myosin heavy chain isoform
A study of the role of glycogen in skeletal muscle performance and of myosin heavy chain isoform expression in amphibian skeletal muscle using the toad Bufo marinus
... It is worthwhile to point out that whilst glycogen may be an important factor implicated in the 'run-down' phenomenon observed in mechanically skinned fibres under the conditions used [r] ...
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Coordinate Changes in Myosin Heavy Chain Isoform Gene Expression Are Selectively Associated With Alterations in Dilated Cardiomyopathy Phenotype
... In summary, the data presented in this study in- dicate that in chronic heart failure patients with a di- lated cardiomyopathy phenotype changes in MyHC isogene expression measured in septal endomyocar- dial biopsy ...
11
Glucocorticoid induced alterations in titin, nebulin, myosin heavy chain isoform content and viscoelastic properties of rat skeletal muscle
... treated with dexamethasone [4,5,14]. The decreased ratio between nebulin and MHC in atrophied muscle indicated that nebulin declined to a greater extent than titin. Taking into account the decreased hind-limb grip ...
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Quantifying Regional-Scale Water Storage Using Models and Observations: Application For Drought Assessment In South Carolina
... be myosin heavy chain isoform shifts that occur under certain ...a myosin heavy chain isoform shift is occurring seeing as how it has a intermediate contractile ...
65
Myosin heavy chain gene expression in human heart failure
... because they are the molecular motors of muscle. Two types of MyHC are expressed in the mammalian heart, a - and b -MyHC. The a -MyHC has a higher ATPase activity than b -MyHC, and the contractile velocity of the heart ...
10
The myosin light chain 1 isoform associated with masticatory myosin heavy chain in mammals and reptiles is embryonic/atrial MLC1
... jaw-closing isoform has unique electrophoretic mobility, compared with cardiac MHC isoforms, in these ...MHC isoform in lion masseter and temporalis had an electrophoretic mobility that was distinct from ...
10
Masticatory (`superfast') myosin heavy chain and embryonic/atrial myosin light chain 1 in rodent jaw closing muscles
... weight heavy chains, MHC, and two pairs of light chains, ...the isoform expression of MHC and of MLC among vertebrate species, in general, and among individual muscle cells within a given ...Masticatory ...
9
A study of the myosin heavy chain gene family in the carp
... MyoHC isoform conq)osition is responsible for the measured differences in myofibrillar ATPase, contractile properties and swimming performance observed between warm and cold acclimated ...
208
Functional significance of cardiac myosin essential light chain isoform switching in transgenic mice
... two heavy chains as well as two regula- tory and two essential light chains ...two heavy chain genes— a -MyHC and b -MyHC — have been extensively ...light chain 1a (ELC1a) is ubiqui- tously ...
11
Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy Interaction between hemodynamic and thyroid hormone induced signals
... In this study, the levels of expression of the two isoforms alpha and beta of myosin heavy chain MHC during cardiac hypertrophy were investigated at the messenger RNA mRNA and protein le[r] ...
9
Myosin Heavy Chain Expression and Oxidative Modifications in Diabetic Rat Hearts
... only myosin heavy chain (MHC) isoform transitions, but also reduced amounts in MHC protein; and 2) if diabetes results in declines in the MHC protein content, this change would relate to ...
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Increase in cardiac myosin heavy chain (MyHC) alpha protein isoform in hibernating ground squirrels, with echocardiographic visualization of ventricular wall hypertrophy and prolonged contraction
... cardiac myosin heavy-chain (MyHC) isoforms in a separate cohort of squirrels over 5 months, including time points before hibernation, during hibernation and just prior to ...alpha isoform is ...
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Myosin heavy chain and physiological adaptation of the rat diaphragm in elastase-induced emphysema
... slower isoform is not as marked as that reported in humans [12,13], in which MHC type I is upregulated and both IIa and IIx are down- regulated, there is precedent for restricted MHC adapta- tion in ...slow ...
10
Congenital myopathies: clinical phenotypes and new diagnostic tools
... termed myosin storage myopathy [35], is a rare condi- tion associated with mutations in a myosin heavy chain beta (MHC-β) isoform that is expressed primarily in the heart, but also in ...
16
Characterization of genomic myosin heavy chain gene isoforms and their 5' regulatory elements in rabbit: applications for gene therapy.
... expression of the construct pCC-D7/32 could have been caused by this fragment containing exons 1, 2 and the first nucleotides of exon 3 o f the MyHC gene. Also the likely presence of negative regulatory elements in the ...
265
A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart
... myocardium. Myosin regulatory light chain 2, ventricular/cardiac muscle isoform (MLC2v), which is involved in the development of human cardiomyopathy, is an important structural protein that affects ...
14
Androgen receptor is expressed in mouse cardiomyocytes at prenatal and early postnatal developmental stages
... mouse myosin, heavy polypeptide 6, cardiac muscle, alpha (NM_0011 64171)sense primer sequence: 5′-atctctgacaacgcctatc-3′ and antisense primer sequence: 5′-gataggcgttgtcagagat-3′; mouse myosin, ...
6
The effects of temperature acclimation on the expression of contractile protein isoforms in the skeletal muscle of the common carp (Cyprinus carpio)
... isomyosins. The existance in both fast and slow muscle of two MHCs and three MLCs (Staron & Pette, 1987a; Billeter et al. 1981), means that nine fast and nine slow isomyosins could exist. However, possibly due to the ...
205
Mouse and computational models link Mlc2v dephosphorylation to altered myosin kinetics in early cardiac disease
... by myosin regulatory proteins (for example, myosin light chain-2 [MLC2]) in cardiac muscle remain poorly ...Cardiac myosin cycling kinetics, which directly control actin-myosin ...
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Differentiation and long term survival of C2C12 myoblast grafts in heart
... Grafted C2C 12 myoblasts underwent myogenic differentiation as evidenced by both the induction of skeletal myosin heavy chain expression and the presence of highly differentiated ultrast[r] ...
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