Mouse Lung
Modeling metastasis biology and therapy in real time in the mouse lung
... the mouse lung micro- environment was assessed in real time for up to 21 ...and mouse cancer cell lines and the discrimination of tumor microenvironments in the lung that were most permissive ...
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Original Article The Effect of Different Doses of Cigarette Smoke in a Mouse Lung Tumor Model
... Abstract: Few studies have used Balb/c mice as an animal model for lung carcinogenesis. In this study, we investigated the effect of different doses of cigarette smoking in the urethane-induced Balb/c mouse ...
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Plasminogen activator inhibitor 1 in acute hyperoxic mouse lung injury
... Genetically deficient mice provide unique tools to discrimi- nate between causal and coincidental changes in gene expres- sion. Using mice made deficient in PAI-1 by gene targeting, we have demonstrated here that this ...
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Circular RNA profiles in mouse lung tissue induced by radon
... Histological assessment and immunohistochemistry H&E staining was conducted to examine histological pathology of lung tissue under a light microscope. Digital images were collected by a conventional light ...
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NLRP3 deletion inhibits inflammation-driven mouse lung tumorigenesis induced by benzo(a)pyrene and lipopolysaccharide
... to lung cancer induction by carcinogen and has a high incidence of spontaneous lung adenomas ...laboratory mouse and the most widely used mouse strain for use as models of human disease, has a ...
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Biodistribution of gold nanoparticles in mouse lung following intratracheal instillation
... The tissue selected for paraffin sectioning was dehydrated and paraffin embedded. The tissue was then cut into 8 μm thick sections. In all mice the same part of the liver was used for paraffin embedding, i.e., the right ...
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Measuring the lung function in the mouse: the challenge of size
... parenchymal lung mechanics. The airways constitute a large percentage of the lung in mice (11%) compared to rats ...the mouse trachea but is less well organized than in other species; only the upper ...
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The role of pleiotrophin and β-catenin in fetal lung development
... Fetal lung development is a complex biological process which involves temporal and spatial regulation of multi- ple factors such as growth factors, transcriptional factors, and extracellular matrix ...normal ...
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Comprehensive anatomic ontologies for lung development: A comparison of alveolar formation and maturation within mouse and human lung
... the mouse, review of existing human anatomic and developmental ontologies, such as FMA, UBERON, and the Human Developmental Anatomy Ontology ...man lung structures, especially those associated with the late ...
21
F0-containing noninfectious Sendai virus can initiate replication in mouse lungs but requires a relatively long incubation period.
... These results indicate that Sendai virus can initiate replication in the mouse lung even with the Fo-containing noninfectious virus and strongly suggest that this infection process is me[r] ...
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Proteomics of Bronchoalveolar Lavage Fluid Reveals a Lung Oxidative Stress Response in Murine Herpesvirus-68 Infection
... Analysis of bronchoalveolar lavage (BAL) fluid from MHV-68 infection of the mouse lung. 267[r] ...
27
Dispersion of single-walled carbon nanotubes by a natural lung surfactant for pulmonary in vitro and in vivo toxicity studies
... Human lung fibroblast CRL-1490 cells (ATCC, Mana- ssas, VA) or mice were treated with Survanta®, SWCNT, or control particles as described ...or mouse lung tissues were lysed and cell/tissue lysates ...
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Host predisposition by endogenous Transforming Growth Factor-β1 overexpression promotes pulmonary fibrosis following bleomycin injury
... in mouse lung. To probe the mechanism at work in the lung we determined and showed that the key components of TGFβ1 signalling were present in the lung, despite the lack of fibrotic ...
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Effect of aerosol particles generated by ultrasonic humidifiers on the lung in mouse
... the lung, suggesting that 7- and 14-day inhalation of the particles from the humidifier induced a cellular response from the alveolar macrophages but did not cause acute or sub-acute toxic effects on the ...
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Role of TNF-α in lung tight junction alteration in mouse model of acute lung inflammation
... the lung tissues col- lected from WT mice at 4 h and 24 h after carrageenan injection (Fig ...and lung tissues pro- duction of TNF-α were significantly reduced in carra- geenan-injected TNF-αR1KO mice as ...
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6110.pdf
... respectively. The conjugates of Greenwald et al. were designed to have an electron- withdrawing group in the α-position for effective hydrolysis [12, 13]. Although all three conjugates had similar in vitro cytotoxicity ...
160
Ajulemic acid exerts potent anti-fibrotic effect during the fibrogenic phase of bleomycin lung
... of lung fibrosis associated with some conditions (such as, desquamative interstitial pneumonia, bronchiolitis oblit- erans organizing pneumonia, BOOP, sarcoidosis ...of lung fibrosis and in particular of ...
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Inhibitory effects of Stemona tuberosa on lung inflammation in a subacute cigarette smoke induced mouse model
... In our research, we also investigated the changes in lymphocyte levels as well as those of macrophages and neutrophils because lymphocytes are another important factor in lung inflammation related to respiratory ...
12
Forced expiration measurements in mouse models of obstructive and restrictive lung diseases
... of lung function evaluations ...the lung, such as expiratory flow limita- tion, often play important roles in respiratory diseases and their evaluation should be, in our view, more frequently included in ...
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Anti-Fas mAb-induced apoptosis and cytolysis of airway tissue eosinophils aggravates rather than resolves established inflammation
... Apoptosis of eosinophil granulocytes is effectively induced in vitro by cross-linking of Fas membrane recep- tors with agonistic anti-Fas monoclonal antibody (mAb) [11,14,15]. Similarly, administration of anti-Fas mAb ...
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