Myosin II
Slit and Netrin-1 guide cranial motor axon pathfinding via Rho-kinase, myosin light chain kinase and myosin II
... and myosin light chain kinase (MLCK), which regulate myosin II activity, controlling actin retrograde flow in the growth ...and myosin II are required for Slit and Netrin-1-mediated ...
15
Myosin II regulates extension, growth and patterning in the mammalian cochlear duct
... As discussed above, previous results had suggested that a considerable amount of cochlear convergence and extension occurs between E14 and E16.5. To determine whether the effects of myosin II are limited to ...
10
Identification of a new mechanism for targeting myosin II heavy chain phosphorylation by Dictyostelium myosin heavy chain kinase B
... of myosin II assembly in cells over-expressing full-length MHCK-B, MHCK-B- Δ -WD, or MHCK- Δ ...pair. Myosin II heavy chain was detected in the fractions using polyclonal antibody specific the ...
9
Myosin II is not required for Drosophila tracheal branch elongation and cell intercalation
... by Myosin II (MyoII)-dependent forces during tissue elongation in the Drosophila embryo that lead to germ-band extension, it remained unclear whether MyoII plays a similar active role during tracheal branch ...
8
Angiotensin-II Mediates Nonmuscle Myosin II Activation and Expression and Contributes to Human Keloid Disease Progression
... Ang II and its nonhypertensive analog angiotensin (1–7) accelerates dermal repair in ro- dents ...Ang II signal- ing in keloid pathogenesis is unknown. Nonmuscle myosin II (NMM II) is ...
8
Characterization of the minimum domain required for targeting budding yeast myosin II to the site of cell division
... components, myosin II, are important for localising the molecule to the contractile ring (CR) during ...how myosin II is recruited to the site of cell division and how this recruitment relates ...
12
Actin depolymerisation and crosslinking join forces with myosin II to contract actin coats on fused secretory vesicles
... when myosin II motor activity is ...bipolar myosin filaments walk along antiparallel actin filaments might not be sufficient for efficient and complete contraction of the actin ...that myosin ...
12
Evidence of a Role for Nonmuscle Myosin II in Herpes Simplex Virus Type 1 Egress
... the myosin family play a role(s) in the transport of intracellular organelles and vesicles ...muscle myosin II appears to be the only member of the myosin super-family with the ability to form ...
11
How a Cell Crawls and the Role of Cortical Myosin II
... Translocation of the uropod. Although we initially consid- ered the uropod and main cell body a single motile entity, especially since there was no visible cytoplasmic barrier be- tween the two as was the case at the ...
16
A novel positive selection for identifying cold-sensitive myosin II mutants in Dictyostelium.
... myosin head mutations, we targeted the mutant gene by homologous recombination with a tail fragment and then recovered the integrated plasmid along with the adjacent [r] ...
11
Cochlear outer hair cells undergo an apical circumference remodeling constrained by the hair bundle shape
... of myosin II, myosin VIIa, Shroom2 and F-actin during the transition were not observed elsewhere than inside OHCs or at the apical junctions of OHCs with their supporting ...
11
Distinct cytoskeleton populations and extensive crosstalk control Ciona notochord tubulogenesis
... The GFP and mCherry-hActin (which expresses human actin) expression clones were described previously (Dong et al., 2009). Ciona ERM expression construct ERM-EGFP (Hotta et al., 2007) was a gift from Hiroki Takahashi. ...
11
RasC Plays a Role in Transduction of Temporal Gradient Information in the Cyclic-AMP Wave of Dictyostelium discoideum
... both myosin II and myosin I. In the case of myosin II, localization is effected by phosphorylation- dephosphorylation of both the heavy chain (7; ...
17
Induced Paternal Effects Mimic Cytoplasmic Incompatibility in Drosophila
... Identification of host genes with altered expression due to Wolbachia infection: The screening of a sub- traction cDNA library prepared from mRNA of infected and uninfected D. simulans Riverside males (DSR and DSRT, ...
8
A role for actomyosin contractility in Notch signaling
... non-muscle myosin II in this background. Non-muscle myosin II is a multimeric motor protein complex whose heavy chain is encoded by the Drosophila gene zipper, and regulatory light chain (RLC) ...
15
Identification and characterisation of a type II myosin in the fission yeast <italic>Schizosaccharomyces pombe</italic>
... as myosin II in higher eukaiyotes, it might be expected that Myo2p would be a component of the actin ring and that deletion would have a sim ilar effect as the deletion of other actin ring components which ...
216
Steric hindrance in the upper 50 kDa domain of the motor Myo2p leads to cytokinesis defects in fission yeast
... The fission yeast Schizosaccharomyces pombe is an attractive model organism to understand eukaryotic cytokinesis mechanisms because it divides using a contractile actomyosin ring (Goyal et al., 2011; Pollard, 2008; ...
8
MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development
... of myosin II’s ATPase func- tion restricted the ability of MYL6B to negatively regulate p53 protein level ...muscle myosin may exert opposite effects on p53 dependent on the tissue context and tumor ...
8
Actomyosin contractility and Discs large contribute to junctional conversion in guiding cell alignment within the Drosophila embryonic epithelium
... muscle Myosin II and the polarity proteins Discs large (Dlg) and Bazooka are enriched along cell interfaces in a complex but reproducible pattern that suggests their involvement in junctional conversion and ...
10
Metastasis of aggressive amoeboid sarcoma cells is dependent on Rho/ROCK/MLC signaling
... phosphorylated myosin light chain (MLC) to the lead- ing edge of the ...non-muscle myosin II ATPases activity inhibitor Blebbistatin and insensitive to the presence of a broad- spectrum ...
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