Mutant lines
Article: Morphological characterization of NERICA mutant lines and their parents
... of mutant lines from different species have been isolated and successfully used in many different areas of plant biology and crop breeding (Fu et ...2700 mutant varieties, that have been released ...
15
Performance of sorghum mutant lines for yield and quality of fodder under Udaipur conditions
... of mutant lines under the Udaipur conditions and identification of suitable mutant line for growing under such conditions and even some of the mutant lines may be used in the breeding ...
7
EVALUATION OF WHEAT MUTANT LINES FOR YIELD AND YIELD COMPONENTS UNDER DIFFERENT SOWING DATES
... fourteen mutant lines compete it under normal sowing, while it gave ...four mutant entries. Thirteen mutant lines performed better under normal and late sown trial as compared to short ...
12
The Dominance of the Herbicide Resistance Cost in Several Arabidopsis thaliana Mutant Lines
... borg et al. 2002), the high selfing rate may temporarily were measured during the experiment: germination date create and maintain large linkage groups through the (time from sowing to cotyledon emergence), rosette ...
12
High throughput phenotyping for aphid resistance in large plant collections
... Because TuYV does not show any symptoms on A. thaliana, we conducted DAS-ELISA to detect the virus in plants. Two weeks post infestation with TuYV- viruliferous aphids two samples of newly developed leaves (approximately ...
7
The DNA damage checkpoint kinase ATM regulates germination and maintains genome stability in seeds
... atm mutant seed is due to loss of the checkpoint activity that slows germination in the presence of DNA ...atm mutant seed than in Col-0 or atr lines ...type lines, coinciding with a loss in ...
36
Exploiting high-throughput cell line drug screening studies to identify candidate therapeutic agents in head and neck cancer
... Cell lines are not perfect models of cancer due to their lack of three-dimensional stromal environment, lack of interactions with an immune system, and an inability to test drug delivery ...cell lines and ...
10
Glutathione transport: a new role for PfCRT in chloroquine resistance.
... parasite lines carrying wild-type or mutant pfcrt, we reveal lower levels of GSH in the mutant lines and enhanced sensitivity to the GSH synthesis inhibitor l -buthionine sulfoximine, without ...
13
Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish
... gas6 mutant founders from five fish screened ...different mutant alleles (Additional file 9: Data S1) where each allele carried a different four nucleo- tide deletion, but translation of each mutant ...
24
Lose-of-Function of a Rice Nucleolus-Localized Pentatricopeptide Repeat Protein Is Responsible for the floury endosperm14 Mutant Phenotypes
... The lines indicate 5 ′ -UTR and 3 ′ - UTR, ...of mutant gene leads to a premature stop ...flo14 mutant (flo14) and three flo14 mutant lines expressing the wild-type OsNPPR3 gene (Com1, ...
15
High-throughput direct regeneration of soybean mutant and common lines from cotyledonary node
... soybean mutant line were utilized in these experiments. Mutant line obtained from Agricultural, Medical and Industrial Research School, Nuclear Science and Technology Research Institute, Atomic Energy ...
9
Canine parvovirus host range is determined by the specific conformation of an additional region of the capsid.
... cell lines. Although both cell lines were resistant to FPV and susceptible to CPV-d, they differed in susceptibility to different ...three mutant viruses with Ala-300 replaced by Asp were able to ...
9
DNA double strand break repair enzymes function at multiple steps in retroviral infection
... the mutant cell lines were reported to be only hypomorphic, the effects of their deficiencies are likely limited in this study ...cell lines compared to the control cell lines indicates the ...
13
Vemurafenib resistance reprograms melanoma cells towards glutamine dependence
... Since in vitro data demonstrated the potential of glu- taminase inhibitors to treat resistant cell lines, we asked whether these inhibitors would also be effective in vivo. To do this, xenograft experiments with ...
11
CDK1 Is a Synthetic Lethal Target for KRAS Mutant Tumours.
... p.G12V mutant cell lines after AZD5438 ...p.G12V mutant cells showed a decrease in S and G2-fractions after exposure to AZD5438 when compared to control (DMSO) treated cells and to KRAS WT cells ...
22
Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression
... from normal somatic cells need to reactivate TERT(10). The mech- anism of TERT promoter reactivation is not clearly understood. RAS, MYC, β-catenin, NF-κB, and several other transcription factors have been proposed to ...
17
Characterisation of CIP29:a potential target of the eukaryotic DNA damage response
... CIP29 mutant cell line implicates CIP29 in the highly regulated cytokinesis ...C9 mutant cells, CIP29 expression was shown to be completely abolished, whereas in the CIP29 siRNA knockdown cells, CIP29 ...
88
Inherited Methylmalonyl CoA Mutase Apoenzyme Deficiency in Human Fibroblasts: EVIDENCE FOR ALLELIC HETEROGENEITY, GENETIC COMPOUNDS, AND CODOMINANT EXPRESSION
... The mutant cell lines fall into two ...The mutant enzyme in the mut − mutants exhibits a 50- to 5,000-fold elevated Michaelis constant (K m ) for adenosylcobalamin in vitro, a normal K m for ...
10
Synthesis of stress proteins is increased in individuals with homozygous PiZZ alpha 1 antitrypsin deficiency and liver disease
... Several lines of evidence suggest that the stress response is related to the intracellular accumulation of the mutant a,-AT protein: there is a reduction in plasma concentrations of al-A[r] ...
8
A recombinant chimeric protein specifically induces mutant KRAS degradation and potently inhibits pancreatic tumor growth
... as molecular switches that cycle between the GDP-bound inactive and the GTP-bound active forms [10]. When bound to GTP, they interact with the downstream protein Raf and transduce the signal to activate various cell ...
11