Mucoadhesive polymer
DESIGN AND IN VITRO CHARACTERIZATION OF METADOXINE BUCCAL PATCHES USING BORASSUS FLABELLIFER FRUIT RESIN – A NOVEL MUCOADHESIVE POLYMER
... suitable polymer for developing a buccal drug delivery system with reasonably extended release of the ...a polymer combination of 3% w/v BFR and 5% w/v PVA seems to be an optimized formulation, since it ...
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FORMULATION AND EVALUATION OF ACYCLOVIR MATRIX TABLET USING MUCOADHESIVE POLYMER
... Mucoadhesive polymer owing to its binding capacity with gastric mucin prolongs the gastric residence time and thereby increases ...release mucoadhesive matrix tablet of ...
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Synthesis and evaluation of some novel thiomers as mucoadhesive polymer
... In order to evaluate this effect for the new polymers, water uptake studies were carried out with tablets based on the modified polymer. Thereby the obtained results are shown in Fig.7. As shown in Fig.6 the ...
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Design and In-Vitro Characterization of Metadoxine Buccal Patches using Borassus Flabellifer Fruit Resin - A Novel Mucoadhesive Polymer
... Buccal drug delivery is a newly adapted route of drug administration through the mucous membrane, lining the cheeks internally. Buccal drug delivery often involves a formulation which contains bio-adhesive or ...
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POLYMER IN MUCOADHESIVE MICROSPHERE DRUG DELIVERY SYSTEM-REVIEW
... a mucoadhesive polymer that will attach to related tissue or to the surface coating of the tissue for targeting various absorptive mucosa such as ocular, nasal, pulmonary, buccal, vaginal, ...called ...
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TRIGONELLA FOENUM GRAECUM L SEED MUCILAGE BASE MUCOADHESIVE MICROSPHERES OF DICLOFENAC SODIUM
... and mucoadhesive gelling agent 9 ...a mucoadhesive excipient in the formulation of the mucoadhesive polymer-based microsphere, and none of the studies used diclofenac sodium as the active ...
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Formulation development and in vitroevaluation of nizatidine microspheres
... the mucoadhesive polymer were dispersed in purified water (10 ml) to form a homogeneous polymer ...the polymer premix and mixed thoroughly with a stirrer to form a viscous ...
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Optimization of Transmucosal Buccal Delivery of Losartan Potassium using Factorial Design
... that mucoadhesive films of losartan potassium gives better therapeutic efficiency by con- trolling drug release and it may increase bioavailability leading to decreased dosing and fewer side ...percentage ...
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Formulation and invitro Characterisation of Mucoadhesive Microspheres of Oseltamivir by Ionic Gelation Method
... Oseltamivir microspheres were prepared successfully using sodium alginate, Hydroxy propyl methyl cellulose, Carboxy methyl cellulose and Carbopol as a mucoadhesive polymer in different proportions by using ...
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“DEVELOPMENT OF CHITOSAN BASED BIOADHESIVE BILAYERED PATCHES OF METOPROLOL TARTARATE” Sharon Furtado*, Srinivasan Bharath, Basappa Veerbadraiah Basavaraj, Sindhu Abraham, Rajamanickam Deveswaran, Varadharajan Madhavan, India.
... containing mucoadhesive buccal patches to ensure satisfactory unidirectional release of metoprolol ...tartarate. Mucoadhesive bilayered buccal patches of metoprolol tartarate were formulated using chitosan ...
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FORMULATION AND EVALUATION OF IN-SITU NASAL GEL OF SALBUTAMOL SULPHATE
... adrenoreceptor agonist and rapidly absorbed from gastro intestinal tract but it is subjected to first pass metabolism. Thus oral bioavailability is only 50%. Hence, an In situ nasal gel of Salbutamol Sulphate was ...
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Formulation and Evaluation of Buccoadhesive Drug Delivery System for Lovastatin
... Lovastatin, a hyperlipedemic agent used in the treatment of hypercholesterolemia, has poor bioavailability ( less than 5%) due to the first pass metabolism and thus the dosing frequency is more, as a result of which ...
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Formulation and Evaluation of Glucosamine Sulphate Transdermal
... ABSTRACT: The purpose was to develop transdermal delivery systems (TDS) of Glucosamine Sulphate using Pluronic F-127 (PF-127) and mucoadhesive polymer sodium carboxymethylcellulose (Na CMC) in order to ...
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A Review on Mucoadhesive Drug Delivery System
... bioadhesive polymer and the biological tissue due to proper wetting of the bioadhesive surface and swelling of the ...the mucoadhesive polymer chains and those of the ...the polymer plays a ...
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Formulation and Evaluation of Mucoadhesive Buccal Tablets by using Central Composite Design for Anti Hypertensive Drug Losartan Potassium
... a polymer not only depends on its molecular properties, but also on the environmental factors adjacent to the ...the mucoadhesive polymer can alter the ionization state and, therefore, the adhesion ...
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FORMULATION AND CHARACTERIZATION OF MUCOADHESIVE MICROPARTICULATE DRUG DELIVERY SYSTEM ENCAPSULATED WITH SILYMARIN
... Thus, mucoadhesive dosage forms are advantageous in increasing the drug plasma concentrations and also therapeutic ...into mucoadhesive drug delivery ...formulate mucoadhesive microspheres of ...
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In situ gel for nasal drug delivery
... a mucoadhesive in situ nasal gel with modulated rheological and mucociliary transport ...gelling polymer poloxamer 407, different mucoadhesive polymers (chitosan, hydroxypropyl cellulose, carbopol ...
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Formulation & evaluation of muccoadhesive buccal patches for delivery of atenolol
... technique. Mucoadhesive polymer, namely sodium carboxymethyl cellulose (NaCMC) of different grade were incorporated into the patches to modify their mucoadhesive properties as well as the rate of ...
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“BUCCAL PATCH: A TECHNICAL NOTE” Harshad G. Parmar*, Janak J. Jain, Tarun K. Patel, Vishnu M. Patel, India.
... more polymer films or layers containing the drug and/or other ...a mucoadhesive polymer layer which bonds to the oral mucosa, gingiva, or teeth for controlled release of the drug into the oral mucosa ...
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EFFECT OF MAGNESIUM STEARATE ON MUCOADHESIVE MICROSPHERES OF REPAGLINIDE
... a Mucoadhesive polymer dispersed inside the ...evaluate mucoadhesive microspheres of repaglinide employing mucoadhesive polymers for prolonged gastro- intestinal ...The mucoadhesive ...
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