Mouse skin
ENHANCEMENT OF SKIN PERMEATION OF DILTIAZEM HYDROCHLORIDE GELS THROUGH MOUSE SKIN BY USING OLIVE OIL AS PERMEATION ENHANCERS
... olive oil in the concentrations range from 1% -2.5% were incorporated into the gels. The invitro skin permeation experiments are known for their value in studying the rate and mechanism of percutaneous absorption ...
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Identification of Glycoproteins from Mouse Skin Tumors and Plasma
... two-stage mouse skin carcino- genesis model has been used for decades to study the genetic, molecular, and biologic basis of tumor develop- ment ...two-stage skin tumor model has been used to improve ...
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Expression of naked DNA in human, pig, and mouse skin
... Quantitative assay for b -galactosidase activity. A chemiluminescence assay was used to quantitate the b -galactosidase activity in the epider- mis (12). Briefly, epidermal sheets were obtained 12 h after ex vivo injec- ...
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The Progression in the Mouse Skin Carcinogenesis Model Correlates With ERK1/2 Signaling
... the mouse skin model prompted us to examine the activation sta- tus of its downstream effector ...of mouse skin ...of mouse skin ...of mouse skin ...
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Detection of Cryptdin in Mouse Skin
... and mouse small ...BALB/c mouse skin by means of reverse transcriptase PCR ...the skin was found to be identical to that previously reported for ...the skin in embryonic and neonatal ...
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Inhibition of DMBA induced mouse skin carcinogenesis by Centella asiatica extract
... The results of the anticarcinogenicity study of Centella extract shows that Single topical application of DMBA followed by croton oil 2days/week for 16 week produced skin Papillomas which started appearing from 7 ...
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The Role of CDK6 and Cyclin D3 in Keratinocyte Proliferation and Mouse Skin Carcinogenesis.
... Figure 23. Kinetic of papilloma formation in K5CDK6/cyclin D3 ‐/‐ compound mice. Wild‐ type(wt), cyclin D3 ‐/‐ (D3 ‐/‐ ), K5CDK6 and K5CDK6/D1 ‐/‐ siblings were initiated with DMBA and promoted with multiple applications ...
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Enhanced Iontophoretic Delivery of Magnesium Ascorbyl 2 Phosphate and Sodium Fluorescein to Hairless and Hairy Mouse Skin
... 2.4. In Vivo Penetration of Sodium Fluorescein After euthanizing the 7-week-old female hairless SKH1 and the 5- or 7-week-old female hairy C57BL/6 mice with forane, the dorsal hairs were cut with an electric shaver. ...
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CCAAT/Enhancer Binding Protein Alpha in UVB Responses in Human and Mouse Skin and Mouse Skin Tumorigenesis
... human skin in vivo, biopsies from untreated and UVB-treated human skin (1 MED UVB) were collected from human volunteers (N=10) and examined for C/EBPα ...human skin revealed C/EBPα was extensively ...
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An Optogenetic Controllable T Cell System for Hepatocellular Carcinoma Immunotherapy
... The H&E staining of mouse skin demonstrated that no obvious skin dama- ges were observed under the long-term exposure to blue light (supplementary figure S11), suggesting the bio-[r] ...
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RNA isolation for transcriptomics of human and mouse small skin biopsies
... human skin biopsies, we tested the performance of our new protocol in a limited experiment with mouse skin bio- psies from test animals (un-)treated with UV light radia- tion (Additional file ...a ...
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Oil components modulate the skin delivery of 5-aminolevulinic acid and its ester prodrug from oil-in-water and water-in-oil nanoemulsions
... ALA skin perme- ation, this formulation was selected as a model emulsion for further in vivo ...nude mouse skin following in vivo topical application of ALA and mALA for 2, 4, and 8 ...
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GENETIC RELATIONSHIP BETWEEN ARYL HYDROCARBON HYDROXYLASE INDUCIBILITY AND CHEMICAL CARCINOGEN INDUCED SKIN ULCERATION IN MICE
... At least four types of observations support this view: inhibitors of aryl hydrocarbon hydroxylase, such as 7,8-benzoflavone, inhibit mouse skin tumorigenesis caused by repeate[r] ...
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In vitro cellular uptake of evodiamine and rutaecarpine using a microemulsion
... method. Mouse skin fibroblasts were cultured in vitro to investigate the optimal conditions for evodiamine and rutaecarpine uptake with different drug concentrations and administration ...
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Methyl-β-cyclodextrin up-regulates collagen I expression in chronologically-aged skin via its anti-caveolin-1 activity
... of mouse skin between 12- and ...in skin fibrosis [26]. Fortunately, MβCD is supposed not to induce skin fibrosis or fibrosis of major systemic organs of heart, lung, liver, and kidney from ...
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Topically applied ZnO nanoparticles suppress allergen induced skin inflammation but induce vigorous IgE production in the atopic dermatitis mouse model
... human skin have reported conflicting penetration results after epicutaneous exposure to ...healthy skin but also through tape-stripped and lesional skin ...human skin, variable amounts of ...
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Oxidative stress and dysfunctional NRF2 underlie pachyonychia congenita phenotypes
... Lowering GSH levels causes PPK-like alterations in WT mouse skin. To gauge the effect of enhanced oxidative stress alone on skin morphology, we next treated 1-month-old WT male mice through i.p. ...
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Identification of Bulge Stem Cells in Mouse and Human Hair Follicles
... of mouse whiskers and HF of mice and humans and were very useful in differentiating cell expression, revealing that the cells associated with CD34 and CD200 antibodies were differentially expressed in the ...
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Considerations for skin carcinogenesis experiments using inducible transgenic mouse models
... a mouse that lost more than 15% of body weight compared to wild-type lit- termates must be ...particular mouse model long enough to allow for conversion to malignant ...
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CD19 dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight skin mouse
... the skin and other visceral ...tight- skin (TSK) mouse is a genetic model for human ...TSK mouse was originally identified (4) as a spon- taneous mutation exhibiting increased synthesis and ...
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