myosin heavy chain 3
Cardiac beta myosin heavy chain diversity in normal and chronically hypertensive baboons
... beta-myosin heavy chains (MHCs) present in baboon myocardium by electrophoresis in gradient pore gels and by Western blots with anti-MHC ...Ca2+-activated myosin ATPase activity in hypertrophied left ...
8
Myosin Heavy Chain Expression and Oxidative Modifications in Diabetic Rat Hearts
... It is well known that the prime determinant of the con- tractile properties, particularly the maximum shortening velocity, in the muscle cell is the catalytic activity of myofibrillar ATPase (my-ATPase) which resides in ...
9
The myosin light chain 1 isoform associated with masticatory myosin heavy chain in mammals and reptiles is embryonic/atrial MLC1
... masticatory myosin, with the addition of raccoon, lion, coyote, big brown bat, tiger quoll, feathertail glider, sugar glider, American alligator, common snapping turtle, spiny softshell turtle, painted turtle, ...
10
Masticatory (`superfast') myosin heavy chain and embryonic/atrial myosin light chain 1 in rodent jaw closing muscles
... = 3), southern flying squirrels (Glaucomys volans Linnaeus, N = 3), red squirrel (Tamiasciurus hudsonicus Erxleben, N = 3), eastern fox squirrel (Sciurus niger Linnaeus, N = 2), woodchuck (Marmota ...
9
Myosin heavy chain gene expression in human heart failure
... of myosin heavy chain (MyHC), a and b , ex- ist in the mammalian ventricular myocardium, and their relative expression is correlated with the contractile velocity of cardiac ...
10
Sequence requirements for myosin gene expression and regulation in Caenorhabditis elegans.
... Four Caenorhabditis elegans genes encode muscle-type specific myosin heavy chain isoforms: myo-1 and myo-2 are expressed in the pharyngeal muscles; unc-54 and myo-3 [r] ...
20
GAP45 Phosphorylation Controls Assembly of the Toxoplasma Myosin XIV Complex
... the myosin XIV motor complex of Toxo- plasma gondii consists of four proteins, namely, the myosin XIV heavy chain (MyoA), MLC1, the membrane anchor GAP50, and GAP45 ...FIG. 3. mycGAP45 ...
7
Calpain 3 is important for muscle regeneration: Evidence from patients with limb girdle muscular dystrophies
... For immunohistochemistry, all sections were, fixed in acetone and methanol (1:1) or 4% paraformaldehyde (for MyoD), and subsequently blocked in buffer (3% fetal calf serum in PBS) prior to staining. Primary ...
11
The Role of Evolutionarily Conserved Sequences in Alternative Splicing at the 3′ End of Drosophila melanogaster Myosin Heavy Chain RNA
... as myosin, actin, tropomyosin, and troponin are Skip splicing of exon 17 to exon 19 generates a MHC important to generating the functional differences carboxy terminus containing 27 amino acids encoded among ...
14
A study of the myosin heavy chain gene family in the carp
... non myosin cDNA's. By the nature of 3' RACE PCR the 3' oHgonucleotide must consist o f a long tail o f thymidine nucleotides, to facihtate annealing with the poly (A) tail o f the RNA molecule during ...
208
Myosin heavy chain and physiological adaptation of the rat diaphragm in elastase-induced emphysema
... Elastase-induced emphysema in rodents is the most wide- ly studied animal model for human emphysema. Several alterations in diaphragmatic structure and function have been demonstrated in this model. Among these are dia- ...
10
Characterization of genomic myosin heavy chain gene isoforms and their 5' regulatory elements in rabbit: applications for gene therapy.
... AGTAGGGGGG 3 0 1 TACAGGGAAT GGTATGCTGT GTGCAGTGGA CAACTTGGGG AGAAGCAAGA AGATGAACAG 3 6 1 CATGCAAATT CTGAAGCTAC AAGAATGCTG GAACAACCAA GAGAGGACTT TNTNCCTTTT 4 2 1 TAAAGTGTTG AAACACGTAG CTTGATTTNG CAGACTGGAA ...
265
The isolation and function of the 3'untranslated region of the myosin heavy chain genes of skeletal muscle
... MyHC 3’UTRs was investigated by electrophoretic mobility ...chapter 3 did not conclusively demonstrate a regulatory fimction for the MyHC 3’UTRs in gene expression and mRNA stability, this did not ...
265
Identification of a new mechanism for targeting myosin II heavy chain phosphorylation by Dictyostelium myosin heavy chain kinase B
... cytokinesis in suspension culture and multicellular development, should be compromised [3]. To this end, we compared the suspension culture growth rates of Dictyostelium cells over-expressing full-length MHCK-B, ...
9
Phylogenetic implications of the superfast myosin in extraocular muscles
... the 3′ region of an 800-nucleotide non-coding sequence that exhibits greater than 75 % sequence identity between human and ...extraocular myosin heavy chain gene from the other members of the ...
13
Androgen receptor is expressed in mouse cardiomyocytes at prenatal and early postnatal developmental stages
... The involvement of androgens in gender-related cardio- vascular diseases [1] explains the interest for the study of the role of sexual steroids on cardiac myocytes. There are sex-related differences in mRNA expression of ...
6
Regulation of contractile proteins by phosphorylation
... The two major contractile proteins, actin and myosin, polypeptide chain, myosin is a hexamer composed of are not only responsible for the contraction of skeletal, a pair of heavy chains [r] ...
5
The effects of temperature acclimation on the expression of contractile protein isoforms in the skeletal muscle of the common carp (Cyprinus carpio)
... isomyosins. The existance in both fast and slow muscle of two MHCs and three MLCs (Staron & Pette, 1987a; Billeter et al. 1981), means that nine fast and nine slow isomyosins could exist. However, possibly due to the ...
205
Interleukin 1 beta modulates the growth and phenotype of neonatal rat cardiac myocytes
... beta-myosin heavy chain (beta- MHC) mRNA (> 10-fold, n = 4), and decreased mRNA levels for sarcoplasmic reticulum Ca(2+)-ATPase (SERCA2) (-46 +/- 7%; P < ...
8
Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease
... by myosin regulatory proteins (for example, myosin light chain-2 [MLC2]) in cardiac muscle remain poorly ...Cardiac myosin cycling kinetics, which directly control actin-myosin ...
14