Mycobacterium tuberculosis (Mtb)
Detection of Mycobacterium tuberculosis in Blood by Use of the Xpert MTB/RIF Assay
... sensitive Mycobacterium tuberculosis detection in large volumes of blood with the Xpert MTB/RIF ...M. tuberculosis surrogate ...Xpert MTB/RIF ...Xpert MTB/RIF test, enabling up ...
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Evaluation of Cobas TaqMan MTB for Direct Detection of the Mycobacterium tuberculosis Complex in Comparison with Cobas Amplicor MTB
... of Mycobacterium tuberculosis complex DNA from clinical specimens has become an important part of diagnostic ...M. tuberculosis complex DNA detection is dependent on the patient’s clinical data and ...
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Evaluation of the Xpert® MTB/RIF assay and microscopy for the diagnosis of Mycobacterium tuberculosis in Namibia
... Background: Tuberculosis (TB) kills approximately two million people and infects around nine million worldwide ...Xpert® MTB/RIF assay is a promising innovation for diagnosing TB and detecting resistance to ...
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Moxifloxacin resistance in the F15/LAM4/KZN extensively drug-resistant strain of <em>Mycobacterium tuberculosis</em>
... the tuberculosis (TB) epidemic by creating a population of immunosuppressed individuals that are highly susceptible to Mycobacterium tuberculosis (MTB) ...of MTB is of vital importance ...
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<p>Distribution and Frequency of <em>rpo</em>B Mutations Detected by Xpert MTB/RIF Assay Among Beijing and Non-Beijing Rifampicin Resistant <em>Mycobacterium tuberculosis</em> Isolates in Bangladesh</p>
... Xpert MTB/RIF (Xpert) assay and the Line Probe Assay (LPA) can simultaneously detect Mycobacterium tuberculosis complex (MTBC) and drug resistance in both pulmonary and extra-pulmonary ...
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Reverse docking study unravels the potential Mycobacterium tuberculosis enzyme targets of Agelasine F
... against Mycobacterium tuberculosis has been successfully docked to several druggable Mtb enzyme targets, namely, enoyl reductase (InhA), Isoniazid-resistant I21V and S94A enoyl-ACP (COA) reductase ...
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Genetic diversity and molecular epidemiology of multidrug resistant Mycobacterium tuberculosis in Minas Gerais State, Brazil
... Abbreviations MTb: Mycobacterium tuberculosis; MDR: Multidrug-resistant; TB: Tuberculosis; HGDI: Hunter-Gaston discriminatory index; LAM: Latin-American Mediterranean; U: Unknown profile[r] ...
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The New Xpert MTB/RIF Ultra: Improving Detection of Mycobacterium tuberculosis and Resistance to Rifampin in an Assay Suitable for Point of Care Testing
... Xpert MTB/RIF assay (Xpert) is a rapid test for tuberculosis (TB) and rifampin resistance (RIF-R) suitable for point-of-care ...Xpert MTB/RIF Ultra assay (Ultra) to improve per- ...on ...
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Comparison of the Xpert MTB/RIF Test with an IS6110 TaqMan Real Time PCR Assay for Direct Detection of Mycobacterium tuberculosis in Respiratory and Nonrespiratory Specimens
... of Mycobacterium tuberculosis complex (MTBC) in clinical ...Xpert MTB/RIF is an on-demand assay described as a simple method that can be performed by personnel with minimal training and can provide ...
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Prevalence of rifampicin resistant Mycobacterium tuberculosis among presumptive tuberculosis patients in selected governmental hospitals in Addis Ababa, Ethiopia
... TB. Mycobacterium tuberculosis culture, the gold standard test, is limited only to regional laboratories and primarily used for research ...Xpert MTB/RIF assay is now going to be implemented in all ...
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Evaluation of the Abbott RealTime MTB and RealTime MTB INH/RIF Assays for Direct Detection of Mycobacterium tuberculosis Complex and Resistance Markers in Respiratory and Extrapulmonary Specimens
... of tuberculosis (TB) and fast de- tection of drug resistance are essential to ensure early initia- tion of appropriate antituberculotic treatment, adequately man- age the disease, and control further ...of ...
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Clinical Evaluation of TRCRapid M TB for Detection of Mycobacterium tuberculosis Complex in Respiratory and Nonrespiratory Specimens
... of tuberculosis is crucial to providing optimal treatment and reducing the spread of ...automated Mycobacterium tuberculosis complex (MTBC) rRNA detection kit (TRCRapid ...
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Specific detection of Mycobacterium tuberculosis complex strains by polymerase chain reaction
... Mycobacterium tuberculosis Mycobacterium tuberculosis Mycobacterium tuberculosis Mycobacterium tuberculosis Mycobacterium africanum Mycobacterium bovis Mycobacterium bovis BCG Mycobacter[r] ...
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Comparison of Xpert MTB/RIF with Line Probe Assay for Detection of Rifampin Monoresistant Mycobacterium tuberculosis
... Xpert MTB/RIF assays have shown good performance (98% sen- sitivity) for RIF resistance detection compared with the gold stan- dard phenotypic DST ...Xpert MTB/RIF assay has further improved the TAT, and ...
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Detection of Mycobacterium tuberculosis in pediatric stool samples using TruTip technology
... and Mtb can be detected in stool using Xpert [5–10] or other laboratory-developed PCR assays ...both Mtb and expanded drug resistance testing-criteria listed in the target product profile for novel TB ...
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Structure based drug discovery for designing leads for the non toxic metabolic targets in multi drug resistant Mycobacterium tuberculosis
... of Mtb by effectively acting on ...the Mtb genome, obtained through a crowd sourcing approach was previously used by us to recon- struct the metabolic network of Mtb in a bottom up manner ...
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Design and synthesis of imidazolylmethyl substituted fluorobenzimidazoles for antitubercular and antifungal activity
... that Mycobacterium tuberculosis (Mtb) cytochrome p-450 could be a novel Mtb drug target ...pathogenic Mycobacterium tuberculosis (Mtb) H37Rv strain and antifungal activity ...
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A statistical method for comparing chest radiograph images in MTB patients
... Abstract :- Digital images of chest radiograph taken at different time points may be compared to investigate the effect of treatment on mycobacterium tuberculosis (MTB) patients. One method of ...
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Identification of Mycobacterium Species by secA1 Sequences
... We describe a novel molecular method for the differentiation and identification of 29 mycobacterial species. The target is the secA1 gene that codes for the essential protein SecA1, a key component of the major pathway ...
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Mutations in Codon 315 of the katG Gene Associated with High-level Resistance to Isoniazid
... in mycobacterium tuberculosis (MTB) isolates randomly collected from sputums of 42 patients with active pulmonary tuberculosis in different regions of ...
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