Myosin light chain 2
PKM2, function and expression and regulation
... MLC2: myosin light chain 2; MiR/miRNA: microRNA; MUC-1: Mucin-1; mTORC l: mammalian rapamycin target protein sensitive complex 1; NADH: nicotinamide adenine dinucleotide; NADPH: ...
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The influence of temperature on muscle development in the teleost 'Pleuronectes platessa L '
... of myosin and the maximum velocity of fibre shortening are generally recognised to be linked to the myosin heavy chain composition (Barany 1967, Reiser et ...the light chain 3 content ...
217
Respiratory syncytial virus-associated mortality in a healthy 3-year-old child: a case report
... polymerase chain reaction in an abundant, exudative pericardial ...in myosin light chain 2, which was also found in two other healthy members of the ...
8
The myosin light chain 1 isoform associated with masticatory myosin heavy chain in mammals and reptiles is embryonic/atrial MLC1
... masticatory myosin is the predominantly expressed myosin in jaw-closing muscles of several rodent species, all being members of the Sciuridae ...Masticatory myosin in Sciuridae consists of MHC-M, the ...
10
The Cytomegalovirus Enhancer Induces an Immediate Response to the Myosin Light Chain 2v Promoter during P19CL6 Cell Differentiation
... P19CL6 cells derived from P19 embryonic carcinoma cells can efficiently diffe- rentiate into cardiac muscle cells in the presence of 1% dimethyl sulfoxide (DMSO) [1]. Such a property is a good tool for the study of ...
14
Functional significance of cardiac myosin essential light chain isoform switching in transgenic mice
... ( 2 dP/dt) and contraction ( 1 dP/dt) are significantly increased in the Langendorff prepa- rations, and in a transgene dose-dependent ...as myosin from TG mice translocates actin at significantly higher ...
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Masticatory (`superfast') myosin heavy chain and embryonic/atrial myosin light chain 1 in rodent jaw closing muscles
... = 2), woodchuck (Marmota monax Linnaeus, N = 1) and Virginia opossum (Didelphis virginiana Kerr, N = ...masticatory myosin on ...electrophoresis. Myosin was extracted from single skinned fibers and ...
9
Functions of the Caenorhabditis elegans Regulatory Myosin Light Chain Genes mlc-1 and mlc-2
... redundant in the pharynx and that mlc-2(0) larvae arrest Actomyosins are known to be important for C. elegans development due only to an insufficient quantity of embryogenesis ( Strome and Wood 1983; Priess and ...
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Regulation of human heart contractility by essential myosin light chain isoforms
... the myosin-S1 fragment ...(phosphorylatable) myosin light chains, namely two ventricular-specific (VLC-2 and VLC- 2*) and an atrial-specific (ALC-2) (8, ...latory light ...
8
Role of calmodulin in platelet aggregation Structure activity relationship of calmodulin antagonists
... 20,000-dalton myosin light chain from platelets correlated well with the magnitude of their binding affinity to ...20,000-dalton myosin light chain ...
9
Attenuated platelet aggregation in patients with septic shock is independent from the activity state of myosin light chain phosphorylation or a reduction in Rho kinase-dependent inhibition of myosin light chain phosphatase
... A washed platelet-rich pellet from 2 ml of whole blood was solubilised in 200 μ l glycerol-free sample buffer containing 50 mM Tris-HCl, pH 6.8, 1% ( w / v ) SDS, 1× cOmplete™ protease inhibitor cocktail (Roche, ...
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Protein Kinase A Regulates beta-2 Integrin Avidity Activation and Subsequent Neutrophil Activation via Modulation of Myosin Light Chain Kinase.
... Ca 2+ and 1mM Mg 2+ (HBSS++) at a concentration of 2X10 6 cells/mL and treated with vehicle control or various PKA and MLCK inhibitors at the indicated concentration for 30 minutes at 37 0 ...
126
Differential proteome analysis of human embryonic kidney cell line (HEK-293) following mycophenolic acid treatment
... 12, myosin regu- latory light chain 2 (MLC2), peroxiredoxin1 (Prdx1) and profilin ...Figure 2 shows an exemplary gel of DMSO (vehicle) and MPA with marked regulated ...
12
A cardiac myosin light chain kinase regulates sarcomere assembly in the vertebrate heart
... Using 5′-RACE, we identified specific sequences identical to those of NM_182493 (MYLK3) located 4 kb upstream of the probe set sequence. The relative expression level of this candidate gene was significantly correlated ...
14
Functionally significant allelic variation in myosin light chain composition in a tropical cichlid
... upper myosin light chain 1; LC1 f2 *, lower myosin light chain 1; LC n , myosin light chain 1 from ...
8
Slit and Netrin-1 guide cranial motor axon pathfinding via Rho-kinase, myosin light chain kinase and myosin II
... As previous experiments had shown that cranial motor axons expressing dominant negative forms of Robo receptors for Slits show striking axon pathfinding defects [7], we expressed dominant negative forms of the Netrin ...
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Inverse relationship of Rho kinase and myosin-light chain kinase expression in the aging human detrusor smooth muscle
... Human detrusor samples were obtained from 41 pa- tients with an average age of 67 ± 10 years (mean ± S.D.; range 46–84 years old; 33 male and 8 female patients, Table 1). These specimens (1–2 cm width) were pre- ...
9
Imatinib relaxes the pulmonary venous bed of guinea pigs
... Ca 2+ -levels or/and Ca 2+ -sensitivity of the ...Ca 2+ -desensitizing manner: 1) cAMP blocks myosin light chain kinase (MLCK); 2) cAMP acti- vates myosin ...
13
Genetic Interaction Between Calcineurin and Type 2 Myosin and Their Involvement in the Regulation of Cytokinesis and Chloride Ion Homeostasis in Fission Yeast
... essential myosin light chain Compared with the wild type, ⌬ppb1 cells exhibited an mutant cdc4-8 required calcineurin activity for its growth approximately threefold increased frequency of medial and ...
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A small molecule inhibitor of T gondii motility induces the posttranslational modification of myosin light chain 1 and inhibits myosin motor activity
... Isolated myosin motor complexes were resolved by SDS-PAGE along with protein standards (Phosphor- ylase b 94kDa; Albumin 67kDa; Ovalbumin 43kDa; Carbonic anhydrase 30kDa; Trypsin inhibitor ...of myosin ...
12