mucin secretion
Signaling Pathways in Airway Mucin Secretion: Roles of Protease-Activated Receptor-2, MARCKS, and Related Chaperone and Cytoskeletal Proteins.
... as mucin glycoproteins, defensins, kallikrein, antiprotineases, IgA, IgG, proteoglycans, lipids, lysozyme and lactoferrin ...function. Mucin glycoproteins are the major macromolecular components that ...
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Role of Protein Kinase C Delta in Airway Mucin Secretion
... airway mucin secretion: elastase, 7-9 cathepsin G, 10 and ...provoke secretion of mucin by isolated airway epithelial cells and glands from several ...HNE-induced mucin hypersecretion ...
141
Mir 21 Regulation of MARCKS Protein and Mucin Secretion in Airway Epithelial Cells
... airway mucin (the solid component of mucus) ...in mucin secretion, two separate airway epithelial cell lines, HBE1 (papilloma virus transformed) and NCI-H292 (mucodepidermoid derived) were utilized, ...
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Original Article Nucleus DJ-1/Park7 acts as a favorable prognostic factor and involves mucin secretion in invasive breast carcinoma in Chinese population
... Abstract: Background: DJ-1/Park7 is a cancer- and Parkinson’s disease-associated protein which has been impli- cated in various aspects of malignant transformation in human tumors. The aim of this study was to evaluate ...
10
Different Munc18 proteins mediate baseline and stimulated airway mucin secretion
... stimulated mucin secretion ...stimulated secretion, mucin production was first increased (mucous metaplasia) in all mutant mice using ovalbumin (OVA) sensitization and challenge to induce ...
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Uridine stimulate laxative effect in the loperamide-induced constipation of SD rats through regulation of the mAChRs signaling pathway and mucin secretion
... for mucin secretion and the expression of membrane water channel (aquaporine 8, AQP8) were increased significantly in the Lop + Urd treated group compared with Lop + Vehicle treated ...
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Functional Genomics of Mucin Secretion in the Airway Epithelium
... Mucin secretion, exocytosis of mucin granules, involves the translocation of the granule from the cytoplasm of the goblet cells to the plasma membrane where it docks and fuses thus secreting its ...
147
Calpain and miR-21 regulation of MARCKS protein and Mucin Secretion in Airway Epithelial Cells.
... the mucin secretory process, we then examined how expression of miR-21 and subsequent regulation of MARCKS expression could affect mucin ...airway mucin secretion, especially of MUC5AC, the ...
150
rccm.201706-1139oc.pdf
... and secretion of MUC5AC and MUC5B (Figures ...of mucin-secreting cells ...increased mucin production on a per cell basis (45, 46). The increased mucin gene transcription was also associated ...
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Entamoeba histolytica Induced Mucin Exocytosis Is Mediated by VAMP8 and Is Critical in Mucosal Innate Host Defense
... induced mucin exocytosis demonstrated a high dependency on kinases, specifically, protein kinase C (PKC), in facilitating mucin release in response to the mucosal pathogen Entamoeba histolytica ...with ...
14
Gefarnate stimulates mucin-like glycoprotein secretion in conjunctival tissue and ameliorates corneal epithelial damage in animal dry-eye models
... action of gefarnate on improving ocular surface damage is as follows. Gefarnate stimulates not only mucin secretion in the cornea and conjunctiva, but also stimulates the proliferation of goblet cells in ...
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Impact of Dietary Exogenous Enzyme Supplementation on Endogenous Secretion, Gastrointestianl Health, Nutrients Digestibility and Growth Performance of Poultry.
... the secretion of ...and mucin secretion, in relation to digestibility and nutrient ...enteric mucin secretion, which reduces endogenous nutrient loss and improves apparent nutrient ...
255
Original Article Collagenous micronodules in prostate cancer revisited: are they solely associated with Gleason pattern 3 adenocarcinomas?
... between mucin produc- ing tumor glands and CMs has also been reported by several authors [9, ...acid mucin secretion of prostate carcino- ma ...acid mucin by production of collagenase from ...
8
5’-adenosine monophosphate mediated cooling treatment enhances ΔF508-Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) stability in vivo
... The methods used were similar to those described by Best and Quinton [29]. In brief, mice were anaesthetized with isoflurane and maintained on a flat surface in a su- pine orientation with adhesive tape. The mouth was ...
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Original Article A case report of superficially spreading gastric cancer with distinct molecular features: a novel approach for evaluating gastric molecular carcinogenesis
... Abstract: A 62-year-old woman was admitted to our hospital because of epigastralgia. Upper gastrointestinal en- doscopy revealed a superficial spreading type of gastric tumor (superficially spreading gastric cancer, ...
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Healing Potential of Picrorhiza kurroa (Scrofulariaceae) rhizomes against indomethacin induced gastric ulceration: a mechanistic exploration
... The primary aim of this investigation was to study the healing property of the methanol extract of P. kurroa rhi- zome (designated as PK) against indomethacin-induced acute gastric ulceration of mice vis-à-vis that of ...
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Tracing Putative Trafficking of the Glycolytic Enzyme Enolase via SNARE-Driven Unconventional Secretion
... Detection of unconventional secretion of glycolytic enzymes. We performed 2D-HPLC-based cell surface proteome analysis to detect the extracellular presence of 11 glycolytic enzymes, namely, enolases (Eno1p and ...
8
Binding of Pseudomonas cepacia to normal human intestinal mucin and respiratory mucin from patients with cystic fibrosis
... As shown in microtiter binding assays, clinical isolates from 19/22 patients were found to bind to both mucins, with the highest specific binding exhibited by isolates from eight patient[r] ...
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Cholesterol Depletion in Cell Membranes of Human Airway Epithelial Cells Suppresses MUC5AC Gene Expression
... Purpose: If cholesterol in the cell membrane is depleted by treating cells with methyl-β-cyclodextrin (MβCD), the activities of transmembrane receptors are al- tered in a cell-specific and/or receptor-specific manner. ...
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Development of anti human colonic mucin monoclonal antibodies Characterization of multiple colonic mucin species
... radioimmunoassay to reflect the presence of identical epitopes on the different species. Adsorption of HCM species on a variety of affinity resins prepared with anti-HCM MAbs demonstrated that binding to multiple ...
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