Nanoparticle-protein corona: implication on cellular interactions
Protein corona: implications for nanoparticle interactions with pulmonary cells
... Our data on proteins in particle coronas showed that transferrin, albumin and A1AT varied significantly among the four NPs. We tested the influence of albu- min coating on the fate of instilled Au NPs since it was the ...
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Nanoparticle-allergen interactions mediate human allergic responses: protein corona characterization and cellular responses
... ‘ corona ’ . Hence, the ‘ corona ’ defines the biological identity of the ENMs and could affect the response of the immune system to ENM ...the interactions of gold nanoparticles with different ...
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<p>MWCNT interactions with protein: surface-induced changes in protein adsorption and the impact of protein corona on cellular uptake and cytotoxicity</p>
... surface, protein conformational changes result in unnatural protein configurations that trig- ger phagocytosis and potential inflammatory ...the cellular uptake study, where uptake was higher than ...
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Nanoparticle-protein corona formation and immunotoxicity of zinc oxide nanoparticles
... Research on the nanotoxicity of ZnO NPs highlights the reactive nature of these NPs. Cytotoxic responses of ZnO NPs may largely depend on the cell type under investigation, exposure conditions or routes, and method of ...
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Role of Ligand Conformation on Nanoparticle-Protein Interactions
... the corona formation is a process that spans timescales of seconds, the relevant NP sizes for biomedical applications range from a few to hundreds of nanometer, whereas the thickness of the protein ...
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Cellular nanoparticle delivery by G-protein coupled receptors
... for nanoparticle drug ...a nanoparticle compared to small native ...distinct cellular uptake pathways, their strong fluorescence enables sensitive and highly resolved detection by fluorescence ...
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Lipid Corona Formation from Nanoparticle Interactions with Bilayers and Membrane-Specific Biological Outcomes
... systems, corona formation mechanisms remain ...lipid corona formation, ...nano-bio interactions and to help understand why some nanomaterial/ligand combinations are detrimental to organisms, like ...
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The Design, Fabrication, and Characterization of Nanoparticle-Protein Interactions for Theranostic Applications
... characterize cellular interactions, identify ideal synthesis and modification procedures, and compare its effectiveness to current ...the nanoparticle where it ...
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<p>Protein–Nanoparticle Interaction: Corona Formation and Conformational Changes in Proteins on Nanoparticles</p>
... the protein – nanoparticle interaction, a phenomenon termed as “ protein ...single protein. The process underlying corona formation is complicated and involves complex kinetics and ...
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<p>A Protein Corona Adsorbed to a Bacterial Magnetosome Affects Its Cellular Uptake</p>
... the cellular membrane used in their ...natural protein – protein ...are protein-rich mem- brane organelles 53 so the interaction between magnetosomes and plasma occurs through natural ...
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Controlling evolution of protein corona: a prosperous approach to improve chitosan-based nanoparticle biodistribution and half-life
... suppresses protein corona ...of protein corona during incubation with serum 21 ...with nanoparticle function and circulation in vivo 30,31 ...electrostatic interactions between ...
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A hyperspectral and toxicological analysis of protein corona impact on silver nanoparticle properties, intracellular modifications, and macrophage activation
... nano–bio interactions occur still remain largely ...in cellular responses to biomaterials, a new picture of nanotoxicity based on protein–nanomaterial interactions is recently beginning to ...
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Implication of Bemisia tabaci Heat Shock Protein 70 in Begomovirus-Whitefly Interactions
... and cellular basis underlying these coevolved begomovirus-whitefly ...these interactions, we undertook a study using ...shock protein 70 (HSP70) specifically responded to the presence of the ...
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<p>Amphiphilic nanogels: influence of surface hydrophobicity on protein corona, biocompatibility and cellular uptake</p>
... The corona represents the actual bio-nano-interface, med- iates cellular interactions and depicts the biological identity of a ...prevent cellular uptake by the RES, described as “ stealth ...
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Glycosylation on Nanoparticle-Cell Interactions
... deglycosylated nanoparticle-protein complexes remain a subject of future ...a protein corona on the physicochemical properties of nanoparticles and their cellular ...deglycosylated ...
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<div>Effects of the protein corona on liposome–liposome and liposome–cell interactions</div>
... Cellular uptake of liposomes before and after Pc formation It is well recognized that the PC affects the fate of particles in the bloodstream. 44 Notably, the PC can affect particle clear- ance by immune cells, 8 ...
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Could nanoparticle corona characterization help for biological consequence prediction?
... ideal nanoparticle concocted by chemists, meaning the biomolecular corona could have great biological and physiological repercussions, sometimes masking the expected effects of purposely grafted ...the ...
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Understanding the effect of phytochemical coated silver nanoparticles on mammalian cells and the protein interactions with the surface corona of these nanoparticles.
... 118 period to a maximum of 72 hours, as further testing can compromise normal cellular functioning due to low seeding density of the cells [8]. This thesis dealt with the development of a long term in vitro ...
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Proteomic analysis of intracellular protein corona of nanoparticles elucidates nano-trafficking network and nano-bio interactions
... interparticle interactions and increased the dispersity of ...the protein concentration using Bradford assay and found that only ...subsequent cellular transport ...
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Protein corona: a new approach for nanomedicine design
... but protein-adsorbed NPs that represent the true identity and therapeutic responses of NPs when they enter into the ...of protein–NP complex and its interactions is important to predict and govern ...
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