MTHFR C677T
Association of methylenetetrahytrofolate reductase (MTHFR) C677T and A1298C polymorphisms with the susceptibility of childhood acute lymphoblastic leukaemia (ALL) in Chinese population
... the MTHFR C677T mutation could reduce the susceptibility to adult ALL, and their results suggested that the risk of ALL was reduced by ...the C677T mutation can reduce the risk of childhood ...the ...
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The Association of MTHFR C677T and A1298C Polymorphisms with Methotrexate Response and Toxicity in Psoriasis
... 29.1±13.8 and after treatment was 7.1±9.1. The genotype frequencies for MTHFR C677T in the remaining 86 cases were 70.9% (C/C), 26.8% (C/T), and 2.3% (T/T). Those for A1298C were 57.0% (A/A), 32.5% (A/C), ...
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MTHFR C677T and A1298C polymorphisms and lung cancer risk in a female Chinese population
... A total of 388 patients and 388 controls were included in the present study. All of the subjects were females. Mean ages of cases and controls (mean ± SD) were almost iden- tical (56.1 ± 12.0 and 56.1 ± 11.6 years, ...
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MTHFR ) C677T polymorphism with hyperuricemia. However, the results were controversial. We therefore con-
... the MTHFR C677T polymorphism with the risk of hyperuricemia ...the MTHFR 677T allele carriers had an increased hyperuricemia risk than the 677C allele carriers among elderly Japanese men ...the ...
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Association of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism with primary glaucoma in Saudi population
... The MTHFR C677T polymorphism influences homo- cysteine metabolism and hyperhomocysteinemia has been reported in glaucoma patients ...The MTHFR C677T polymorphism causes an alanine > valine ...
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Antiepileptic drug induced psychosis associated with MTHFR C677T: a case report
... in MTHFR. The allele frequencies of c.665C>T (also known as C677T), ...of MTHFR C677T with various diseases have been well ...The C677T allele frequency differs greatly among ethnic ...
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<em>MTHFR C677T</em> polymorphism and breast, ovarian cancer risk: a meta-analysis of 19,260 patients and 26,364 controls
... the MTHFR C677T mutation could significantly increase the breast cancer risk in both Caucasians and Asians (Table ...between MTHFR C677T polymorphism and ovarian cancer risk in Caucasians, ...
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Original Article Genetic polymorphism of MTHFR C677T contributes to the risk of ovarian cancer: a meta-analysis
... that MTHFR C677T polymorphism didn’t contribute to the risk of ovarian ...of MTHFR C677T and ovarian cancer risk in the Caucasian group, while MTHFR C677T polymorphism in the ...
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Analysis of the MTHFR C677T variant with migraine phenotypes
... the MTHFR C677T variant has been shown in several studies including a recent meta- analysis by Rubino et al [27] to confer a modest risk for MA ...the C677T variant and the clinical phenotypes of ...
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Association of Homozygous Thrombophilia Polymorphisms and Venous Thromboembolism in Shahrekord,Iran
... This study demonstrated that VTE was associated with a number of homozygous thrombophilic polymorphisms, and some of the known thrombophilic homozygous polymorphisms increased the risk of developing VTE, while others had ...
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Multiple Inherited Thrombophilic Gene Polymorphisms in Spontaneous Abortions in Turkish Population
... and MTHFR polymorphisms were found as not associated with recurrent pregnancy loss or pre- eclampsia ...between MTHFR C677T and unexplained recurrent pregnancy loss ...that MTHFR C677T ...
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Association of mthfr gene polymorphisms c677t and a1298c with coronary artery disease
... of MTHFR gene C677T and A1298C in the development of ...The MTHFR genotyping was performed based on polymerase chain reaction followed by restriction fragment length ...of MTHFR C677T ...
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Influence of Methylenetetrahydrofolate Reductase C677T Polymorphism on the Risk of Lung Cancer and the Clinical Response to Platinum Based Chemotherapy for Advanced Non Small Cell Lung Cancer: An Updated Meta Analysis
... the MTHFR C677T polymorphism showed a significant as- sociation with an increasing risk of NSCLC, except for the recessive model, and that no genetic model of the MTHFR C677T polymorphism was ...
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Association between Methylenetetrahydrofolate Reductase (MTHFR) Gene Polymorphisms and Susceptibility to Childhood Acute Lymphoblastic Leukemia in an Iranian Population
... of MTHFR gene polymorphisms on the risk of childhood ALL in a sample of the Iranian ...in MTHFR significantly decreased the risk of ALL in our ...the MTHFR C677T (rs1801133) variant and ALL ...
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Complex interaction between serum folate levels and genetic polymorphisms in folate pathway genes: biomarkers of prostate cancer aggressiveness
... For MTHFR C677T and MTHFR A1298C, the variant frequencies in Jamaican men were not significantly different from Afri- can-Americans (C/T ? T/T: ...of MTHFR C677T, but did not attain ...
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Predictive value of homocysteine for depression after acute coronary syndrome
... and MTHFR C677T polymorphism on depressive status and remission status, following analyses were carried out: i) homocysteine concentration was compared between genotypes using ANOVA, ii) associations ...
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Multidisciplinary approach and anesthetic management of a surgical cancer patient with methylene tetrahydrofolate reductase deficiency: a case report and review of the literature
... Our patient’s prior history was consistent with a hemostatic disorder. Before undergoing surgery for his cancer-related complaints, a complete screening for risk factors of thrombosis was performed. The levels of C and S ...
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Polymorphisms in methylenetetrahydrofolate reductase gene: Their impact on liver steatosis and fibrosis of chronic hepatitis c patients
... recipient MTHFR polymorphism in favouring graft fibrosis pro- gression in patients with recurrent HCV after orthotopic liver transplantation ...the MTHFR C677T polymorphism may play a role in ...
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Plasmatic higher levels of homocysteine in Non-alcoholic fatty liver disease (NAFLD)
... and MTHFR C677T and A1298C polymorphisms in Brazilian patients with ...for C677T and A1298C MTHFR polymorphisms using PCR-RFLP and PCR-ASA, respectively, and Hcy was determined by ...
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<p>Plausible relationship between homocysteine and obesity risk via <em>MTHFR</em> gene: a meta-analysis of 38,317 individuals implementing Mendelian randomization</p>
... MTHFR C677T was fi rst identi fi ed as a signi fi cant variant associated with obesity in a Thai ...that MTHFR 677T allele had an elevated obesity risk with a ...with MTHFR 677C allele in Indian ...
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