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Natural killer (NK) cells

Natural killer cells responsiveness to physical exercise: A brief review

Natural killer cells responsiveness to physical exercise: A brief review

... Natural killer cells (NK) are a group of peripheral blood lymphocytes which display cytotoxic ac- tivity against a wide range of tumour ...NK cells in the host defence against tumours without ...

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Biology of interleukin-6 production by human natural killer cells

Biology of interleukin-6 production by human natural killer cells

... Human natural killer (NK) cells are large granular lymphocytes that function predominantly as cytotoxic effector cells of the innate immune ...NK cells also function as regulators of ...

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Transplantation and innate immunity: the lesson of natural killer cells

Transplantation and innate immunity: the lesson of natural killer cells

... T cells, which, otherwise, could attack recipient-specific, either major (in large part) or minor histocompatibility, anti- gens, this resulting in extremely severe, often fatal, GVHD ...T cells in ...

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Recognition of Vaccinia Virus-Infected Cells by Human Natural Killer Cells Depends on Natural Cytotoxicity Receptors

Recognition of Vaccinia Virus-Infected Cells by Human Natural Killer Cells Depends on Natural Cytotoxicity Receptors

... Natural killer cells are important components of the im- mune responses to many viruses, yet with the exception of NK recognition of cytomegalovirus-infected cells (17, 25), the mechanisms ...

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Therapeutic Depletion of Natural Killer Cells Controls Persistent Infection

Therapeutic Depletion of Natural Killer Cells Controls Persistent Infection

... NK cells continued to impair viral control at later times of medium-dose LCMV clone 13 infection suggested a possible role for NK cells in the maintenance of viral persistence during infection with a high ...

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Killing of Avian and Swine Influenza Virus by Natural Killer Cells

Killing of Avian and Swine Influenza Virus by Natural Killer Cells

... transmission. Natural killer (NK) cells are one of the innate immune components playing an important role in fighting against influenza ...infected cells, the H5-NKp46 interactions were unable ...

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Natural killer cells and natural killer T cells in Lyme arthritis

Natural killer cells and natural killer T cells in Lyme arthritis

... NK cells, patients with antibiotic-responsive arthritis had higher frequencies of iNKT cells in SF than PB, but these cells were often absent in SF in patients with antibiotic-refractory ...iNKT ...

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KLRD1-expressing natural killer cells predict influenza susceptibility

KLRD1-expressing natural killer cells predict influenza susceptibility

... of natural killer (NK) cells at baseline in discovery cohorts and the held-out validation ...progenitor cells (HSPCs) at ...cytotoxic cells, as KLRD1 expression at baseline correlated ...

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Phenotypic and functional characterization of cord blood natural killer cells

Phenotypic and functional characterization of cord blood natural killer cells

... NK cells such as NKp44 on CB should be carried ...target cells are needed. Finally, the potential of NK cells to mediated the GVL effect and prevent relapse depends on the number and the cytotoxic ...

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Original Article Compromised natural killer cells in pulmonary embolism

Original Article Compromised natural killer cells in pulmonary embolism

... NK cells interact with virus to promote the occurrence of VTE remain largely ...infected cells or down-regulation of cer- tain activating NK cell receptors to reduce in their cytolytic effectiveness with ...

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Human Uterine Natural Killer Cells but Not Blood Natural Killer Cells Inhibit Human Immunodeficiency Virus Type 1 Infection by Secretion of CXCL12

Human Uterine Natural Killer Cells but Not Blood Natural Killer Cells Inhibit Human Immunodeficiency Virus Type 1 Infection by Secretion of CXCL12

... NK cells are present in the human FRT, where they play a critical role during implantation as well as in conferring pro- tection against potential pathogens (14, 20, 22, ...uNK cells isolated from ...

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Preparation of highly activated natural killer cells for advanced lung cancer therapy

<p>Preparation of highly activated natural killer cells for advanced lung cancer therapy</p>

... NK cells are innate lymphocytes that are part of the fi rst line of defense against tumor ...NK cells can recognize and kill tumor cells without the requirement of prior antigen ...NK cells to ...

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Increased CD160 expression on circulating natural killer cells in atherogenesis

Increased CD160 expression on circulating natural killer cells in atherogenesis

... NK cells from AS patients could increase their cytotoxic activity, contributing to increased col- lateral damages and associated inflammation in ath- erosclerotic sites since CD160 engagement by HVEM and MHC-I ...

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Natural killer cells: role in local tumor growth and metastasis

Natural killer cells: role in local tumor growth and metastasis

... NK cells will not rearrange their genes encoding for receptor antigen recognition, but they have the ability to recognize target cells directly through inhibitory or activating receptors expressed on the ...

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Intracellular Disposition of Fludarabine Triphosphate in Human Natural Killer Cells

Intracellular Disposition of Fludarabine Triphosphate in Human Natural Killer Cells

... NK cells, we would expect even larger interindividual variability in F-ara-ATP accumulation in NK cells from HCT ...NK cells may lead to variable killing of those cells after fludarabine ...

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Natural killer cells in patients with severe chronic fatigue syndrome

Natural killer cells in patients with severe chronic fatigue syndrome

... The results from studies on NK cells in CFS patients suggest a potential mechanism of CFS can be identified through a thorough study of NK cell-related activities. From our observations, reductions in lytic ...

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Activation of natural killer cells by rituximab in granulomatosis with polyangiitis

Activation of natural killer cells by rituximab in granulomatosis with polyangiitis

... NK cells degranulated significantly stronger in the pres- ence of soluble rituximab as compared to infliximab ...B cells, there was no difference in de- granulation between treatment with soluble rituximab ...

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Contributions of natural killer cells to the immune response against Plasmodium

Contributions of natural killer cells to the immune response against Plasmodium

... NK cells also correlated with reduced parasitaemia and was found to be independent of age ...NK cells, leading to reduced parasi- taemia and disease ...NK cells in the Malian cohort was 40% of the NK ...

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Role of human natural killer cells in health and disease.

Role of human natural killer cells in health and disease.

... NK cells constitutively express IL-2RP (p75) and, in the presence of IL-2, develop into lymphokine-activated killer (LAK) cells capable of killing a broad array of fresh or cultured tumo[r] ...

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Herpesvirus Evasion of Natural Killer Cells

Herpesvirus Evasion of Natural Killer Cells

... than cells infected with clinical isolates ...infected cells from efficient NK cell-mediated lysis ...whereas cells infected with strains lacking UL141 upregulated CD155 compared to mock-infected ...

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