muscle-specific gene expression
In vivo analysis of two striated muscle actin promoters reveals combinations of multiple regulatory modules required for skeletal and cardiac muscle specific gene expression
... mammalian muscle actin genes, and some of them have been confirmed to upregulate actin transcrip- tion when bound by myogenic determination factors such as MyoD (Sartorelli et ...actin gene, combinations of ...
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A novel tetracycline-responsive transgenic mouse strain for skeletal muscle-specific gene expression
... skeletal muscle α-actin (HSA) gene was amplified from human genomic DNA (Promega, Madison, WI, USA) and cloned into the ClaI site of the SG5 expression vector (Agilent Technologies, Santa Clara, CA, ...
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Ceasing of muscle function with aging: is it the consequence of intrinsic muscle degeneration or a secondary effect of neuronal impairments?
... skeletal muscle intimately depends on the central and peripheral nervous ...control muscle contraction through the well-characterised process of excitation–contraction coupling; in addition, motor neurons ...
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Gene recombination in postmitotic cells Targeted expression of Cre recombinase provokes cardiac restricted, site specific rearrangement in adult ventricular muscle in vivo
... test specific hypotheses regarding the role of TGF b 1 in adult disease is impeded by the animals’ mul- tifocal immunological disorders, poor viability, and absolute requirement for an immunodeficient background; ...
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Transcriptional Enhancer Activity of Biochemically Marked Genomic Elements
... the muscle and erythroid lineage (Tal1 and MRFs, both of which recognize the Ebox) resulted in a similarly low overlap of ...non-native gene expression in non-homologous cell ...
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Myostatin genotype regulates muscle specific miRNA expression in mouse pectoralis muscle
... miRNA expression observed in the absence of functional Myostatin could be the result of enhanced Myf5 and MEF2A gene ...MEF2A gene expression ...over expression of Myf5 was capable of ...
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Gene Expression Profiling of Skeletal Muscle of Nursing Piglets
... duced expression in the soleus muscle of hindlimb suspended mice ...numerous muscle-specific genes, and are expressed only in de- veloping muscle with MEF2A and MEF2C being spe- cific ...
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The role of Drosophila Lamin C in muscle function and gene expression
... Larval muscle-specific expression of wild type Drosophila Lamin C caused no overt ...larval muscle-specific expression of a truncated form of Lamin C lacking the N-terminal head ...
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Appropriate in vivo expression of a muscle-specific promoter by using avian retroviral vectors for gene transfer [corrected]
... To investigate the behavior of cellular promoters that have been introduced into the avian retroviral vectors, we linked the CAT gene to the chicken ask-actin or the P-actin promoter and[r] ...
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CArG elements control smooth muscle subtype–specific expression of smooth muscle myosin in vivo
... smooth muscle myosin heavy chain (SM-MHC) is tightly controlled depending on the differentiated state of smooth muscle cells ...SM-MHC gene in vivo, we tested the function of several conserved CArG ...
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Alveolar rhabdomyosarcoma – The molecular drivers of PAX3/7-FOXO1-induced tumorigenesis
... PAX3 expression occurs in the neural tube and dermomyotome [23], and it is required for the normal migration of skeletal muscle precursors to the limb bud ...PAX7 expression is a marker of satellite ...
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Skeletal muscle gene expression in response to resistance exercise: sex specific regulation
... of gene transcriptional ...in muscle phenotypes is greater for upper as compared to lower limb muscula- ture[1]; 2) lifestyle influences on upper body are rela- tively small since lower body musculature ...
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Enhancing myogenic differentiation of pluripotent stem cells with small molecule inducers
... the expression of mesoderm factors Meox1 and Pax3 ...Pax3 gene expression than bexarotene ...temporal expression of muscle-specific gene program in bexarotene-enhanced P19 ...
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TGFβ and FGF promote tendon progenitor fate and act downstream of muscle contraction to regulate tendon differentiation during chick limb development
... Col1a1 expression is downregulated in tendons of Scx −/− mutant mice (Murchison et ...Col1a1 gene by Scx, via direct binding on the Col1a1 promoter (Lejard et ...Col14a1 expression is lost in ...
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Muscle specific overexpression of AdipoR1 or AdipoR2 gives rise to common and discrete local effects whilst AdipoR2 promotes additional systemic effects
... primers specific for human AdipoR2 to rule out the possibility that these effects may reflect leaky expression of AdipoR2 in tissues other than the test ...AdipoR2 expression (data not shown) leaving ...
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Site-specific gene expression patterns in oral cancer
... The expression of 17 genes involved in cell cycle and growth control (p16, p21, p27, p53, cyclin D1, EGFR, c-kit, bcl-6), cell adhesion (alpha-, beta-, and gamma-catenin), and apoptosis/stress response genes ...
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The Evolution of X-Linked Genomic Imprinting
... of gene expression in females, this results in higher expression from m, the (Iwasa et ...major gene model (Ander- easily be explained by the conflict hypothesis (Iwasa son and Spencer ...
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Muscle specific expression of IGF 1 blocks angiotensin II–induced skeletal muscle wasting
... soleus muscle from angiotensin II–infused mice at 7 days weighed less than those from pair-fed, sham-infused controls (Figure 1, C and ...gastrocnemius muscle (P < ...the muscle of angiotensin ...
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Muscle Research and Gene Ontology: New standards for improved data integration
... skeletal muscle regeneration and satellite cell compartment self renewal involved in skeletal mus- cle ...to muscle growth and adaptation [17]. Skeletal muscle is capable of complete regeneration due ...
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No effect of 25-hydroxyvitamin D supplementation on the skeletal muscle transcriptome in vitamin D deficient frail older adults
... Results: Expression of the vitamin D receptor gene was virtually undetectable in human skeletal muscle biopsies, with Ct values exceeding 30. Blood 25-hydroxycholecalciferol levels were significantly ...
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