mRNA expression profiles
Integrating transcriptome wide study and mRNA expression profiles yields novel insights into the biological mechanism of chondropathies
... There are two innovations in our study. First, given the common biological processes shared by different types of chondropathies, we conducted a TWAS using chondropathies as phenotypes. This approach may help us to ...
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Tissue specific mRNA expression profiles of GDF9, BMP15, and BMPR1B genes in prolific and non prolific goat breeds
... tissue-specific mRNA expression profiles of GDF9, BMP15, and BMPR1B genes in goats were ...The mRNA expression of the genes was detected in prolific Jining Grey goats and non-pro- lific ...
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Integrating microRNA and mRNA expression profiles of acute promyelocytic leukemia cells to explore the occurrence mechanisms of differentiation syndrome
... We identified 12 pairs of differentially expressed transcription factors/differentially expressed miRNAs, involving four differentially expressed transcription factors and eight differentially expressed miRNAs (Table 2). ...
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Integrating genome wide DNA methylation and mRNA expression profiles identified different molecular features between Kashin Beck disease and primary osteoarthritis
... The dataset of gene expression profiling for KBD and OA from our previous study was used here [7]. Briefly, KBD donors came from the KBD prevalent areas of Yongshou county and Linyou county of Xi’an city of the ...
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Assessing breast cancer cell lines as tumour models by comparison of mRNA expression profiles
... high expression in tumour ...using Expression data) paradigm stromal and immune ...Differential expression (box plot) and stromal correlations (scatterplot) are displayed for representative genes (b, ...
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lncRNA-mRNA expression profiles and functional networks of mesenchymal stromal cells involved in monocyte regulation
... Results: MSCs showed a strong ability to induce monocyte migration but inhibited monocyte differentiation into M1 macrophages. A total of 145 DE lncRNAs and 768 DE mRNAs were identified between the control and co-culture ...
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mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts
... Osteosarcoma is a heterogeneous tumor type, which can be subdivided into various subtypes[6]. Conven- tional high-grade osteosarcoma is the most common subtype, and can be further subdivided in different his- tological ...
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mRNA expression profiles for Escherichia coli ingested by normal and phagocyte oxidase deficient human neutrophils
... high expression ratios consequent to very low ...in expression, data are pre- sented in text and tables as “fold ...For expression ratios greater than one this value is simply the geomet- ric mean ...
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Original Article Identification of prognostic genes in paediatric medulloblastoma from mRNA expression profiles
... elevated expression level of NTRK3 (neurotrophic tyrosine kinase, receptor, type 3) indicated good prognosis [5-7], while the presence of high expression of CDK6 has been associated with poorer prognosis ...
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Effect of infliximab on mRNA expression profiles in synovial tissue of rheumatoid arthritis patients
... of expression in nonresponders before ...its expression was higher in good responders than in nonre- sponders before treatment, and was also found to be down- regulated in good responders following ...
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MicroRNA–mRNA expression profiles associated with medulloblastoma subgroup 4
... There were 867 miRNAs identified in at least a single MB sample; from those, 592 were identified across all samples. These originated from 687 precursors, of which 285 precur- sors had both the 5p and 3p strands ...
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Deregulated microRNA and mRNA expression profiles in the peripheral blood of patients with Marfan syndrome
... gene expression post-transcription- ally via sequence-specific interaction with the 3 ′ untrans- lated region (UTR) of a target gene’s mRNA, resulting in inhibition of translation and/or mRNA ...
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Computational analysis of mRNA expression profiles identifies a novel triple-biomarker model as prognostic predictor of stage II and III colorectal adenocarcinoma patients
... gene expression profile between primary cancer tissues and tissues from liver or lung metastatic sites as indicated in the flow chart of the study design (Figure ...
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Bioinformatic analysis of microRNA and mRNA Regulation in peripheral blood mononuclear cells of patients with chronic obstructive pulmonary disease
... sion profiles of PBMC in COPD ...miRNA expression may be linked to dysregulated mRNA expression relevant to the pathogenesis of ...and mRNA expression profiles in PBMCs ...
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Original Article Bioinformatics analysis of gene expression profile data to screen key genes involved in cardiac ischemia-reperfusion injury
... genome mRNA expression profiles in cardiac ischemia regions of rats with cardiac ischemia/reperfusion injury were analyzed to identify unique target ...
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Identification of miRNA mRNA crosstalk in CD4+ T cells during HIV 1 infection by integrating transcriptome analyses
... gene expression omnibus; miRNA: microRNA; LncRNA: long non-coding RNA; HDF: HIV dependency factors; PCAF: P300/CBP-associated factor; PBMC: peripheral blood mononuclear cell; DEM: differentially expressed miRNA; ...
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Distinct Severe Acute Respiratory Syndrome Coronavirus-Induced Acute Lung Injury Pathways in Two Different Nonhuman Primate Species
... cytokine expression, and it plays a role in the development of lung fibrosis (2, 9, ...ACE2 expression and thereby promotes lung injury ...gene expression, and lung ...
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Integrated miRNA-risk gene-pathway pair network analysis provides prognostic biomarkers for gastric cancer
... Notes: The X-axis refers to the pathways, and the Y-axis refers to the samples. The colors from green to red indicate the pathway expression level from low to high. Abbreviations: GABA, gamma-aminobutyric acid; ...
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Identification of Differentially Expressed Genes in Papillary Thyroid Cancers
... We adapted the ACP system for the identi- fication of DEGs involved in PTCs. Differential display was performed by using kits which incor- porated an ACP. We confirmed the expression patterns of 10 DEGs, and ...
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HIV-1 Nef-induced lncRNA AK006025 regulates CXCL9/10/11 cluster gene expression in astrocytes through interaction with CBP/P300
... gene expression in a paracrine ...the expression of HIV-1 genes are low, for example, HIV p24 in HIV-1 + postmortem brain astrocytes is rarely detected ...the expression of lncRNAs and ...IP-10 ...
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