• No results found

muscle atrophy

Original Article IL-6 improves myogenesis in long-term skeletal muscle atrophy via the JAK/STAT3 signalling pathway

Original Article IL-6 improves myogenesis in long-term skeletal muscle atrophy via the JAK/STAT3 signalling pathway

... Muscle atrophy is a common clinical problem that is often associated with three conditions: chronic diseases (cachexia), disuse conditions (atrophy), and aging (sarcopenia) ...[1]. Muscle ...

12

Transcriptional profiling to identify therapeutic targets influencing skeletal muscle atrophy

Transcriptional profiling to identify therapeutic targets influencing skeletal muscle atrophy

... qRT-PCR validation for the transcripts of other genes of interest did however reflect the changes seen in microarray analysis. Myog transcript levels were observed to increase markedly following nerve block, with a ...

220

FGFR1 inhibits skeletal muscle atrophy associated with hindlimb suspension

FGFR1 inhibits skeletal muscle atrophy associated with hindlimb suspension

... skeletal muscle fibers in ...suspended muscle as compared to muscles isolated from weight bearing control ...in muscle undergoing hind limb sus- pension induced-atrophy ...

12

MST1, a key player, in enhancing fast skeletal muscle atrophy

MST1, a key player, in enhancing fast skeletal muscle atrophy

... induced muscle atrophy, mice were anesthetized, the scia- tic nerve of left hind limb was exposed by blunt dissection and a 3 mm piece was ...control. Muscle samples were har- vested at 3, 7, 10 and ...

13

Original Article MURF contributes to skeletal muscle atrophy through suppressing autophagy

Original Article MURF contributes to skeletal muscle atrophy through suppressing autophagy

... Introduction: Muscle atrophy due to denervation, immobilization, or unweighting inflicts large number of patients, and provides a huge challenge to modern ...in atrophy muscle, while how ...

5

Clinical findings and outcome of dogs with unilateral masticatory muscle atrophy

Clinical findings and outcome of dogs with unilateral masticatory muscle atrophy

... tests were performed at the time of euthanasia. This dog may have developed neurological signs because of trigeminal nerve pathology, but it also is possible that this dog could have developed an unrelated neurological ...

8

Pathways of Skeletal Muscle Atrophy: HIV as a Model System?

Pathways of Skeletal Muscle Atrophy: HIV as a Model System?

... It is unknown how TNF activates NF_B, although it may go through the aforementioned IKK pathway. It is known that TNF causes the increase in the level of MURF1 and decreases the level of MyoD mRNA, causing skeletal ...

7

Anesthetic management of spinal muscle atrophy type II in a parturient

Anesthetic management of spinal muscle atrophy type II in a parturient

... trafficking in axons. SMA is thought to result from insufficient levels of SMN protein in spinal anterior motor neurons. Absence of the gene SMN1 leads to atrophy and death of spinal anterior motor neurons. A ...

6

Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice

Acylated and unacylated ghrelin impair skeletal muscle atrophy in mice

... asone-induced atrophy and atrogene ...skeletal muscle, but also showed the spe- cific contribution of the mTORC2- over the mTORC1-mediated signaling pathway, which may explain, at least in part, the ability ...

13

Pharmacological inhibition of GSK-3 in a guinea pig model of LPS-induced pulmonary inflammation: II. Effects on skeletal muscle atrophy

Pharmacological inhibition of GSK-3 in a guinea pig model of LPS-induced pulmonary inflammation: II. Effects on skeletal muscle atrophy

... In view of the significance of GSK-3 signaling in the processes that determine muscle mass [40,65], markers of protein synthesis and degradation were assessed in muscle homogenates. As indicated earlier, ...

15

Deletion of Nlrp3 protects from inflammation-induced skeletal muscle atrophy

Deletion of Nlrp3 protects from inflammation-induced skeletal muscle atrophy

... skeletal muscle [4, ...of muscle atrophy [1, 4, 10 – 13]. The E3 ligase, muscle RING finger (MuRF) 1 (TRIM63), and F-box protein atrogin 1 (FBXO32) are increased in muscle during ...

15

MYONUCLEI ARE NOT LOST DURING MUSCLE ATROPHY

MYONUCLEI ARE NOT LOST DURING MUSCLE ATROPHY

... DURING MUSCLE ATROPHY We have all experienced the fact that skeletal muscles can change ...Such muscle shrinkage is termed disuse atrophy and, currently, the only way to build the ...

5

Transcription Factors in Muscle Atrophy Caused by Blocked Neuromuscular Transmission and Muscle Unloading In Rats

Transcription Factors in Muscle Atrophy Caused by Blocked Neuromuscular Transmission and Muscle Unloading In Rats

... In muscle tissue, low doses have been re- ported to promote myogenesis and my- otube formation, whereas high doses have an opposing effect via activation of the transcription factors in the NFκB- family and an ...

10

Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy

Intermittent glucocorticoid steroid dosing enhances muscle repair without eliciting muscle atrophy

... acute muscle injury and in muscular dystrophy and determined that both regimens provided comparable benefits in terms of annexin gene expression and muscle ...improved muscle function and ...

16

Habitual Exercise Attenuates the Aging Associated Muscle Atrophy and Muscle Strength Decline in SAMP8

Habitual Exercise Attenuates the Aging Associated Muscle Atrophy and Muscle Strength Decline in SAMP8

... reduces muscle protein synthesis [11]. Akt is one of the muscle protein synthesis related protein, and is upstream protein of muscle protein ...activates muscle protein ...the muscle ...

10

Hormonal control of muscle atrophy and degeneration in the moth Antheraea polyphemus

Hormonal control of muscle atrophy and degeneration in the moth Antheraea polyphemus

... In intact insects, the appearance of EH on the next day resulted in the rapid degeneration of the muscles, but if the abdomens were isolated prior to peptide release, the muscles simply [r] ...

20

Muscle memory and a new cellular model for muscle atrophy and hypertrophy

Muscle memory and a new cellular model for muscle atrophy and hypertrophy

... during atrophy and ...of muscle mass, which is illustrated in ...from muscle stem cells residing inside the fibre basal lamina (hence called satellite cells), resulting in a large fibre with many ...

8

Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia

Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia

... TA muscle samples being homogenized in relax buffer (90 mmol/L HEPES, 126 mmol/L KCl, 36 mmol/L NaCl, 1 mmol/L MgCl, 50 mmol/L EGTA, 8 mmol/L ATP, 10 mmol/L creatine phosphate; pH ...fraction, muscle ...

15

Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype

Neuron specific reduction in CuZnSOD is not sufficient to initiate a full sarcopenia phenotype

... on muscle mass and ...significant muscle atrophy in a number of ...gastrocnemius muscle, a muscle that undergoes a significant loss of mass during aging (Muller et ...that muscle ...

31

Muscle performance and ankle joint mobility in long term patients with diabetes

Muscle performance and ankle joint mobility in long term patients with diabetes

... in muscle performance, as it was for long-term, non neuropathic ...of muscle performance in the other two planes of the ana- tomical reference system showed that moments of force were significantly reduced ...

8

Show all 10000 documents...

Related subjects