-adjustable tray in the imaging system for whole body ...
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Glucagon-like peptide-1 exerts anti-inflammatory effects on mouse colon smooth muscle cells through the cyclic adenosine monophosphate/nuclear factor-κB pathway in vitro
... by mouse CSMCs using antibody array ...CSMC, colon smooth muscle cell; Ex 50, exendin-4 (50 nM); Ex 100, exendin-4 (100 nM); GCSF, granulocyte colony stimulating factor; GM-CSF, granulocyte– macrophage ...
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Anti-metastatic effect of the TM4SF5-specific peptide vaccine and humanized monoclonal antibody on colon cancer in a mouse lung metastasis model
... and colon cancer in a mouse ...CT-26 mouse colon cancer cell line into mice induced tumors in the ...in mouse metastasis ...against colon cancer in ...
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Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer
... Human cancer cells frequently have regions of their DNA hypermethylated, which results in transcriptional silencing of affected genes and promotion of tumor formation. However, it is still unknown whether cancer- ...
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Cloning of the mouse hepatitis virus (MHV) receptor: expression in human and hamster cell lines confers susceptibility to MHV.
... A segment of cDNA from BALB/c mouse colon was amplified by RNA polymerase chain reaction PCR by using degenerate oligonucleotide primers on the basis of the N-terminal amino acid sequenc[r] ...
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Cationized dextran nanoparticle-encapsulated <em>CXCR4</em>-siRNA enhanced correlation between <em>CXCR4</em> expression and serum alkaline phosphatase in a mouse model of colorectal cancer
... the colon and distal ileum. Specimens of mouse colon and ileum were studied immunohistochemically for the presence of CXCR4 (integral membrane ...the colon and distal ileum showed strong ...
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Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon
... in mouse colon tumors and normal ...DMH-induced colon tumors (see ...from mouse spleen at 6 h, as reported earlier ...A colon tumor from DMH-treated mice was included as a reference ...
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The 15kDa Selenoprotein and Thioredoxin Reductase 1 Promote Colon Cancer by Different Pathways
... in mouse colon cancer cells demonstrate that differences in cell cycle regu- lation may have partially contributed to reversals of the observed cancer ...in mouse [18] and human colon cancer ...
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Sulindac activates NF-κB signaling in colon cancer cells
... Treatment of mice for 1 week with sulindac also resulted in significant up-regulation of other NF-κB target genes IL- 1β, iNOS and Cox-2 as well as c-Fos in the colon mucosa. This suggests that sulindac induces an ...
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Effects of urban coarse particles inhalation on oxidative and inflammatory parameters in the mouse lung and colon
... in colon TNFα and IFNγ protein levels have also been reported following 10 and 14 weeks of oral coarse PM intoxication in mice starting from the neo- natal period ...
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Murine colon proteome and characterization of the protein pathways
... pattern. Following construction of the colon proteome catalogue, protein abundance was fallen within the range from 1.2 x 10 -5 to 1.8 x 10 -2 . This wide dynamic range fur- ther attests our unbiased Lc-Ms ...
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Vitamin D3 enhances the tumouricidal effects of 5-Fluorouracil through multipathway mechanisms in azoxymethane rat model of colon cancer
... Pathological alterations in several molecular pathways have been identified in the tumorigenesis of colon can- cer. These molecules include transforming growth factor (TGF)-β and its related molecules, ...
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A benign cultured colon adenoma bears three genetically altered colon cancer oncogenes, but progresses to tumorigenicity and transforming growth factor beta independence without inactivating the p53 tumor suppressor gene
... a colon adenoma cell line to tumorigenicity and growth factor ...of colon cancer suppressor genes and oncogenes. VACO-235, a human colon adenoma cell line, is at early passages nontumorigenic in the ...
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Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo
... human colon carcinoma ...of colon carcinoma cells, we generated stable transfected clones expressing an antisense cDNA target- ing domain III of perlecan ...
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Vol 7, No 11-12 (2018)
... decapitation colon is excised opened longitudinally, rinsed with saline, and the length was measured and considered as an additional index for colitis, as well as mаcroscopic damage of the colonic mucosa scored ...
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