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Mouse embryonic stem cells (ESCs)

TET dependent regulation of retrotransposable elements in mouse embryonic stem cells

TET dependent regulation of retrotransposable elements in mouse embryonic stem cells

... Results: We performed a detailed investigation of the role of TET enzymes in the regulation of TEs in mouse embryonic stem cells (ESCs). We find that TET1 and TET2 bind multiple TE classes ...

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Zscan4 Is Activated after Telomere Shortening in Mouse Embryonic Stem Cells

Zscan4 Is Activated after Telomere Shortening in Mouse Embryonic Stem Cells

... during mouse development. In vitro, it is transiently expressed in mouse embryonic stem cells (ESCs), only in 5% of the population at one ...

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Live imaging of ERK signalling dynamics in differentiating mouse embryonic stem cells

Live imaging of ERK signalling dynamics in differentiating mouse embryonic stem cells

... in mouse embryonic stem cells ...individual cells during this transition is ...single mouse ESCs during ...single cells within ESC ...single cells during ...

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Generation of thalamic neurons from mouse embryonic stem cells

Generation of thalamic neurons from mouse embryonic stem cells

... from mouse embryonic stem cells (mESCs) by modifying the default method that induces the most-anterior neural type in self-organizing ...

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Specialized mouse embryonic stem cells for studying vascular development

Specialized mouse embryonic stem cells for studying vascular development

... Dovepress Mouse embryonic stem cells and vascular development order to disaggregate the ...nonadherent cells (approximately 5–10 minutes of attentive observation under microscope), the ...

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Mapping molecular pathways for embryonic Sertoli cells derivation based on differentiation model of mouse embryonic stem cells

Mapping molecular pathways for embryonic Sertoli cells derivation based on differentiation model of mouse embryonic stem cells

... Sertoli cells [26–30]. Thus, in our former work, we have induced embryonic Sertoli-like cells (eSLCs) from mouse embryonic stem cells (mESCs) by overexpression of Wt1, ...

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Differentiating mouse embryonic stem cells express markers of human endometrium

Differentiating mouse embryonic stem cells express markers of human endometrium

... Keywords: Mouse embryonic stem cells, Endometrium, Differentiation, Animal model, Endometriosis Background Endometriosis is a chronic, hormone-dependent, inflam- matory condition marked by ...

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The role of Importin-βs in the maintenance and lineage commitment of mouse embryonic stem cells

The role of Importin-βs in the maintenance and lineage commitment of mouse embryonic stem cells

... in mouse embryonic stem cells (mESCs), mouse embryonic fibroblast (MEF) and mESCs differentiated into neural ectoderm (NE) or mesoendoderm ...

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EXAMINATION OF THE GERM CELL CHIMERA FORMING POTENTIAL OF MOUSE EMBRYONIC STEM CELLS

EXAMINATION OF THE GERM CELL CHIMERA FORMING POTENTIAL OF MOUSE EMBRYONIC STEM CELLS

... of mouse embryonic stem cells (ES ...R1/E mouse ES cell ...derived cells could contribute to the germ ...aneuploid cells, in R1 ES cell line, dramatically increased after ...

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Assessment of Biological Properties of Mouse Embryonic Stem Cells Characteristics Prior To Differentiation

Assessment of Biological Properties of Mouse Embryonic Stem Cells Characteristics Prior To Differentiation

... of Mouse Embryonic Stem Cells Characteristics Prior to Differentiation 387 formation can be variable and can have marked effects on the subsequent ...both mouse and human ES ...

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Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency

Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency

... individual cells, but a thorough characterization of these fluctuations and their impact on the pluripotent state is still ...in mouse embryonic stem cells (mESCs), and to dissect the ...

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Differentiation roadmap of embryonic Sertoli cells derived from mouse embryonic stem cells

Differentiation roadmap of embryonic Sertoli cells derived from mouse embryonic stem cells

... mES cells grow and spontaneously differentiate into three germ layers under an environ- ment without ...somatic cells in the coelomic epithelium develops into SF1-positive precursor cells with the ...

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Germline potential of parthenogenetic haploid mouse embryonic stem cells

Germline potential of parthenogenetic haploid mouse embryonic stem cells

... Haploid embryonic stem cells (ESCs) have recently been derived from parthenogenetic mouse embryos and offer new possibilities for genetic ...transgenic mouse strains from genetically ...

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Prediction of Polycomb target genes in mouse embryonic stem cells

Prediction of Polycomb target genes in mouse embryonic stem cells

... Enrichment of TF binding and motif sites in PcG target genes Numerous groups have previously applied ChIP-chip/seq methods to identify genome-wide locations of PcG and H3K27me3 targets in mouse ESCs [7,9 –15] . ...

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Molecular regulation of Polycomb complexes in mouse embryonic stem cells

Molecular regulation of Polycomb complexes in mouse embryonic stem cells

... preimplantation mouse embryos by DNase I sequencing has shown that chromatin accessibility at regulatory regions increases progressively during development, with the proximal promoters being the earliest ...

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Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cells

Temporal specification of blood progenitors from mouse embryonic stem cells and induced pluripotent stem cells

... – cells generated from either T-EGFP ESCs (columns 1+2) or Sox17-EGFP ESCs (column 3) were isolated, reaggregated in the indicated conditions for 48 hours and then analyzed for expression of T-EGFP, Sox17-EGFP, ...

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Cellular heterogeneity in the level of mtDNA heteroplasmy in mouse embryonic stem cells

Cellular heterogeneity in the level of mtDNA heteroplasmy in mouse embryonic stem cells

... In ESCs, inter-colony heterogeneity varied up to 61%, whereas intra-colony heterogeneity varied up to 100%. Three out of five cell lines displayed nearly homoplasmic BALB and NZB mtDNA haplotypes in differentiated single ...

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Optogenetic stimulation inhibits the self-renewal of mouse embryonic stem cells

Optogenetic stimulation inhibits the self-renewal of mouse embryonic stem cells

... control)]. To determine whether reduced core TF activity after optical stimulation is involved in the compromised self-renewal, we examined the ability of ChR2-GFP-V6.5 ESCs to form colonies upon optical stimulation. ...

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Genome wide gene expression analysis in mouse embryonic stem cells

Genome wide gene expression analysis in mouse embryonic stem cells

... ABSTRACT Embryonic stem cell studies have generated great interest, due to their ability to form a wide variety of matured ...of embryonic stem cells (ESCs) and of the genes they ...

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The effect of mouse embryonic fibroblast in direct differentiation of mouse embryonic stem cells

The effect of mouse embryonic fibroblast in direct differentiation of mouse embryonic stem cells

... mES cells into derivatives of three germ layers is a dose response process, depending on factors that are released from MEF feeder cells into ES media in a coculture ...mES cells are induced to ...

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