Mucus production
SPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus production
... of mucus production, includ- ing protein glycosylation and mucin secretion, as well as genes that are highly represented in experiments in which mice were exposed to pulmonary allergens or ...with ...
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IL 13–induced airway mucus production is attenuated by MAPK13 inhibition
... Design and validation of MAPK13 inhibitors. Taken together, our results in human cells and lungs pointed to a central role for MAPK13 in regulating airway mucus production and there- fore suggested the ...
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Niclosamide repurposed for the treatment of inflammatory airway disease
... intracellular mucus as well as airway contraction (Figure 1, ...abolished mucus production. Thus, there was no intracellular mucus left to be released by ...for mucus production ...
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C5 Modulates Airway Hyperreactivity and Pulmonary Eosinophilia during Enhanced Respiratory Syncytial Virus Disease by Decreasing C3a Receptor Expression
... and mucus production can be seen in ERD when C3aR is overexpressed (as in B10D2 C5 ⫺/⫺ ...eosinophilia, mucus production, and airway ...
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Anti-inflammatory effects of Salvia plebeia R. Br extract in vitro and in ovalbumin-induced mouse model
... inhibited production of pro‑inflammatory cytokines, such as TNF‑α and IL‑6, as well as nitric oxide (NO) in LPS‑stimulated RAW ...cytokine production was suppressed more effectively by SE of the aerial ...
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Deguelin Attenuates Allergic Airway Inflammation via Inhibition of NF-κb Pathway in Mice
... and mucus production, suppressed airway hyperresponsiveness, and inhibited serum immunoglobulin and Th2 cytokine levels in a dose-dependent manner in asthmatic ...
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Exposure of neonates to Respiratory Syncytial Virus is critical in determining subsequent airway response in adults
... inflammation, mucus hyperproduction, and colla- gen deposition in the subepithelial reticular layer of the airway were observed in mice exposed to RSV and/or Ova (Figure 5A: inflammation; Figure 5B: mucus ...
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Using the mucosal response to recombinant Neoparamoeba perurans attachment proteins to design an experimental vaccine against amoebic gill disease (AGD)
... by mucus, which forms a thin interface between the organism and ...excessive mucus production in the ...skin mucus samples were obtained from Atlantic salmon (Salmo salar) which were infected ...
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Mucus Glycoproteins Selectively Secreted from Bacteriocytes in Gill Filaments of the Deep Sea Clam Calyptogena okutanii
... viscoelastic mucus from the gill, which is thought to be a physical and chemical ...The mucus collected from the gill was shown to be composed of glycoproteins having the follow- ing sugar composition: Man ...
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Modelling and Simulation of Biological Regulatory Networks by Stochastic Petri Nets
... the mucus production in Pseudomonas Aeruginosa BRN and results given by the Stochastic Petri Nets are in agreement with the Hybrid Modeling results from which establishes the accuracy of this approach as ...
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Pandemic Swine H1N1 Influenza Viruses with Almost Undetectable Neuraminidase Activity Are Not Transmitted via Aerosols in Ferrets and Are Inhibited by Human Mucus but Not Swine Mucus
... of mucus does not impact the interaction of mucus with WGA (21, ...whether mucus production decreased due to declin- ing cell health caused by viral ...and mucus content overall (data ...
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Altered mucosal immune response after acute lung injury in a murine model of Ataxia Telangiectasia
... One week after mucosal injury Atm − / − mice showed hyperemic lung tissue (Figure 5e) and increased mucus production (Figure 5g) in comparison to control mice (Figure 5f and h).. ATM def[r] ...
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Depression Among Pregnant Latinas In South Carolina
... The mucus layer tends to thickness with increased diversity of the microbiota (Jakobsson, et ...the mucus layer provides a source of nutritional carbon and therefore energy to some of the intestinal flora ...
199
Respiratory syncytial virus infection of newborn CX3CR1-deficient mice induces a pathogenic pulmonary innate immune response
... of mucus-producing genes showed a significant decrease in the expression of Muc5ac and Gob5 mRNA in pups treated with αIL-17RC compared with that in pups treated with IgG control antibody (Figure ...ed ...
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Increased human Ca2+-activated Cl-channel 1 expression and mucus overproduction in airway epithelia of smokers and chronic obstructive pulmonary disease patients
... In this study, we identified that cigarette smoking was implicated in the pathophysiology of COPD by inducing mucus overproduction via CLCA1 expression. However, the mechanism by which smoking induces CLCA1 ex- ...
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12501.full.pdf
... cilial-dependent mucus clearance, ...of mucus biophysical properties on cough efficacy. Theoretically, mucus can be cleared by cough from the lung by an adhesive failure, ...breaking ...
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Pulmonary expression of interleukin 13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
... Production and identification of transgenic mice. To study the res- piratory effector functions of IL-13, we took advantage of the high density of Clara cells in the murine respiratory epitheli- um (50, 51) and ...
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Place des tests d’interaction sperme-mucus dans le bilan masculin de l’infécondité
... Comparison of the in vitro sperm penetration test using human cervical mucus and bovine estrus cervical mucus with the postcoital test.. Sterility in the male and female a[r] ...
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Interaction Between Chitosan and Mucin: Fundamentals and Applications
... Chitin is one of the most abundant polysaccharides in nature, with an estimated annual production of 10 to 100 trillion of metric tons [23,24]. Chitin can be found in the exoskeleton of arthropods, in the fungus ...
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Mucocele: A Case Report with Etiopathogenesis, Clinical Features and Various Treatment Options
... A mucocele is a benign, mucous-containing cystic lesion of the minor salivary glands presenting as a distinct, fluctuant, painless swelling of the mucosa. Mucocele is a clinical term used that includes mucous ...
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