Mouse mammary gland development
Neuropilin 2 promotes branching morphogenesis in the mouse mammary gland
... the mammary fat pad. (A) Schematic of method for quantification of mouse mammary gland ...whole-mounted mammary gland was divided into six areas by positioning their central ...
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PER2 regulation of mammary gland development
... during mouse mammary gland ...virgin mammary glands and undifferentiated mammary epithelial cells (MECs), whereas PER1 expression is highest in lactating mouse mammary ...
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PTEN overexpression suppresses proliferation and differentiation and enhances apoptosis of the mouse mammary epithelium
... during mouse mammary gland development, we generated MK-PTEN, a trans- genic mouse model in which human PTEN is overexpressed in ductal and alveolar mammary epitheli- um during ...
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A contrasting function for miR-137 in embryonic mammogenesis and adult breast carcinogenesis
... in mouse mammary gland development, we over-expressed miR-137 using a lentiviral system in the flank region of ...E11.0 mouse embryos and then cultured the flank for 72 ...
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Epithelial vimentin plays a functional role in mammary gland development
... the mammary gland, vimentin intermediate filaments are expressed in stromal cells and in basal epithelial cell populations, including gland- reconstituting mammary stem cells, with largely ...
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Diet-induced obesity impairs mammary development and lactogenesis in murine mammary gland
... of mouse ACC- ␣ (1, 3). Riboprobe vectors for mouse  -casein have been described previously ...for mouse ␣ -lactalbumin and whey acid protein (WAP) were prepared by PCR of lactating ...
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Key stages in mammary gland development: The mammary end bud as a motile organ
... the mammary stroma also caused accelerated ductal growth during puberty, confirming the stromal target for TGF- β ...factor. Mammary hepatocyte growth factor is negatively regulated by TGF- β and its ...
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Keratin 6 is not essential for mammary gland development
... and mouse, the mouse genes seem to have evolved after the species diverged ...The mouse isoforms, K6a and K6b, are organized in tandem on chromosome 15 and although their coding sequences show 95% ...
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Exosome signaling in mammary gland development and cancer
... Exosomes control metastatic spread whereby routes of com- munication between the primary tumor and metastatic sites are efficiently maintained. Breast cancer spreads primarily via the lymphatic system. Regional lymph ...
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Mouse models of mastitis – how physiological are they?
... the development of improved prevention and treatment strategies in both human and animal ...disease. Mouse models of mastitis involve administration of a mastitis-inducing agent to the mammary ...
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Key stages of mammary gland development: Molecular mechanisms involved in the formation of the embryonic mammary gland
... bulb-shaped mammary buds and occurs between ...dense mammary mesenchyme arrayed radially around the epithelial ...many mouse strains fetal androgens lead to the destruction of the mammary ...
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Atrazine and rat mammary gland development
... the development of CD-1 mouse mammary gland when exposed beginning on GD9 and continuing throughout the pregnancy (Markey et ...fetal mammary glands of rats and mice are sensitive to ...
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Homeobox genes in mammary gland development and neoplasia
... of mammary development and neoplastic ...in mammary gland develop- ment and neoplasia will be an exceptional ...the mammary gland has several advantages over many other ...
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Experimental manipulation of radiographic density in mouse mammary gland
... allow development of the pathophysiological changes that lead to mammary cancer in ...dense mammary glands may reveal differences in their sus- ceptibility to mammary tumor ...standardize ...
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Key stages in mammary gland development Secretory activation in the mammary gland: it's not just about milk protein synthesis!
... the mouse a single primary duct, which can be identified by its proximity to the nipple and the thick sheath of connective tissue, serves as a conduit for the passage of milk to the suckling ...post-pubertal ...
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Cx26 knockout predisposes the mammary gland to primary mammary tumors in a DMBA-induced mouse model of breast cancer
... rodent mammary gland also expresses Cx43 and Cx26 but also expresses Cx30 and Cx32 that are dynamically regulated throughout mammary gland development ...many mammary tumor cell ...
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NEW INSIGHTS OF MAMMARY GLAND DURING DIFFERENT STAGES OF DEVELOPMENT
... Mammary gland (modified sebaceous gland) is exocrine in nature and made up of branched network of ducts ending in alveoli ...This gland is an excellent system to study the molecular events ...
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Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model
... the mammary gland during puberty, pregnancy, and lactation is controlled by steroid and peptide hormones and growth ...to mammary tissue during late pregnancy and throughout ...on mammary ...
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A novel cell culture model for studying differentiation and apoptosis in the mouse mammary gland
... normal development and have proven to be a useful source of material to establish cell lines from tissues that have previously been refractory to culturing ...establish mammary epithelial lines from these ...
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Transforming growth factor β and breast cancer: Mammary gland development
... in mammary gland develop- ment soon after its ...functional development of the mammary gland is largely postnatal in both humans and mice (for review ...the mammary tree is ...
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